SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 3c5r BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		4 / 7 ASP A 500
TYR A 492
ASP A 495
HIS A 471
 None
 1.19A 1t03A-3c5rA:
undetectable		 1t03A-3c5rA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 3c5r BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		5 / 12 VAL A 477
LEU A 465
LEU A 498
ILE A 509
ALA A 518
 None
 1.01A 4p65B-3c5rA:
undetectable
4p65D-3c5rA:
undetectable
4p65I-3c5rA:
undetectable
4p65J-3c5rA:
undetectable		 4p65B-3c5rA:
14.29
4p65D-3c5rA:
14.29
4p65I-3c5rA:
17.11
4p65J-3c5rA:
14.29