SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 8 ASP A 138
ASP A 117
TYR A 121
THR B 134
 None
 1.29A 1ceaA-3c60A:
undetectable
1ceaB-3c60A:
undetectable		 1ceaA-3c60A:
17.02
1ceaB-3c60A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3c60 TCR YAE62 ALPHA
CHAIN
(Mus
musculus) 		4 / 4 ALA A  85
GLN A  44
TYR A  38
LEU A  74
 None
 1.26A 1e6wC-3c60A:
undetectable		 1e6wC-3c60A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 7 LEU A  32
THR A  31
PRO A  30
GLY B  96
 None
 1.02A 2ddwB-3c60A:
undetectable		 2ddwB-3c60A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 7 TYR B  48
GLY A  94
THR A  97
TYR B  46
 None
 1.00A 2g70A-3c60B:
undetectable		 2g70A-3c60B:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 7 TYR B  48
GLY B  96
TYR B  46
ASP B  97
 None
 0.93A 2g70B-3c60B:
undetectable		 2g70B-3c60B:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 7 TYR B  48
GLY A  94
THR A  97
TYR B  46
 None
 0.99A 2g70B-3c60B:
undetectable		 2g70B-3c60B:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 6 TYR B  48
GLY B  96
TYR B  46
ASP B  97
 None
 1.01A 2g72A-3c60B:
undetectable		 2g72A-3c60B:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 7 TYR B  48
GLY B  96
TYR B  46
ASP B  97
 None
 1.01A 2g72B-3c60B:
undetectable		 2g72B-3c60B:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus) 		5 / 12 ALA B 233
VAL B 192
HIS B 203
PHE B 204
SER A 126
 None
 1.35A 2gl0A-3c60B:
undetectable
2gl0C-3c60B:
undetectable		 2gl0A-3c60B:
20.54
2gl0C-3c60B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus) 		5 / 12 HIS B 203
PHE B 204
SER A 126
ALA B 233
VAL B 192
 None
 1.36A 2gl0D-3c60B:
undetectable
2gl0E-3c60B:
undetectable		 2gl0D-3c60B:
20.54
2gl0E-3c60B:
20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 7 TYR B  33
TYR A  35
PRO A  43
TYR A  88
 None
 1.28A 2ombC-3c60B:
19.2
2ombD-3c60B:
14.7		 2ombC-3c60B:
32.08
2ombD-3c60B:
32.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		3 / 3 GLN B  83
THR B 105
TRP B  32
 None
 1.17A 2rctA-3c60B:
undetectable		 2rctA-3c60B:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3c60 TCR YAE62 ALPHA
CHAIN
(Mus
musculus) 		3 / 3 VAL A 120
VAL A 145
SER A 191
 None
 0.73A 3n8xB-3c60A:
undetectable		 3n8xB-3c60A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		3 / 3 TYR B  46
GLY B  56
ASP B  57
 None
 0.57A 3ou6C-3c60B:
undetectable		 3ou6C-3c60B:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		3 / 3 ASP B 222
LYS B 225
LEU B 213
 None
 0.97A 4ptjA-3c60B:
undetectable		 4ptjA-3c60B:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3c60 TCR YAE62 ALPHA
CHAIN
TCR YAE62 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 5 GLN A 122
LEU A 123
SER B 127
ASP A 196
 None
 1.37A 4qtuD-3c60A:
undetectable		 4qtuD-3c60A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 7 ASP B  93
GLY B  92
HIS B  27
ASN B  25
 None
 1.05A 5nnwD-3c60B:
undetectable		 5nnwD-3c60B:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3c60 TCR YAE62 BETA CHAIN
(Mus
musculus) 		4 / 7 ASP B  93
GLY B  92
HIS B  27
ASN B  25
 None
 1.01A 5no9D-3c60B:
undetectable		 5no9D-3c60B:
16.10