SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		3 / 4 VAL A  56
TRP A  63
TRP A  55
 None
 1.45A 1gmkC-3c64A:
undetectable
1gmkD-3c64A:
undetectable		 1gmkC-3c64A:
13.56
1gmkD-3c64A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.39A 1v54A-3c64A:
3.6
1v54C-3c64A:
4.6		 1v54A-3c64A:
15.51
1v54C-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.37A 1v54N-3c64A:
2.8
1v54P-3c64A:
1.4		 1v54N-3c64A:
15.51
1v54P-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 1v55A-3c64A:
2.9
1v55C-3c64A:
4.7		 1v55A-3c64A:
15.51
1v55C-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 6 TRP A  25
LEU A  19
LEU A 148
VAL A  56
 PG4  A 301 (-3.6A)
None
None
None
 1.12A 2dqyC-3c64A:
undetectable		 2dqyC-3c64A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.39A 2dyrA-3c64A:
3.1
2dyrC-3c64A:
4.9		 2dyrA-3c64A:
15.51
2dyrC-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.38A 2dyrN-3c64A:
undetectable
2dyrP-3c64A:
1.3		 2dyrN-3c64A:
15.51
2dyrP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.34A 2eijA-3c64A:
3.4
2eijC-3c64A:
1.4		 2eijA-3c64A:
15.51
2eijC-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 2eijN-3c64A:
2.3
2eijP-3c64A:
1.4		 2eijN-3c64A:
15.51
2eijP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.34A 2eikA-3c64A:
undetectable
2eikC-3c64A:
4.7		 2eikA-3c64A:
15.51
2eikC-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.35A 2eikN-3c64A:
2.3
2eikP-3c64A:
4.7		 2eikN-3c64A:
15.51
2eikP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.35A 2eilA-3c64A:
2.7
2eilC-3c64A:
3.8		 2eilA-3c64A:
15.51
2eilC-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.38A 2eilN-3c64A:
2.0
2eilP-3c64A:
4.8		 2eilN-3c64A:
15.51
2eilP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.41A 2y69A-3c64A:
2.8
2y69C-3c64A:
4.8		 2y69A-3c64A:
15.51
2y69C-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.38A 3abkA-3c64A:
3.7
3abkC-3c64A:
3.5		 3abkA-3c64A:
15.51
3abkC-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 3abkN-3c64A:
2.9
3abkP-3c64A:
4.3		 3abkN-3c64A:
15.51
3abkP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 3abmN-3c64A:
3.7
3abmP-3c64A:
1.3		 3abmN-3c64A:
15.51
3abmP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 3ag2A-3c64A:
undetectable
3ag2C-3c64A:
4.8		 3ag2A-3c64A:
15.51
3ag2C-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 3ag2N-3c64A:
2.1
3ag2P-3c64A:
4.9		 3ag2N-3c64A:
15.51
3ag2P-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.39A 3ag3A-3c64A:
2.7
3ag3C-3c64A:
4.7		 3ag3A-3c64A:
15.51
3ag3C-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.37A 3ag3N-3c64A:
3.4
3ag3P-3c64A:
4.8		 3ag3N-3c64A:
15.51
3ag3P-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 3ag4A-3c64A:
2.4
3ag4C-3c64A:
1.3		 3ag4A-3c64A:
15.51
3ag4C-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.35A 3ag4N-3c64A:
2.9
3ag4P-3c64A:
4.7		 3ag4N-3c64A:
15.51
3ag4P-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.38A 5b1aN-3c64A:
3.4
5b1aP-3c64A:
4.8		 5b1aN-3c64A:
15.51
5b1aP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.37A 5b1bN-3c64A:
3.0
5b1bP-3c64A:
4.7		 5b1bN-3c64A:
15.51
5b1bP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.36A 5b3sN-3c64A:
2.3
5b3sP-3c64A:
1.3		 5b3sN-3c64A:
15.51
5b3sP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.38A 5iy5A-3c64A:
2.5
5iy5C-3c64A:
1.4		 5iy5A-3c64A:
15.51
5iy5C-3c64A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.39A 5x1fN-3c64A:
undetectable
5x1fP-3c64A:
1.4		 5x1fN-3c64A:
15.51
5x1fP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.39A 5zcqN-3c64A:
3.1
5zcqP-3c64A:
4.8		 5zcqN-3c64A:
15.51
5zcqP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.34A 6nmfN-3c64A:
2.4
6nmfP-3c64A:
1.3		 6nmfN-3c64A:
15.51
6nmfP-3c64A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c64 PFEMP1 VARIANT 2 OF
STRAIN MC
(Plasmodium
falciparum) 		4 / 7 TRP A  63
THR A 134
TYR A 133
TRP A  14
 None
None
CL  A 501 (-4.8A)
None
 1.33A 6nmpN-3c64A:
3.1
6nmpP-3c64A:
1.3		 6nmpN-3c64A:
15.51
6nmpP-3c64A:
18.49