SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O96_E_SAME501_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	3c65	UVRABC SYSTEM PROTEIN C (Geobacillus kaustophilus)	5 / 9	LEU A 369 HIS A -2 GLY A 404 LEU A 449 ARG A 380	None	1.50A	5o96E-3c65A: undetectable 5o96F-3c65A: undetectable	5o96E-3c65A: 19.47 5o96F-3c65A: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3c65	UVRABC SYSTEM PROTEIN C (Geobacillus kaustophilus)	4 / 5	ILE A 450 PHE A 384 ARG A 433 THR A 437	None	1.12A	5z84N-3c65A: undetectable 5z84W-3c65A: undetectable	5z84N-3c65A: 16.02 5z84W-3c65A: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3c65	UVRABC SYSTEM PROTEIN C (Geobacillus kaustophilus)	4 / 8	ILE A 450 PHE A 384 ARG A 433 THR A 437	None	0.95A	5zcoA-3c65A: undetectable 5zcoJ-3c65A: undetectable	5zcoA-3c65A: 16.02 5zcoJ-3c65A: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_D_SUED1202_1 (NS3 PROTEASE)	3c65	UVRABC SYSTEM PROTEIN C (Geobacillus kaustophilus)	4 / 9	VAL A 399 LEU A 511 SER A 488 ASP A 453	None	0.95A	6c2mD-3c65A: undetectable	6c2mD-3c65A: 14.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5O96_E_SAME501_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","3c65","UVRABC SYSTEM PROTEIN C","Geobacillus kaustophilus",5,"LEU A 369;HIS A  -2;GLY A 404;LEU A 449;ARG A 380","None","1.50A","5o96E-3c65A:undetectable;5o96F-3c65A:undetectable","5o96E-3c65A:19.47;5o96F-3c65A:19.47"],["5Z84_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3c65","UVRABC SYSTEM PROTEIN C","Geobacillus kaustophilus",4,"ILE A 450;PHE A 384;ARG A 433;THR A 437","None","1.12A","5z84N-3c65A:undetectable;5z84W-3c65A:undetectable","5z84N-3c65A:16.02;5z84W-3c65A:14.71"],["5ZCO_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3c65","UVRABC SYSTEM PROTEIN C","Geobacillus kaustophilus",4,"ILE A 450;PHE A 384;ARG A 433;THR A 437","None","0.95A","5zcoA-3c65A:undetectable;5zcoJ-3c65A:undetectable","5zcoA-3c65A:16.02;5zcoJ-3c65A:14.71"],["6C2M_D_SUED1202_1","NS3 PROTEASE","3c65","UVRABC SYSTEM PROTEIN C","Geobacillus kaustophilus",4,"VAL A 399;LEU A 511;SER A 488;ASP A 453","None","0.95A","6c2mD-3c65A:undetectable","6c2mD-3c65A:14.81"]]