SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 GLU A 519
HIS A 537
ASP A 398
 None
None
MG  A   1 (-3.1A)
 0.84A 1i9gA-3c6aA:
undetectable		 1i9gA-3c6aA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		4 / 5 ALA A 560
PHE A 556
ILE A 413
ASP A 414
 None
 1.11A 1yc2D-3c6aA:
undetectable		 1yc2D-3c6aA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		4 / 7 VAL A 541
PHE A 523
THR A 522
LYS A 359
 None
 1.14A 2kotA-3c6aA:
undetectable		 2kotA-3c6aA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		4 / 6 GLY A 485
ILE A 454
ILE A 546
ASP A 483
 None
 0.95A 3a7eA-3c6aA:
undetectable		 3a7eA-3c6aA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		5 / 11 GLY A 548
ALA A 499
ILE A 362
LEU A 520
ILE A 504
 None
 1.07A 4dt8A-3c6aA:
undetectable		 4dt8A-3c6aA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		5 / 12 LEU A 410
CYH A 399
LEU A 467
TYR A 473
GLY A 460
 None
 1.44A 4zbrA-3c6aA:
undetectable		 4zbrA-3c6aA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 THR A 430
SER A 428
TYR A 407
 None
 0.87A 5jsdA-3c6aA:
undetectable		 5jsdA-3c6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 THR A 430
SER A 428
TYR A 407
 None
 0.87A 5jsdB-3c6aA:
undetectable		 5jsdB-3c6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 THR A 430
SER A 428
TYR A 407
 None
 0.87A 5jsdC-3c6aA:
undetectable		 5jsdC-3c6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 THR A 430
SER A 428
TYR A 407
 None
 0.88A 5jseA-3c6aA:
undetectable		 5jseA-3c6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 THR A 430
SER A 428
TYR A 407
 None
 0.86A 5jseB-3c6aA:
undetectable		 5jseB-3c6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3c6a TERMINASE LARGE
SUBUNIT
(Escherichia
virus
RB49) 		3 / 3 THR A 430
SER A 428
TYR A 407
 None
 0.86A 5jseC-3c6aA:
undetectable		 5jseC-3c6aA:
18.14