SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
3c6f YETF PROTEIN
(Bacillus
subtilis)
4 / 6 LEU A 173
ILE A 174
LEU A 194
GLU A 191
None
0.74A 4w5nA-3c6fA:
undetectable
4w5nA-3c6fA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
3c6f YETF PROTEIN
(Bacillus
subtilis)
5 / 9 ILE A 175
THR A 222
ASN A 183
LEU A 173
LEU A 220
None
1.29A 5fhzB-3c6fA:
undetectable
5fhzB-3c6fA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
3c6f YETF PROTEIN
(Bacillus
subtilis)
5 / 10 ILE A 175
THR A 222
ASN A 183
LEU A 173
LEU A 220
None
1.27A 5fhzC-3c6fA:
undetectable
5fhzC-3c6fA:
14.46