SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3c6l TCR 2W20 ALPHA CHAIN
(Mus
musculus) 		4 / 7 PHE A  61
ALA A  85
LEU A 107
VAL A 109
 None
 0.95A 1hk2A-3c6lA:
undetectable		 1hk2A-3c6lA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7Q_A_BEZA600_0
(COCAINE ESTERASE)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		5 / 10 ALA B  90
TYR B 100
PRO A  43
LEU B  41
PHE A 101
 None
 1.08A 1l7qA-3c6lB:
0.0		 1l7qA-3c6lB:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus) 		4 / 7 ILE A 174
ARG B 185
PHE A 139
ASP A 138
 None
 1.08A 2qebA-3c6lA:
undetectable		 2qebA-3c6lA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus) 		4 / 7 ILE A 174
ARG B 185
PHE A 139
ASP A 138
 None
 1.11A 2qebB-3c6lA:
undetectable		 2qebB-3c6lA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3c6l TCR 2W20 BETA CHAIN
(Mus
musculus) 		3 / 3 TYR B  46
GLY B  56
ASP B  57
 None
 0.53A 3ou6C-3c6lB:
undetectable		 3ou6C-3c6lB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		3 / 3 PHE B 101
GLN B  23
PHE A 101
 None
 0.71A 3rv5A-3c6lB:
undetectable		 3rv5A-3c6lB:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus) 		3 / 3 GLN B  99
PHE B 101
TYR A  35
 None
 0.89A 3ucjB-3c6lB:
undetectable		 3ucjB-3c6lB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus) 		3 / 3 GLN B  99
PHE B 101
TYR A  35
 None
 0.89A 3ucjA-3c6lB:
undetectable		 3ucjA-3c6lB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3c6l TCR 2W20 BETA CHAIN
(Mus
musculus) 		4 / 8 TYR B  62
THR B  18
TYR B  87
TRP B  32
 None
 1.19A 3wipB-3c6lB:
undetectable
3wipC-3c6lB:
undetectable		 3wipB-3c6lB:
22.39
3wipC-3c6lB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3c6l TCR 2W20 BETA CHAIN
(Mus
musculus) 		4 / 8 TYR B  62
THR B  18
TYR B  87
TRP B  32
 None
 1.20A 3wipC-3c6lB:
undetectable
3wipD-3c6lB:
undetectable		 3wipC-3c6lB:
22.39
3wipD-3c6lB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3c6l TCR 2W20 BETA CHAIN
(Mus
musculus) 		4 / 8 TRP B  32
TYR B  62
THR B  18
TYR B  87
 None
 1.25A 3wipA-3c6lB:
undetectable
3wipE-3c6lB:
undetectable		 3wipA-3c6lB:
22.39
3wipE-3c6lB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3c6l TCR 2W20 ALPHA CHAIN
(Mus
musculus) 		5 / 12 LEU A  45
ILE A  99
ALA A  90
LEU A  74
LEU A  20
 None
 0.95A 4o1zA-3c6lA:
undetectable		 4o1zA-3c6lA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		5 / 12 ALA A  44
GLU A  41
GLY A  40
GLN B   4
GLY B 104
 None
 1.03A 4uilH-3c6lA:
14.9
4uilL-3c6lA:
14.0		 4uilH-3c6lA:
27.19
4uilL-3c6lA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN
(Mus
musculus;
Mus
musculus) 		3 / 3 LYS A 124
ASP A 125
ARG B 234
 None
 0.80A 5jwaA-3c6lA:
undetectable
5jwaH-3c6lA:
undetectable		 5jwaA-3c6lA:
15.65
5jwaH-3c6lA:
15.65