SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		5 / 12 THR B 111
GLY B 235
ASP B 216
ILE B 221
ALA B 198
 None
 1.37A 1oltA-3c6qB:
undetectable		 1oltA-3c6qB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 5 SER B  95
TYR B 275
SER B 245
ASP B  91
 None
 1.47A 1vidA-3c6qB:
5.5		 1vidA-3c6qB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 6 LEU B  50
VAL B  71
ILE B  75
ILE B  61
 None
 0.89A 2piwA-3c6qB:
undetectable		 2piwA-3c6qB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 7 ILE B 277
ILE B 101
SER B 245
THR B 247
 None
 0.78A 3deuA-3c6qB:
undetectable		 3deuA-3c6qB:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 7 GLY B 113
GLY B 109
GLU B 118
ALA B 148
 None
 0.83A 3fpjB-3c6qB:
undetectable		 3fpjB-3c6qB:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 5 GLY B 122
LYS B 123
GLU B 153
GLY B 121
 None
 1.10A 3onnA-3c6qB:
2.7		 3onnA-3c6qB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 4 ILE B  72
SER B  95
ASP B  67
ASP B  42
 None
 1.41A 4krhB-3c6qB:
5.5		 4krhB-3c6qB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 7 VAL B 126
PHE B 186
ASN B 105
PHE B 145
 None
 0.98A 5hieC-3c6qB:
undetectable		 5hieC-3c6qB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 6 SER B 138
GLY B 188
ASN B 193
ILE B 159
 None
 1.15A 5j4nA-3c6qB:
undetectable		 5j4nA-3c6qB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		5 / 12 GLY B 194
LEU B 199
VAL B 127
VAL B 170
ALA B 169
 None
 0.91A 5kpcA-3c6qB:
undetectable		 5kpcA-3c6qB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3c6q SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Thermotoga
maritima) 		4 / 6 PRO B  13
TYR B 192
PRO B 219
LEU B 222
 None
 1.04A 5tl8A-3c6qB:
undetectable		 5tl8A-3c6qB:
21.31