SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_J_CHDJ103_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	3c6v	PROBABLE TAUTOMERASE/DEHALOGE NASE AU4130 (Aspergillus fumigatus)	5 / 11	LEU A 21 LEU A 90 GLU A 102 ALA A 63 LEU A 64	None	1.07A	4wg0J-3c6vA: undetectable 4wg0K-3c6vA: undetectable 4wg0L-3c6vA: undetectable	4wg0J-3c6vA: 9.17 4wg0K-3c6vA: 9.17 4wg0L-3c6vA: 9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_K_CHDK103_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	3c6v	PROBABLE TAUTOMERASE/DEHALOGE NASE AU4130 (Aspergillus fumigatus)	5 / 11	GLU A 102 ALA A 63 LEU A 64 LEU A 90 LEU A 21	None	1.18A	4wg0I-3c6vA: undetectable 4wg0J-3c6vA: undetectable 4wg0K-3c6vA: undetectable	4wg0I-3c6vA: 9.17 4wg0J-3c6vA: 9.17 4wg0K-3c6vA: 9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE5_A_OBNA1104_2 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	3c6v	PROBABLE TAUTOMERASE/DEHALOGE NASE AU4130 (Aspergillus fumigatus)	4 / 6	ILE A 66 VAL A 39 PHE A -2 ARG A 79	None	1.18A	4xe5A-3c6vA: undetectable	4xe5A-3c6vA: 9.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4WG0_J_CHDJ103_0","NUCLEAR RECEPTOR COACTIVATOR 2","3c6v","PROBABLE TAUTOMERASE\/DEHALOGENASE AU4130","Aspergillus fumigatus",5,"LEU A  21;LEU A  90;GLU A 102;ALA A  63;LEU A  64","None","1.07A","4wg0J-3c6vA:undetectable;4wg0K-3c6vA:undetectable;4wg0L-3c6vA:undetectable","4wg0J-3c6vA:9.17;4wg0K-3c6vA:9.17;4wg0L-3c6vA:9.17"],["4WG0_K_CHDK103_0","NUCLEAR RECEPTOR COACTIVATOR 2","3c6v","PROBABLE TAUTOMERASE\/DEHALOGENASE AU4130","Aspergillus fumigatus",5,"GLU A 102;ALA A  63;LEU A  64;LEU A  90;LEU A  21","None","1.18A","4wg0I-3c6vA:undetectable;4wg0J-3c6vA:undetectable;4wg0K-3c6vA:undetectable","4wg0I-3c6vA:9.17;4wg0J-3c6vA:9.17;4wg0K-3c6vA:9.17"],["4XE5_A_OBNA1104_2","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","3c6v","PROBABLE TAUTOMERASE\/DEHALOGENASE AU4130","Aspergillus fumigatus",4,"ILE A  66;VAL A  39;PHE A  -2;ARG A  79","None","1.18A","4xe5A-3c6vA:undetectable","4xe5A-3c6vA:9.63"]]