SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3c75 AMICYANIN
(Paracoccus
versutus) 		3 / 3 VAL A  24
VAL A  22
TRP A  46
 None
 0.78A 1av2A-3c75A:
undetectable
1av2B-3c75A:
undetectable		 1av2A-3c75A:
8.89
1av2B-3c75A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 HIS H 260
LEU H 266
TRP H 281
PHE H 259
 None
 1.29A 1ibgH-3c75H:
undetectable		 1ibgH-3c75H:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.24A 1oe1A-3c75A:
3.1		 1oe1A-3c75A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		5 / 5 HIS A  54
CYH A  93
PRO A  95
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
None
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.72A 1oe2A-3c75A:
4.7		 1oe2A-3c75A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.26A 1oe3A-3c75A:
undetectable		 1oe3A-3c75A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
METHYLAMINE
DEHYDROGENASE LIGHT
CHAIN
(Paracoccus
versutus) 		5 / 10 TYR H 150
ALA H 170
LEU H 174
MET L 117
GLY L  79
 None
 1.37A 1uhoA-3c75H:
undetectable		 1uhoA-3c75H:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 3c75 AMICYANIN
(Paracoccus
versutus) 		3 / 3 VAL A  24
VAL A  22
TRP A  46
 None
 0.90A 1w5uA-3c75A:
undetectable
1w5uB-3c75A:
undetectable		 1w5uA-3c75A:
8.89
1w5uB-3c75A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 10 ASP H 373
GLY H 415
GLY H 391
ILE H 419
LEU H 395
 None
 1.13A 1x7pA-3c75H:
undetectable
1x7pB-3c75H:
undetectable		 1x7pA-3c75H:
22.59
1x7pB-3c75H:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.60A 2fqdA-3c75A:
undetectable		 2fqdA-3c75A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.58A 2fqeA-3c75A:
undetectable		 2fqeA-3c75A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.59A 2fqfA-3c75A:
undetectable		 2fqfA-3c75A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.60A 2fqgA-3c75A:
undetectable		 2fqgA-3c75A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 3c75 AMICYANIN
(Paracoccus
versutus) 		3 / 3 VAL A  22
TRP A  46
VAL A  24
 None
 0.90A 2izqC-3c75A:
undetectable
2izqD-3c75A:
undetectable		 2izqC-3c75A:
8.89
2izqD-3c75A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 11 PHE H 246
PHE H 272
GLN H 179
ILE H 224
VAL H 205
 None
 1.41A 2vcdA-3c75H:
undetectable		 2vcdA-3c75H:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 4 ARG H 312
GLY H 286
GLU H 305
SER H 349
 None
 1.37A 2xctS-3c75H:
undetectable
2xctU-3c75H:
undetectable		 2xctS-3c75H:
21.59
2xctU-3c75H:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.27A 2xxgA-3c75A:
5.1		 2xxgA-3c75A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		5 / 5 HIS A  54
CYH A  93
PRO A  95
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
None
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.77A 2xxgC-3c75A:
5.1		 2xxgC-3c75A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 7 ARG H 172
GLN H 195
PHE H 196
PHE H 119
 None
 0.80A 2zxwC-3c75H:
undetectable
2zxwJ-3c75H:
undetectable		 2zxwC-3c75H:
19.95
2zxwJ-3c75H:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 ARG H 172
GLN H 195
PHE H 196
PHE H 119
 None
 0.77A 2zxwP-3c75H:
undetectable
2zxwW-3c75H:
undetectable		 2zxwP-3c75H:
19.95
2zxwW-3c75H:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 11 THR H 359
ILE H 333
LEU H 355
ILE H 363
VAL H 377
 None
 1.09A 3a51A-3c75H:
undetectable		 3a51A-3c75H:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 12 THR H 359
ILE H 333
LEU H 355
ILE H 363
VAL H 377
 None
 1.15A 3a51D-3c75H:
undetectable		 3a51D-3c75H:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 5 ARG H 172
GLN H 195
PHE H 196
PHE H 119
 None
 0.78A 3ablC-3c75H:
undetectable
3ablJ-3c75H:
undetectable		 3ablC-3c75H:
19.95
3ablJ-3c75H:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 ARG H 172
GLN H 195
PHE H 196
PHE H 119
 None
 0.88A 3ablP-3c75H:
undetectable
3ablW-3c75H:
undetectable		 3ablP-3c75H:
19.95
3ablW-3c75H:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 ARG H 172
GLN H 195
PHE H 196
PHE H 119
 None
 0.75A 3ag1C-3c75H:
undetectable
3ag1J-3c75H:
undetectable		 3ag1C-3c75H:
19.95
3ag1J-3c75H:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 7 GLY H 297
ASP H 292
TYR H 233
ARG H 278
 None
 1.34A 3arrA-3c75H:
undetectable		 3arrA-3c75H:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 5 ILE A  26
PHE A  83
PHE A  58
TYR A  91
 None
 1.37A 3em0A-3c75A:
undetectable		 3em0A-3c75A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		3 / 3 GLY A 101
TRP A  46
VAL A  24
 None
 0.75A 3n66B-3c75A:
undetectable		 3n66B-3c75A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 PRO H 282
VAL H 353
THR H 285
THR H 283
 None
 1.15A 3tneA-3c75H:
undetectable		 3tneA-3c75H:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		3 / 3 PHE A  98
CYH A  93
HIS A  96
 None
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
 1.20A 3u9fS-3c75A:
undetectable		 3u9fS-3c75A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3c75 METHYLAMINE
DEHYDROGENASE LIGHT
CHAIN
(Paracoccus
versutus) 		4 / 6 THR L  44
ASN L  45
GLY L  41
ASP L  37
 None
 1.23A 3w9tE-3c75L:
undetectable		 3w9tE-3c75L:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 ALA H 135
GLY H 203
LEU H 191
VAL H 205
 None
 0.83A 4dubB-3c75H:
undetectable		 4dubB-3c75H:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3c75 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.1A)
CU  A 107 (-3.3A)
CU  A 107 (-2.7A)
 0.58A 4ef3A-3c75A:
undetectable		 4ef3A-3c75A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		3 / 3 TYR H 326
ARG H 328
SER H 273
 None
 1.11A 4khpI-3c75H:
undetectable
4khpJ-3c75H:
undetectable		 4khpI-3c75H:
14.18
4khpJ-3c75H:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_2
(SERUM ALBUMIN)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 4 ARG H 317
GLU H 311
ASP H 341
ARG H 340
 None
 1.35A 4l9qB-3c75H:
undetectable		 4l9qB-3c75H:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3c75 AMICYANIN
METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
METHYLAMINE
DEHYDROGENASE LIGHT
CHAIN
(Paracoccus
versutus) 		4 / 8 HIS A  96
TYR H 222
ILE L 106
GLU L 101
 CU  A 107 (-3.3A)
None
None
None
 1.21A 4ms4A-3c75A:
undetectable		 4ms4A-3c75A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 5 ARG H 340
ARG H 312
GLY H 286
GLU H 305
SER H 349
 None
 1.42A 4z3oA-3c75H:
undetectable
4z3oB-3c75H:
undetectable		 4z3oA-3c75H:
19.95
4z3oB-3c75H:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 ARG H 172
GLN H 195
PHE H 196
PHE H 119
 None
 0.85A 5b1bC-3c75H:
undetectable
5b1bJ-3c75H:
undetectable		 5b1bC-3c75H:
19.95
5b1bJ-3c75H:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3c75 METHYLAMINE
DEHYDROGENASE LIGHT
CHAIN
(Paracoccus
versutus) 		4 / 8 ILE L 107
GLY L  33
THR L 122
LEU L  89
 None
None
TRQ  L  57 ( 3.4A)
None
 0.92A 5hwaA-3c75L:
undetectable		 5hwaA-3c75L:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 10 LEU H 207
GLY H 209
LEU H 191
VAL H 204
THR H 211
 None
 0.97A 5o96G-3c75H:
undetectable
5o96H-3c75H:
undetectable		 5o96G-3c75H:
19.95
5o96H-3c75H:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
METHYLAMINE
DEHYDROGENASE LIGHT
CHAIN
(Paracoccus
versutus;
Paracoccus
versutus) 		4 / 5 PHE L 102
THR L  91
ASP L 105
ASN H 235
 None
 1.01A 5ybbA-3c75L:
undetectable		 5ybbA-3c75L:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3c75 AMICYANIN
(Paracoccus
versutus) 		3 / 3 TYR A  31
HIS A  54
MET A  73
 None
CU  A 107 (-3.1A)
None
 1.10A 6af6A-3c75A:
undetectable		 6af6A-3c75A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 10 PHE H 102
THR H 115
ASP H 116
GLY H 113
ILE H 111
 None
 1.23A 6ebpB-3c75H:
undetectable		 6ebpB-3c75H:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		5 / 10 PHE H 102
THR H 115
ASP H 116
GLY H 113
ILE H 111
 None
 1.20A 6ebpC-3c75H:
undetectable		 6ebpC-3c75H:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 8 ASP H 105
ARG H  85
ASP H 380
GLU H 382
 None
 1.17A 6mn4A-3c75H:
undetectable		 6mn4A-3c75H:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		4 / 6 ASP H 105
ARG H  85
ASP H 380
GLU H 382
 None
 1.44A 6mn5D-3c75H:
undetectable		 6mn5D-3c75H:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN
(Paracoccus
versutus) 		3 / 3 ARG H 172
PHE H 196
PHE H 119
 None
 0.82A 6nknC-3c75H:
undetectable
6nknJ-3c75H:
undetectable		 6nknC-3c75H:
19.95
6nknJ-3c75H:
7.31