SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 ALA A 124
LEU A 151
LEU A 196
ALA A 199
 None
 0.50A 1e7cA-3c7jA:
2.2		 1e7cA-3c7jA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 ASP A 120
LEU A 115
LEU A 116
 None
 0.69A 1np1B-3c7jA:
undetectable		 1np1B-3c7jA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A 179
ILE A 140
HIS A 192
HIS A 148
HIS A 214
 None
None
NI  A 301 (-3.5A)
NI  A 301 (-3.4A)
NI  A 301 (-3.4A)
 1.33A 1tmxB-3c7jA:
undetectable		 1tmxB-3c7jA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 211
LEU A 151
LEU A 149
LEU A 195
 None
 1.03A 1yajD-3c7jA:
undetectable		 1yajD-3c7jA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 PHE A  56
LEU A  14
LEU A  47
LEU A  67
 None
 1.04A 2bfpA-3c7jA:
undetectable		 2bfpA-3c7jA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 PHE A  56
LEU A  14
LEU A  47
LEU A  67
 None
 0.86A 2bfpC-3c7jA:
undetectable		 2bfpC-3c7jA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 PHE A  56
LEU A  14
LEU A  47
LEU A  67
 None
 0.83A 2bfpD-3c7jA:
undetectable		 2bfpD-3c7jA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A 196
LEU A 151
SER A 112
ASP A 120
ALA A 118
 None
 1.11A 2br4F-3c7jA:
undetectable		 2br4F-3c7jA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ALA A 122
ALA A 124
LEU A 151
LEU A 196
ALA A 199
 None
 1.09A 2bxeA-3c7jA:
undetectable		 2bxeA-3c7jA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 LEU A 175
HIS A 148
HIS A 214
HIS A 192
 None
NI  A 301 (-3.4A)
NI  A 301 (-3.4A)
NI  A 301 (-3.5A)
 0.75A 2ow9A-3c7jA:
undetectable		 2ow9A-3c7jA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 175
HIS A 148
HIS A 214
HIS A 192
 None
NI  A 301 (-3.4A)
NI  A 301 (-3.4A)
NI  A 301 (-3.5A)
 0.74A 3kecA-3c7jA:
undetectable		 3kecA-3c7jA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ARG A  33
LEU A  70
LEU A  75
ILE A  36
 None
 0.93A 3s56B-3c7jA:
undetectable		 3s56B-3c7jA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 LEU A 175
HIS A 148
HIS A 214
HIS A 192
 None
NI  A 301 (-3.4A)
NI  A 301 (-3.4A)
NI  A 301 (-3.5A)
 0.76A 4a7bA-3c7jA:
undetectable		 4a7bA-3c7jA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 LEU A 195
ASN A 144
LEU A 131
GLU A 132
 None
NI  A 301 (-2.7A)
None
None
 1.21A 4nc3A-3c7jA:
undetectable		 4nc3A-3c7jA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 HIS A 214
LEU A 215
CYH A 207
LEU A 109
 NI  A 301 (-3.4A)
None
None
None
 1.42A 5hrqD-3c7jA:
undetectable
5hrqG-3c7jA:
undetectable
5hrqH-3c7jA:
undetectable		 5hrqD-3c7jA:
10.31
5hrqG-3c7jA:
10.45
5hrqH-3c7jA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A 195
LEU A 109
ALA A 108
GLY A 167
LEU A 168
 None
 1.10A 6b0iB-3c7jA:
undetectable		 6b0iB-3c7jA:
15.32