SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 5 ARG A 408
ALA A 407
LYS A 411
GLU A 452
 None
 1.19A 1e7cA-3c7oA:
undetectable		 1e7cA-3c7oA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 THR A   5
ILE A  17
ALA A 344
ASN A 342
THR A 308
 None
None
FMT  A2065 (-3.3A)
FMT  A2065 (-4.0A)
None
 1.10A 1jtxA-3c7oA:
undetectable		 1jtxA-3c7oA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 LEU A 204
VAL A 211
ILE A 202
TYR A 119
LEU A 161
 None
FMT  A2057 ( 4.5A)
None
None
None
 1.01A 1s19A-3c7oA:
undetectable		 1s19A-3c7oA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 4 THR A 149
GLY A 144
ASP A 141
ALA A  97
 GOL  A1734 ( 4.3A)
None
None
None
 1.05A 1sg9A-3c7oA:
undetectable		 1sg9A-3c7oA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 PHE A 283
ILE A  17
SER A 310
ASN A  14
ALA A 306
 None
 1.03A 1sg9C-3c7oA:
undetectable		 1sg9C-3c7oA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 GLY A 179
ALA A 178
ILE A 202
PRO A 146
ILE A 127
 None
 0.85A 2bpxB-3c7oA:
undetectable		 2bpxB-3c7oA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 10 ALA A 458
THR A 459
ALA A 407
VAL A 434
LYS A 432
 None
 0.96A 2f16K-3c7oA:
undetectable
2f16L-3c7oA:
undetectable		 2f16K-3c7oA:
18.09
2f16L-3c7oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 10 ALA A 458
THR A 459
ALA A 407
VAL A 434
LYS A 432
 None
 0.96A 2f16Y-3c7oA:
undetectable
2f16Z-3c7oA:
undetectable		 2f16Y-3c7oA:
18.09
2f16Z-3c7oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 7 PHE A 466
LEU A 437
ARG A 449
GLU A 359
 None
None
None
CA  A 488 (-3.4A)
 1.06A 2jn3A-3c7oA:
undetectable		 2jn3A-3c7oA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 9 LEU A 276
GLU A 338
ILE A 257
GLY A 258
GLY A 273
 None
 1.18A 2qmmA-3c7oA:
undetectable		 2qmmA-3c7oA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 5 LYS A 318
ASP A  53
TYR A 320
GLU A  44
 FMT  A2060 ( 4.0A)
FMT  A2060 (-3.6A)
None
None
 1.28A 2x8oA-3c7oA:
undetectable		 2x8oA-3c7oA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 HIS A 248
GLU A 256
HIS A 274
 None
 0.86A 3ba0A-3c7oA:
5.9		 3ba0A-3c7oA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 8 HIS A  20
HIS A  19
PHE A 363
GLY A  77
 None
 0.81A 3c0zB-3c7oA:
undetectable		 3c0zB-3c7oA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 4 PHE A 296
TYR A  35
VAL A 339
LEU A 328
 FMT  A2062 (-4.3A)
None
None
None
 1.46A 3keeD-3c7oA:
undetectable		 3keeD-3c7oA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 11 ALA A 458
THR A 459
ALA A 407
VAL A 434
LYS A 432
 None
 0.97A 3mg0K-3c7oA:
undetectable
3mg0L-3c7oA:
undetectable		 3mg0K-3c7oA:
18.09
3mg0L-3c7oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 HIS A 305
SER A 310
ASN A  54
 None
 0.77A 3s8pB-3c7oA:
undetectable		 3s8pB-3c7oA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 ARG A  33
GLU A 359
THR A 362
 None
CA  A 488 (-3.4A)
None
 0.79A 3v4tA-3c7oA:
undetectable		 3v4tA-3c7oA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 THR A 387
ASN A 478
GLU A 372
 None
FMT  A2055 ( 4.4A)
None
 0.66A 3v4tA-3c7oA:
undetectable
3v4tC-3c7oA:
undetectable		 3v4tA-3c7oA:
21.79
3v4tC-3c7oA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 ASP A 480
GLY A 378
TYR A 481
 CA  A 488 (-3.4A)
None
None
 0.67A 3w9tC-3c7oA:
undetectable		 3w9tC-3c7oA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 ASP A 480
GLY A 378
TYR A 481
 CA  A 488 (-3.4A)
None
None
 0.66A 3w9tG-3c7oA:
undetectable		 3w9tG-3c7oA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 HIS A  20
HIS A  19
PHE A 363
PRO A 380
GLY A  77
 None
 1.14A 4bz6A-3c7oA:
undetectable
4bz6B-3c7oA:
undetectable		 4bz6A-3c7oA:
20.92
4bz6B-3c7oA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 HIS A  20
HIS A  19
PHE A 363
PRO A 380
GLY A  77
 None
 1.17A 4bz6C-3c7oA:
undetectable		 4bz6C-3c7oA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 PHE A 465
VAL A 386
ILE A 389
 None
 0.55A 4emaA-3c7oA:
undetectable		 4emaA-3c7oA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 GLY A 179
ALA A 178
ILE A 202
PRO A 146
ILE A 127
 None
 0.88A 4njvD-3c7oA:
undetectable		 4njvD-3c7oA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 10 ALA A 458
THR A 459
ALA A 407
VAL A 434
LYS A 432
 None
 0.94A 4qvyK-3c7oA:
undetectable
4qvyL-3c7oA:
undetectable		 4qvyK-3c7oA:
19.42
4qvyL-3c7oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 10 ALA A 458
THR A 459
ALA A 407
VAL A 434
LYS A 432
 None
 0.94A 4qvyY-3c7oA:
undetectable
4qvyZ-3c7oA:
undetectable		 4qvyY-3c7oA:
19.42
4qvyZ-3c7oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 7 TYR A 259
TYR A 237
LEU A 229
PHE A 167
 None
 1.02A 4yv5A-3c7oA:
undetectable		 4yv5A-3c7oA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 7 TYR A 259
TYR A 237
LEU A 229
PHE A 167
 None
 1.06A 4yv5B-3c7oA:
undetectable		 4yv5B-3c7oA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 GLY A  22
ILE A  17
HIS A  19
LEU A  16
ILE A  36
 None
 0.98A 5d4uD-3c7oA:
undetectable		 5d4uD-3c7oA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 6 PHE A 468
PHE A 410
GLU A 359
VAL A 358
 None
None
CA  A 488 (-3.4A)
None
 1.03A 5h4dA-3c7oA:
undetectable		 5h4dA-3c7oA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 7 HIS A  20
ILE A  65
VAL A  64
GLN A 384
 None
 1.25A 5kkzC-3c7oA:
0.7
5kkzE-3c7oA:
undetectable		 5kkzC-3c7oA:
18.59
5kkzE-3c7oA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 7 ILE A  65
VAL A  64
GLN A 384
HIS A  20
 None
 1.27A 5kkzK-3c7oA:
undetectable
5kkzQ-3c7oA:
0.8		 5kkzK-3c7oA:
22.03
5kkzQ-3c7oA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 7 HIS A  20
ILE A  65
VAL A  64
GLN A 384
 None
 1.26A 5kkzM-3c7oA:
0.8
5kkzO-3c7oA:
undetectable		 5kkzM-3c7oA:
18.59
5kkzO-3c7oA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		3 / 3 HIS A 248
LYS A 252
PHE A 222
 None
 1.21A 5klaA-3c7oA:
undetectable		 5klaA-3c7oA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		4 / 5 HIS A 291
SER A 239
TYR A 238
GLY A 228
 None
 1.27A 5yodH-3c7oA:
undetectable		 5yodH-3c7oA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3c7o ENDO-1,4-BETA-XYLANA
SE
(Bacillus
subtilis) 		5 / 12 GLY A 205
ASP A 171
GLY A 172
GLY A 174
ALA A 106
 None
 0.93A 6nj9K-3c7oA:
undetectable		 6nj9K-3c7oA:
23.19