SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 11 GLU A  66
ILE A  67
ALA A  71
ASP A  86
PRO A 110
 None
SO4  A 201 ( 4.9A)
None
SO4  A 201 (-4.4A)
None
 0.91A 2admB-3c85A:
5.3		 2admB-3c85A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 12 GLY A  42
GLY A  44
GLY A  49
ASP A  86
MET A 109
 None
None
None
SO4  A 201 (-4.4A)
None
 1.04A 2b25A-3c85A:
7.3		 2b25A-3c85A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 TYR A 156
SER A 157
GLN A 140
ILE A 134
 None
 0.91A 2xz5A-3c85A:
undetectable
2xz5B-3c85A:
undetectable		 2xz5A-3c85A:
21.03
2xz5B-3c85A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 8 TYR A 156
SER A 157
GLN A 140
ILE A 134
 None
 0.93A 2xz5B-3c85A:
undetectable
2xz5E-3c85A:
undetectable		 2xz5B-3c85A:
21.03
2xz5E-3c85A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 12 GLY A  42
GLU A  66
ILE A  67
ALA A  87
LEU A 106
 None
None
SO4  A 201 ( 4.9A)
None
None
 1.19A 3ckkA-3c85A:
8.3		 3ckkA-3c85A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		6 / 12 GLY A  42
GLY A  44
GLU A  66
ILE A  67
ARG A  68
ALA A  87
 None
None
None
SO4  A 201 ( 4.9A)
None
None
 1.23A 3ckkA-3c85A:
8.3		 3ckkA-3c85A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		3 / 3 LEU A 141
GLU A 158
ILE A 155
 None
 0.54A 3czhA-3c85A:
undetectable		 3czhA-3c85A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 11 GLY A  42
GLY A  44
ILE A  65
ASP A  86
ALA A  87
 None
None
None
SO4  A 201 (-4.4A)
None
 1.04A 3dxyA-3c85A:
7.7		 3dxyA-3c85A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 11 GLY A  42
ILE A  65
GLU A  66
ASP A  86
ALA A  87
 None
None
None
SO4  A 201 (-4.4A)
None
 0.90A 3dxyA-3c85A:
7.7		 3dxyA-3c85A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 12 GLY A  42
GLY A  44
GLU A  66
ASP A  86
ALA A  87
 None
None
None
SO4  A 201 (-4.4A)
None
 0.78A 3fuuA-3c85A:
7.1		 3fuuA-3c85A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		6 / 11 GLY A  42
GLY A  44
GLU A  66
ILE A  67
ASP A  86
ALA A  87
 None
None
None
SO4  A 201 ( 4.9A)
SO4  A 201 (-4.4A)
None
 0.51A 3grvA-3c85A:
6.9		 3grvA-3c85A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		6 / 12 GLY A  42
GLY A  44
GLU A  66
ILE A  67
ASP A  86
ALA A  87
 None
None
None
SO4  A 201 ( 4.9A)
SO4  A 201 (-4.4A)
None
 0.55A 3gryA-3c85A:
6.9		 3gryA-3c85A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 5 ILE A  31
PHE A  92
ASP A  91
GLU A  94
 None
 0.89A 3kp6A-3c85A:
undetectable
3kp6B-3c85A:
undetectable		 3kp6A-3c85A:
20.00
3kp6B-3c85A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  41
ASN A 115
GLY A 114
TRP A  93
LEU A 122
 None
 1.25A 3medA-3c85A:
undetectable
3medB-3c85A:
undetectable		 3medA-3c85A:
16.38
3medB-3c85A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 ALA A  36
ASP A  52
GLY A  79
GLU A  78
 None
 0.78A 5bs8A-3c85A:
undetectable
5bs8C-3c85A:
undetectable
5bs8D-3c85A:
3.0		 5bs8A-3c85A:
17.52
5bs8C-3c85A:
17.52
5bs8D-3c85A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 ALA A  36
ASP A  52
GLY A  79
GLU A  78
 None
 0.75A 5bs8A-3c85A:
undetectable
5bs8B-3c85A:
2.8
5bs8C-3c85A:
undetectable		 5bs8A-3c85A:
17.52
5bs8B-3c85A:
23.64
5bs8C-3c85A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 ALA A  36
ASP A  52
GLY A  79
GLU A  78
 None
 0.77A 5btdA-3c85A:
undetectable
5btdB-3c85A:
2.7
5btdC-3c85A:
undetectable		 5btdA-3c85A:
17.52
5btdB-3c85A:
23.64
5btdC-3c85A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 ALA A  36
ASP A  52
GLY A  79
GLU A  78
 None
 0.79A 5btdA-3c85A:
undetectable
5btdC-3c85A:
undetectable
5btdD-3c85A:
undetectable		 5btdA-3c85A:
17.52
5btdC-3c85A:
17.52
5btdD-3c85A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 ALA A  36
ASP A  52
GLY A  79
GLU A  78
 None
 0.80A 5btgA-3c85A:
undetectable
5btgC-3c85A:
undetectable
5btgD-3c85A:
3.0		 5btgA-3c85A:
17.52
5btgC-3c85A:
17.52
5btgD-3c85A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3c85 PUTATIVE
GLUTATHIONE-REGULATE
D POTASSIUM-EFFLUX
SYSTEM PROTEIN KEFB
(Vibrio
parahaemolyticus) 		4 / 7 GLY A  42
GLY A  44
GLU A  66
ASP A  86
 None
None
None
SO4  A 201 (-4.4A)
 0.64A 5ergB-3c85A:
7.9		 5ergB-3c85A:
21.59