SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c8c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 8 VAL A 225
HIS A 258
VAL A 269
GLU A 250
 None
 1.14A 1jtvA-3c8cA:
undetectable		 1jtvA-3c8cA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		3 / 3 ILE A 198
ILE A 135
LEU A 179
 None
 0.52A 2prgA-3c8cA:
undetectable		 2prgA-3c8cA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		3 / 3 PRO A 149
GLY A 127
TYR A 155
 None
 0.56A 2vouA-3c8cA:
undetectable		 2vouA-3c8cA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		3 / 3 PRO A 149
GLY A 127
TYR A 155
 None
 0.58A 2vouB-3c8cA:
undetectable		 2vouB-3c8cA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		3 / 3 PRO A 149
GLY A 127
TYR A 155
 None
 0.58A 2vouC-3c8cA:
undetectable		 2vouC-3c8cA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 158
GLY A 162
LEU A 164
GLY A 196
SER A 197
 None
 1.10A 3g2oA-3c8cA:
undetectable		 3g2oA-3c8cA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 158
GLY A 162
LEU A 164
GLY A 196
SER A 197
 None
 1.09A 3g2oB-3c8cA:
undetectable		 3g2oB-3c8cA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 8 SER A 181
PHE A 199
ASP A 172
PRO A 149
 ALA  A 502 ( 4.5A)
ALA  A 502 (-4.0A)
ALA  A 502 (-3.9A)
None
 1.10A 3jq7B-3c8cA:
undetectable		 3jq7B-3c8cA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 7 LEU A 195
ASP A 188
SER A 189
GLU A 104
 None
 1.32A 4aq7A-3c8cA:
2.4		 4aq7A-3c8cA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 8 ASP A 273
ALA A  82
SER A 272
ASP A  75
 None
 1.08A 4l7iB-3c8cA:
undetectable		 4l7iB-3c8cA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 6 ILE A 253
GLY A 282
VAL A 284
HIS A 258
 None
 1.06A 4oltA-3c8cA:
undetectable		 4oltA-3c8cA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 6 ILE A 253
GLY A 282
VAL A 284
HIS A 258
 None
 1.04A 4oltB-3c8cA:
undetectable		 4oltB-3c8cA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 8 LEU A 195
GLY A 196
GLU A 129
ALA A 161
 None
 0.76A 4rjdA-3c8cA:
undetectable
4rjdB-3c8cA:
undetectable		 4rjdA-3c8cA:
16.07
4rjdB-3c8cA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3c8c METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Vibrio
cholerae) 		4 / 7 GLU A 227
ILE A 253
LYS A 252
VAL A 255
 None
 1.20A 4tvtA-3c8cA:
undetectable		 4tvtA-3c8cA:
22.83