SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c8g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3c8g PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Shigella
flexneri) 		5 / 12 LEU B  13
ILE B  29
GLN B  36
ILE B  74
LEU B  71
 None
 1.19A 5y2tB-3c8gB:
undetectable		 5y2tB-3c8gB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 3c8g PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Shigella
flexneri) 		5 / 10 VAL B 119
MET B  23
LEU B  30
ILE B  88
THR B 163
 None
 1.40A 6d9hR-3c8gB:
2.9		 6d9hR-3c8gB:
22.22