SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c8j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJD_A_C2FA314_0 (UNCHARACTERIZED PROTEIN)	3c8j	NATURAL KILLER CELL RECEPTOR LY49C (Mus musculus)	5 / 12	TYR A 151 VAL A 172 GLY A 171 ILE A 211 ILE A 197	None	0.91A	3ijdA-3c8jA: undetectable	3ijdA-3c8jA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LM8_A_VIBA223_1 (THIAMINE PYROPHOSPHOKINASE)	3c8j	NATURAL KILLER CELL RECEPTOR LY49C (Mus musculus)	4 / 7	TYR A 195 LEU A 175 LEU A 186 SER A 236	None	1.05A	3lm8A-3c8jA: undetectable 3lm8C-3c8jA: undetectable	3lm8A-3c8jA: 18.80 3lm8C-3c8jA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LM8_D_VIBD223_1 (THIAMINE PYROPHOSPHOKINASE)	3c8j	NATURAL KILLER CELL RECEPTOR LY49C (Mus musculus)	4 / 8	TYR A 195 LEU A 175 LEU A 186 SER A 236	None	1.02A	3lm8B-3c8jA: undetectable 3lm8D-3c8jA: undetectable	3lm8B-3c8jA: 18.80 3lm8D-3c8jA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ESM_A_PZEA307_1 (MATRIX METALLOPROTEINASE-9, MATRIX METALLOPROTEINASE-9)	3c8j	NATURAL KILLER CELL RECEPTOR LY49C (Mus musculus)	3 / 3	TYR A 151 HIS A 189 PHE A 185	None	1.01A	6esmA-3c8jA: undetectable	6esmA-3c8jA: 16.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IJD_A_C2FA314_0","UNCHARACTERIZED PROTEIN","3c8j","NATURAL KILLER CELL RECEPTOR LY49C","Mus musculus",5,"TYR A 151;VAL A 172;GLY A 171;ILE A 211;ILE A 197","None","0.91A","3ijdA-3c8jA:undetectable","3ijdA-3c8jA:20.78"],["3LM8_A_VIBA223_1","THIAMINE PYROPHOSPHOKINASE;THIAMINE PYROPHOSPHOKINASE","3c8j","NATURAL KILLER CELL RECEPTOR LY49C","Mus musculus",4,"TYR A 195;LEU A 175;LEU A 186;SER A 236","None","1.05A","3lm8A-3c8jA:undetectable;3lm8C-3c8jA:undetectable","3lm8A-3c8jA:18.80;3lm8C-3c8jA:18.80"],["3LM8_D_VIBD223_1","THIAMINE PYROPHOSPHOKINASE;THIAMINE PYROPHOSPHOKINASE","3c8j","NATURAL KILLER CELL RECEPTOR LY49C","Mus musculus",4,"TYR A 195;LEU A 175;LEU A 186;SER A 236","None","1.02A","3lm8B-3c8jA:undetectable;3lm8D-3c8jA:undetectable","3lm8B-3c8jA:18.80;3lm8D-3c8jA:18.80"],["6ESM_A_PZEA307_1","MATRIX METALLOPROTEINASE-9,MATRIX METALLOPROTEINASE-9","3c8j","NATURAL KILLER CELL RECEPTOR LY49C","Mus musculus",3,"TYR A 151;HIS A 189;PHE A 185","None","1.01A","6esmA-3c8jA:undetectable","6esmA-3c8jA:16.58"]]