SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 8 ILE A  55
PHE A  78
HIS A  49
VAL A 116
 IMD  A 125 ( 4.6A)
IMD  A 125 ( 4.6A)
None
None
 0.81A 1fslA-3c8lA:
undetectable		 1fslA-3c8lA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 MET A  12
ALA A 110
VAL A  92
GLY A  13
ILE A  14
 None
None
None
CL  A 124 ( 3.7A)
CL  A 124 (-4.4A)
 1.30A 2dcfA-3c8lA:
undetectable		 2dcfA-3c8lA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		6 / 12 GLY A  11
ALA A 112
VAL A  85
GLY A  89
ILE A 109
PRO A  21
 None
 1.39A 2q5kB-3c8lA:
undetectable		 2q5kB-3c8lA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 9 ALA A 112
VAL A  59
GLY A  89
ILE A  14
ALA A  25
 None
None
None
CL  A 124 (-4.4A)
None
 0.85A 2z0yA-3c8lA:
undetectable		 2z0yA-3c8lA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 9 ALA A 112
VAL A  59
GLY A  89
ILE A  14
ALA A  25
 None
None
None
CL  A 124 (-4.4A)
None
 0.93A 2z0yB-3c8lA:
undetectable		 2z0yB-3c8lA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 8 VAL A  67
GLY A  13
ILE A  14
PRO A  62
 None
CL  A 124 ( 3.7A)
CL  A 124 (-4.4A)
None
 0.72A 3nu9A-3c8lA:
undetectable		 3nu9A-3c8lA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 VAL A  29
ALA A 113
ILE A   8
LEU A  38
ILE A  33
 None
None
None
IMD  A 125 (-4.6A)
IMD  A 125 (-3.7A)
 1.18A 3qfxA-3c8lA:
undetectable		 3qfxA-3c8lA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 VAL A  29
ALA A 113
ILE A   8
LEU A  38
ILE A  33
 None
None
None
IMD  A 125 (-4.6A)
IMD  A 125 (-3.7A)
 1.14A 3qfxB-3c8lA:
undetectable		 3qfxB-3c8lA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNM_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 GLY A  94
ASP A 102
HIS A  17
GLN A  16
ILE A  14
 None
None
None
None
CL  A 124 (-4.4A)
 1.45A 4ynmA-3c8lA:
undetectable		 4ynmA-3c8lA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 GLU A  65
ALA A  24
ALA A  25
VAL A  29
GLY A  89
 None
 0.80A 5igjA-3c8lA:
undetectable		 5igjA-3c8lA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3c8l FTSZ-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 GLU A  65
ALA A  24
ALA A  25
VAL A  29
GLY A  89
 None
 0.81A 5igtA-3c8lA:
undetectable		 5igtA-3c8lA:
19.14