SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3c8u FRUCTOKINASE
(Ruegeria
sp.
TM1040) 		4 / 5 GLY A  59
HIS A  92
ASP A 142
ASP A  83
 None
 1.16A 2oxtB-3c8uA:
undetectable		 2oxtB-3c8uA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 3c8u FRUCTOKINASE
(Ruegeria
sp.
TM1040) 		4 / 5 ILE A 193
PRO A  79
VAL A 125
PHE A  87
 None
 1.12A 2ygnA-3c8uA:
undetectable		 2ygnA-3c8uA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3c8u FRUCTOKINASE
(Ruegeria
sp.
TM1040) 		4 / 7 LEU A  45
VAL A 125
VAL A  10
LEU A  94
 None
 0.87A 3rgfA-3c8uA:
undetectable		 3rgfA-3c8uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3c8u FRUCTOKINASE
(Ruegeria
sp.
TM1040) 		4 / 6 ARG A  75
GLY A  77
THR A  81
GLU A  80
 None
 1.11A 5ny7A-3c8uA:
undetectable		 5ny7A-3c8uA:
24.23