SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.87A 1ddrA-3c9fA:
undetectable		 1ddrA-3c9fA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.95A 1ddsA-3c9fA:
undetectable		 1ddsA-3c9fA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 ASP A 108
ASP A  72
ASP A 136
 None
 0.80A 1eizA-3c9fA:
undetectable		 1eizA-3c9fA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 ASP A 108
ASP A  72
ASP A 136
 None
 0.78A 1ej0A-3c9fA:
undetectable		 1ej0A-3c9fA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 11 GLY A 388
ARG A 391
PHE A 410
ASN A 412
PHE A 521
 None
FMT  A 607 (-2.7A)
None
None
None
 0.98A 1ho5A-3c9fA:
25.6		 1ho5A-3c9fA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 10 GLY A 388
ARG A 391
PHE A 410
ASN A 412
PHE A 521
 None
FMT  A 607 (-2.7A)
None
None
None
 0.85A 1ho5B-3c9fA:
25.3		 1ho5B-3c9fA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 LEU A  75
VAL A 274
GLY A 275
TYR A 107
 None
 0.93A 1jlbA-3c9fA:
undetectable		 1jlbA-3c9fA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 LEU A  75
VAL A 274
GLY A 275
TYR A 107
 None
 1.05A 1jlfA-3c9fA:
undetectable
1jlfB-3c9fA:
undetectable		 1jlfA-3c9fA:
23.31
1jlfB-3c9fA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 11 ASP A 144
ASN A 142
GLY A 175
THR A 111
GLY A 156
 None
 1.49A 1jr1A-3c9fA:
undetectable		 1jr1A-3c9fA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 7 LEU A  75
VAL A 274
GLY A 275
TYR A 107
 None
 0.88A 1lweA-3c9fA:
undetectable		 1lweA-3c9fA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 ASP A  80
HIS A 115
HIS A  36
 ZN  A 601 ( 2.7A)
FMT  A 607 (-4.0A)
None
 0.61A 1oe1A-3c9fA:
undetectable		 1oe1A-3c9fA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 ASP A  80
HIS A 115
HIS A  36
 ZN  A 601 ( 2.7A)
FMT  A 607 (-4.0A)
None
 0.60A 1oe3A-3c9fA:
undetectable		 1oe3A-3c9fA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 7 ILE A 390
GLY A 388
PRO A 409
PHE A 410
 None
 0.99A 1oniG-3c9fA:
undetectable
1oniI-3c9fA:
undetectable		 1oniG-3c9fA:
14.03
1oniI-3c9fA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 LEU A  75
VAL A 274
GLY A 275
TYR A 107
 None
 0.86A 1s1xA-3c9fA:
undetectable		 1s1xA-3c9fA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.90A 1tdrA-3c9fA:
undetectable		 1tdrA-3c9fA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 9 HIS A 217
HIS A 249
PHE A 180
ASP A  80
TYR A 118
 ZN  A 601 (-3.5A)
ZN  A 601 ( 3.4A)
None
ZN  A 601 ( 2.7A)
None
 1.46A 1zz1D-3c9fA:
undetectable		 1zz1D-3c9fA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.99A 2d0kB-3c9fA:
undetectable		 2d0kB-3c9fA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 TYR A 395
ASP A 393
TYR A 352
HIS A 357
 None
 1.31A 2ha2A-3c9fA:
undetectable		 2ha2A-3c9fA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 TYR A 395
ASP A 393
TYR A 352
HIS A 357
 None
 1.31A 2ha2B-3c9fA:
undetectable		 2ha2B-3c9fA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 PHE A 405
GLY A  86
LEU A 394
ILE A 390
LEU A 553
 None
 1.06A 2nxeB-3c9fA:
undetectable		 2nxeB-3c9fA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ASP A  77
LEU A 110
THR A 129
LEU A 155
THR A  35
 None
 1.18A 2oipC-3c9fA:
undetectable		 2oipC-3c9fA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 SER A  98
HIS A  42
ASP A 393
 None
 0.79A 2oxtA-3c9fA:
undetectable		 2oxtA-3c9fA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 SER A  98
ASP A 402
ASP A  89
 None
 0.75A 2plwA-3c9fA:
undetectable		 2plwA-3c9fA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 7 HIS A 249
HIS A  36
ARG A 391
TYR A 118
 ZN  A 601 ( 3.4A)
None
FMT  A 607 (-2.7A)
None
 1.44A 2vmyA-3c9fA:
undetectable
2vmyB-3c9fA:
undetectable		 2vmyA-3c9fA:
19.21
2vmyB-3c9fA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 HIS A  36
ASP A  80
HIS A 251
ASP A  34
 None
ZN  A 601 ( 2.7A)
None
ZN  A 601 ( 4.6A)
 1.11A 2xadA-3c9fA:
2.1		 2xadA-3c9fA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 HIS A  36
ASP A  80
HIS A 251
ASP A  34
 None
ZN  A 601 ( 2.7A)
None
ZN  A 601 ( 4.6A)
 1.11A 2xadB-3c9fA:
undetectable		 2xadB-3c9fA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 HIS A  36
ASP A  80
HIS A 251
ASP A  34
 None
ZN  A 601 ( 2.7A)
None
ZN  A 601 ( 4.6A)
 1.09A 2xadC-3c9fA:
2.0		 2xadC-3c9fA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 HIS A  36
ASP A  80
HIS A 251
ASP A  34
 None
ZN  A 601 ( 2.7A)
None
ZN  A 601 ( 4.6A)
 1.10A 2xadD-3c9fA:
undetectable		 2xadD-3c9fA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 GLY A 275
TYR A 298
SER A 267
 None
 0.72A 2xatA-3c9fA:
undetectable		 2xatA-3c9fA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 ASP A  80
HIS A 115
HIS A  36
 ZN  A 601 ( 2.7A)
FMT  A 607 (-4.0A)
None
 0.62A 2xxgA-3c9fA:
undetectable		 2xxgA-3c9fA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 ASP A  80
HIS A 115
HIS A  36
 ZN  A 601 ( 2.7A)
FMT  A 607 (-4.0A)
None
 0.62A 2xxgC-3c9fA:
undetectable		 2xxgC-3c9fA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 10 THR A  33
GLY A 248
GLY A  79
HIS A  36
PRO A 445
 None
None
None
None
FMT  A 607 ( 4.6A)
 1.42A 2y7wB-3c9fA:
undetectable		 2y7wB-3c9fA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 PHE A 410
ASN A 412
PHE A 521
 None
 0.90A 2zbuD-3c9fA:
undetectable		 2zbuD-3c9fA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 TYR A 348
ASN A 347
LYS A 396
PRO A 398
 None
 1.43A 3bjwD-3c9fA:
undetectable		 3bjwD-3c9fA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 THR A  32
THR A  33
THR A  35
HIS A 217
LEU A 110
 None
None
None
ZN  A 601 (-3.5A)
None
 1.22A 3gwxA-3c9fA:
undetectable		 3gwxA-3c9fA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 SER A 250
ASP A  34
ASP A 254
 None
ZN  A 601 ( 4.6A)
None
 0.74A 3iv6A-3c9fA:
undetectable		 3iv6A-3c9fA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 SER A 250
ASP A  34
ASP A 254
 None
ZN  A 601 ( 4.6A)
None
 0.79A 3iv6C-3c9fA:
undetectable		 3iv6C-3c9fA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 11 LEU A 177
ASP A  80
PHE A 178
HIS A 217
LEU A 117
 None
ZN  A 601 ( 2.7A)
None
ZN  A 601 (-3.5A)
None
 1.41A 3o94B-3c9fA:
undetectable		 3o94B-3c9fA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 TYR A 228
ASP A 259
ASP A 240
 None
 0.82A 3ou6B-3c9fA:
undetectable		 3ou6B-3c9fA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 GLY A 264
THR A 263
GLN A 244
THR A 277
 None
 0.71A 3rglA-3c9fA:
undetectable		 3rglA-3c9fA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 SER A  57
PHE A 306
LYS A 307
 None
 0.93A 3u88A-3c9fA:
undetectable		 3u88A-3c9fA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 7 HIS A 217
ASP A  83
HIS A 251
HIS A  82
 ZN  A 601 (-3.5A)
None
None
None
 1.33A 3zodA-3c9fA:
undetectable		 3zodA-3c9fA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.93A 4dfrA-3c9fA:
undetectable		 4dfrA-3c9fA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 9 ASN A 386
GLY A 388
ARG A 391
PHE A 410
PHE A 521
 None
None
FMT  A 607 (-2.7A)
None
None
 0.86A 4h2fA-3c9fA:
14.0		 4h2fA-3c9fA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 SER A 262
ASP A 259
GLN A 232
 None
 0.90A 4oltA-3c9fA:
undetectable
4oltB-3c9fA:
undetectable		 4oltA-3c9fA:
17.00
4oltB-3c9fA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 1.00A 4pthA-3c9fA:
undetectable		 4pthA-3c9fA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 1.01A 4qlgB-3c9fA:
undetectable		 4qlgB-3c9fA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 GLN A 232
SER A 262
ASP A 259
 None
 0.86A 4qwpA-3c9fA:
undetectable
4qwpB-3c9fA:
undetectable		 4qwpA-3c9fA:
16.85
4qwpB-3c9fA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 5 TYR A 352
TYR A 474
GLU A 272
GLN A  45
 None
 1.31A 4qztB-3c9fA:
undetectable		 4qztB-3c9fA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 11 LEU A 261
GLN A 244
HIS A  31
VAL A 279
THR A 277
 None
 1.31A 4uuuA-3c9fA:
undetectable
4uuuB-3c9fA:
undetectable		 4uuuA-3c9fA:
14.00
4uuuB-3c9fA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.95A 4x5fA-3c9fA:
undetectable		 4x5fA-3c9fA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.96A 4x5fB-3c9fA:
undetectable		 4x5fB-3c9fA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 0.95A 4x5gB-3c9fA:
undetectable		 4x5gB-3c9fA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 220
ASP A 485
THR A 476
ILE A 252
ASP A 449
 None
 1.44A 4xe0A-3c9fA:
undetectable		 4xe0A-3c9fA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 SER A 440
HIS A 217
HIS A 249
PHE A 180
ASP A  80
 None
ZN  A 601 (-3.5A)
ZN  A 601 ( 3.4A)
None
ZN  A 601 ( 2.7A)
 1.48A 5eenB-3c9fA:
undetectable		 5eenB-3c9fA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 HIS A 217
HIS A 249
PHE A 180
ASP A  80
TYR A 118
 ZN  A 601 (-3.5A)
ZN  A 601 ( 3.4A)
None
ZN  A 601 ( 2.7A)
None
 1.49A 5ef8A-3c9fA:
undetectable		 5ef8A-3c9fA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 GLY A 248
TYR A  39
ILE A 328
PHE A 301
THR A  59
 None
 1.26A 5eslA-3c9fA:
undetectable		 5eslA-3c9fA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 GLN A 125
LEU A 177
ILE A 220
GLY A 247
THR A  33
 None
 1.14A 5fsaB-3c9fA:
undetectable		 5fsaB-3c9fA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 6 ALA A 193
GLN A 229
VAL A 230
TYR A 233
 None
 1.04A 5i8fA-3c9fA:
undetectable		 5i8fA-3c9fA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 TYR A 352
TYR A  48
GLN A  45
 None
 1.08A 5jsdA-3c9fA:
undetectable
5jsdB-3c9fA:
undetectable		 5jsdA-3c9fA:
22.10
5jsdB-3c9fA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		3 / 3 TYR A 352
TYR A  48
GLN A  45
 None
 1.09A 5jsdB-3c9fA:
undetectable
5jsdC-3c9fA:
undetectable		 5jsdB-3c9fA:
22.10
5jsdC-3c9fA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 4 ASP A  80
HIS A 217
HIS A 249
HIS A 115
 ZN  A 601 ( 2.7A)
ZN  A 601 (-3.5A)
ZN  A 601 ( 3.4A)
FMT  A 607 (-4.0A)
 1.45A 5ncdD-3c9fA:
undetectable		 5ncdD-3c9fA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 6 ASP A  80
HIS A  36
HIS A 251
HIS A 217
 ZN  A 601 ( 2.7A)
None
None
ZN  A 601 (-3.5A)
 1.00A 5nelB-3c9fA:
undetectable
5nelC-3c9fA:
undetectable		 5nelB-3c9fA:
16.79
5nelC-3c9fA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 8 VAL A 492
TYR A 392
GLN A  45
HIS A  36
 None
 0.95A 5nu7A-3c9fA:
undetectable		 5nu7A-3c9fA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 PRO A 409
ILE A 385
ILE A 369
LEU A 373
THR A 372
 None
 1.27A 5tiwB-3c9fA:
undetectable		 5tiwB-3c9fA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 12 ILE A 101
THR A  91
ILE A  90
LEU A 337
ARG A 332
 None
 1.01A 5ujxB-3c9fA:
undetectable		 5ujxB-3c9fA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		5 / 11 HIS A 217
HIS A 249
HIS A 251
HIS A 115
PRO A 409
 ZN  A 601 (-3.5A)
ZN  A 601 ( 3.4A)
None
FMT  A 607 (-4.0A)
None
 1.48A 5z0fA-3c9fA:
undetectable
5z0fB-3c9fA:
undetectable		 5z0fA-3c9fA:
10.22
5z0fB-3c9fA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3c9f 5'-NUCLEOTIDASE
(Candida
albicans) 		4 / 7 THR A  35
ILE A 101
THR A  99
TYR A 107
 None
 0.96A 5zsfA-3c9fA:
2.3
5zsfB-3c9fA:
undetectable		 5zsfA-3c9fA:
8.87
5zsfB-3c9fA:
8.87