SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3c9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.11A 1dz4A-3c9hA:
undetectable
1dz4A-3c9hA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.08A 1dz4B-3c9hA:
undetectable
1dz4B-3c9hA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
3 / 3 PHE A 139
TYR A 257
PRO A 254
None
1.14A 1mcnA-3c9hA:
undetectable
1mcnB-3c9hA:
undetectable
1mcnP-3c9hA:
undetectable
1mcnA-3c9hA:
20.48
1mcnB-3c9hA:
20.48
1mcnP-3c9hA:
0.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 5 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.13A 1t88B-3c9hA:
undetectable
1t88B-3c9hA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 TYR A 280
THR A  48
TYR A  65
LEU A  46
None
1.44A 1uw6A-3c9hA:
undetectable
1uw6B-3c9hA:
undetectable
1uw6A-3c9hA:
19.89
1uw6B-3c9hA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 TYR A 280
THR A  48
TYR A  65
LEU A  46
None
1.46A 1uw6D-3c9hA:
undetectable
1uw6E-3c9hA:
undetectable
1uw6D-3c9hA:
19.89
1uw6E-3c9hA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 TYR A 280
THR A  48
TYR A  65
LEU A  46
None
1.45A 1uw6G-3c9hA:
undetectable
1uw6H-3c9hA:
undetectable
1uw6G-3c9hA:
19.89
1uw6H-3c9hA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 TYR A 280
THR A  48
TYR A  65
LEU A  46
None
1.45A 1uw6P-3c9hA:
undetectable
1uw6Q-3c9hA:
undetectable
1uw6P-3c9hA:
19.89
1uw6Q-3c9hA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
5 / 12 LEU A 253
SER A 216
LEU A 220
LEU A 235
THR A 258
None
CIT  A 402 (-4.0A)
None
None
None
1.40A 1ya3B-3c9hA:
undetectable
1ya3B-3c9hA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A  24
THR A  48
GLU A  52
GLU A  44
None
1.41A 2dttB-3c9hA:
undetectable
2dttC-3c9hA:
undetectable
2dttB-3c9hA:
14.40
2dttC-3c9hA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 5 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.10A 2m56A-3c9hA:
undetectable
2m56A-3c9hA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.19A 2obvA-3c9hA:
undetectable
2obvA-3c9hA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.17A 2p02A-3c9hA:
undetectable
2p02A-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 VAL A  37
ASN A 273
TYR A  39
GLU A  80
None
0.98A 3q5sA-3c9hA:
undetectable
3q5sA-3c9hA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 ASP A  43
LEU A  46
ALA A 239
LEU A 220
MG  A 401 ( 3.2A)
None
None
None
1.11A 3rozA-3c9hA:
undetectable
3rozA-3c9hA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.12A 3wrhE-3c9hA:
undetectable
3wrhE-3c9hA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.10A 4g3rB-3c9hA:
undetectable
4g3rB-3c9hA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.16A 4kkyX-3c9hA:
undetectable
4kkyX-3c9hA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.20A 4kttC-3c9hA:
undetectable
4kttC-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 5 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.12A 4l49A-3c9hA:
undetectable
4l49A-3c9hA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 6 PHE A 146
LEU A 162
VAL A 169
VAL A 223
None
1.12A 4l4cA-3c9hA:
undetectable
4l4cA-3c9hA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 7 TYR A 280
GLN A  20
LEU A  69
THR A 215
None
None
CIT  A 402 (-3.9A)
CIT  A 402 (-4.0A)
1.12A 4mbsA-3c9hA:
undetectable
4mbsA-3c9hA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.19A 4ndnA-3c9hA:
undetectable
4ndnA-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 7 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.17A 4ndnC-3c9hA:
undetectable
4ndnC-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 7 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.27A 4odjA-3c9hA:
undetectable
4odjA-3c9hA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.15A 5a1iA-3c9hA:
undetectable
5a1iA-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 7 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.15A 5a1iA-3c9hA:
undetectable
5a1iA-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
3 / 3 ILE A 345
MET A 205
ASP A 177
None
0.72A 5h2uA-3c9hA:
undetectable
5h2uA-3c9hA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.16A 6fbnB-3c9hA:
undetectable
6fbnB-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.18A 6fboA-3c9hA:
undetectable
6fboA-3c9hA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.18A 6fcbA-3c9hA:
undetectable
6fcbA-3c9hA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 8 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.18A 6fcdA-3c9hA:
undetectable
6fcdA-3c9hA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum)
4 / 7 PRO A 254
ASP A 256
SER A 200
PHE A 195
None
1.17A 6g6rA-3c9hA:
undetectable
6g6rA-3c9hA:
22.82