SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ca9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3ca9 DEOXYURIDINE
TRIPHOSPHATASE
(Paramecium
bursaria
Chlorella
virus
IL3A) 		3 / 3 ARG A 106
ARG A  63
ILE A 101
 None
 0.74A 1uobA-3ca9A:
undetectable		 1uobA-3ca9A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3ca9 DEOXYURIDINE
TRIPHOSPHATASE
(Paramecium
bursaria
Chlorella
virus
IL3A) 		4 / 8 ARG A  51
ILE A  50
LEU A   9
GLY A  47
 None
 0.91A 2tsrB-3ca9A:
undetectable		 2tsrB-3ca9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3ca9 DEOXYURIDINE
TRIPHOSPHATASE
(Paramecium
bursaria
Chlorella
virus
IL3A) 		4 / 6 ARG A  63
ILE A  60
VAL A  89
LEU A  91
 None
DUD  A 777 ( 4.9A)
None
None
 0.94A 4em2A-3ca9A:
undetectable		 4em2A-3ca9A:
21.84