SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3cad LECTIN-RELATED NK
CELL RECEPTOR LY49G1
(Mus
musculus) 		3 / 3 LEU A 240
MET A 233
MET A 155
 None
 1.01A 2vavF-3cadA:
undetectable		 2vavF-3cadA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3cad LECTIN-RELATED NK
CELL RECEPTOR LY49G1
(Mus
musculus) 		5 / 12 LEU A 189
GLU A 182
LEU A 235
ILE A 252
SER A 195
 None
 1.31A 2ydoA-3cadA:
undetectable		 2ydoA-3cadA:
14.52