SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3cah AGGLUTININ II
(Sambucus
nigra) 		4 / 6 ASP A 114
LEU A  97
VAL A  98
ILE A  91
 NAG  A 258 ( 3.7A)
None
None
None
 0.98A 1s9qA-3cahA:
undetectable		 1s9qA-3cahA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cah AGGLUTININ II
(Sambucus
nigra) 		5 / 9 GLY A 215
ASP A 214
VAL A 218
VAL A 225
GLN A 249
 None
 1.49A 3fi0R-3cahA:
undetectable		 3fi0R-3cahA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3cah AGGLUTININ II
(Sambucus
nigra) 		5 / 9 ASN A  78
LEU A  97
ALA A  58
SER A  65
ASN A  62
 None
 1.26A 3kp6B-3cahA:
undetectable		 3kp6B-3cahA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3cah AGGLUTININ II
(Sambucus
nigra) 		3 / 3 ILE A 238
ILE A 197
MET A 155
 None
 0.68A 5i9yA-3cahA:
undetectable		 5i9yA-3cahA:
22.43