SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3caw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		4 / 8 PHE A  93
LEU A 284
THR A 285
HIS A 286
 None
 1.03A 1azmA-3cawA:
undetectable		 1azmA-3cawA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		4 / 5 MET A 150
ALA A 146
ILE A 145
ASP A 117
 None
 0.97A 1upfC-3cawA:
2.5		 1upfC-3cawA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		3 / 3 GLY A 275
GLU A  97
ASP A 276
 None
 0.65A 2b25B-3cawA:
undetectable		 2b25B-3cawA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		4 / 6 LEU A  54
GLN A  71
GLU A  73
ILE A  72
 None
 1.05A 2fcnA-3cawA:
undetectable
2fcnB-3cawA:
undetectable		 2fcnA-3cawA:
12.19
2fcnB-3cawA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		3 / 3 LEU A  63
GLU A  73
ILE A  76
 None
 0.57A 3czhA-3cawA:
undetectable		 3czhA-3cawA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		4 / 6 THR A 323
GLN A  59
LEU A  60
GLU A  57
 None
 1.28A 4nc3A-3cawA:
undetectable		 4nc3A-3cawA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		5 / 11 LEU A  11
TYR A 289
PHE A 294
ASP A  44
VAL A 258
 None
 1.32A 5hjiA-3cawA:
undetectable		 5hjiA-3cawA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		3 / 3 GLU A 181
ARG A 153
TYR A 182
 None
 0.52A 5trqB-3cawA:
undetectable		 5trqB-3cawA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3caw O-SUCCINYLBENZOATE
SYNTHASE
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A 230
GLY A  28
ASP A  53
LEU A  60
LEU A  56
 None
 1.07A 5wwsA-3cawA:
undetectable		 5wwsA-3cawA:
23.41