SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1c9sA-3cb5A:
undetectable
1c9sK-3cb5A:
undetectable		 1c9sA-3cb5A:
9.95
1c9sK-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 1c9sA-3cb5A:
undetectable
1c9sB-3cb5A:
undetectable		 1c9sA-3cb5A:
9.95
1c9sB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.78A 1c9sI-3cb5A:
undetectable
1c9sJ-3cb5A:
undetectable		 1c9sI-3cb5A:
9.95
1c9sJ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1c9sL-3cb5A:
undetectable
1c9sM-3cb5A:
undetectable		 1c9sL-3cb5A:
9.95
1c9sM-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1c9sN-3cb5A:
undetectable
1c9sO-3cb5A:
undetectable		 1c9sN-3cb5A:
9.95
1c9sO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1c9sO-3cb5A:
undetectable
1c9sP-3cb5A:
undetectable		 1c9sO-3cb5A:
9.95
1c9sP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1c9sP-3cb5A:
undetectable
1c9sQ-3cb5A:
undetectable		 1c9sP-3cb5A:
9.95
1c9sQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1c9sQ-3cb5A:
undetectable
1c9sR-3cb5A:
undetectable		 1c9sQ-3cb5A:
9.95
1c9sR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1c9sS-3cb5A:
undetectable
1c9sT-3cb5A:
undetectable		 1c9sS-3cb5A:
9.95
1c9sT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 7 ALA A 187
THR A 426
THR A 414
SER A 191
 None
 0.81A 1c9sT-3cb5A:
undetectable
1c9sU-3cb5A:
undetectable		 1c9sT-3cb5A:
9.95
1c9sU-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.81A 1c9sU-3cb5A:
undetectable
1c9sV-3cb5A:
undetectable		 1c9sU-3cb5A:
9.95
1c9sV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 1c9sL-3cb5A:
undetectable
1c9sV-3cb5A:
undetectable		 1c9sL-3cb5A:
9.95
1c9sV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 4 ILE A 184
MET A 383
VAL A 371
GLY A 361
 None
 1.30A 1e06B-3cb5A:
undetectable		 1e06B-3cb5A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 5 LYS A 319
LEU A 340
GLU A 322
ALA A 315
 None
 1.04A 1eta1-3cb5A:
undetectable		 1eta1-3cb5A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 5 LYS A 319
LEU A 340
GLU A 322
ALA A 315
 None
 1.07A 1eta2-3cb5A:
undetectable		 1eta2-3cb5A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 6 LYS A 319
LEU A 340
GLU A 322
ALA A 315
 None
 1.00A 1etb1-3cb5A:
undetectable		 1etb1-3cb5A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 1gtfC-3cb5A:
undetectable
1gtfD-3cb5A:
undetectable		 1gtfC-3cb5A:
9.95
1gtfD-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 1gtfD-3cb5A:
undetectable
1gtfE-3cb5A:
undetectable		 1gtfD-3cb5A:
9.95
1gtfE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 1gtfJ-3cb5A:
undetectable
1gtfK-3cb5A:
undetectable		 1gtfJ-3cb5A:
9.95
1gtfK-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1gtfO-3cb5A:
undetectable
1gtfP-3cb5A:
undetectable		 1gtfO-3cb5A:
9.95
1gtfP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1gtfQ-3cb5A:
undetectable
1gtfR-3cb5A:
undetectable		 1gtfQ-3cb5A:
9.95
1gtfR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1gtfR-3cb5A:
undetectable
1gtfS-3cb5A:
undetectable		 1gtfR-3cb5A:
9.95
1gtfS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 1gtfS-3cb5A:
undetectable
1gtfT-3cb5A:
undetectable		 1gtfS-3cb5A:
9.95
1gtfT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1gtfU-3cb5A:
undetectable
1gtfV-3cb5A:
undetectable		 1gtfU-3cb5A:
9.95
1gtfV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 7 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.80A 1gtnA-3cb5A:
undetectable
1gtnK-3cb5A:
undetectable		 1gtnA-3cb5A:
9.95
1gtnK-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 8 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.93A 1gtnA-3cb5A:
undetectable
1gtnB-3cb5A:
undetectable		 1gtnA-3cb5A:
9.95
1gtnB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.97A 1gtnB-3cb5A:
undetectable
1gtnC-3cb5A:
undetectable		 1gtnB-3cb5A:
9.95
1gtnC-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.80A 1gtnE-3cb5A:
undetectable
1gtnF-3cb5A:
undetectable		 1gtnE-3cb5A:
9.95
1gtnF-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 1gtnH-3cb5A:
undetectable
1gtnI-3cb5A:
undetectable		 1gtnH-3cb5A:
9.95
1gtnI-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.94A 1gtnL-3cb5A:
undetectable
1gtnM-3cb5A:
undetectable		 1gtnL-3cb5A:
9.95
1gtnM-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.92A 1gtnM-3cb5A:
undetectable
1gtnN-3cb5A:
undetectable		 1gtnM-3cb5A:
9.95
1gtnN-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.94A 1gtnN-3cb5A:
undetectable
1gtnO-3cb5A:
undetectable		 1gtnN-3cb5A:
9.95
1gtnO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.80A 1gtnP-3cb5A:
undetectable
1gtnQ-3cb5A:
undetectable		 1gtnP-3cb5A:
9.95
1gtnQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.91A 1gtnR-3cb5A:
undetectable
1gtnS-3cb5A:
undetectable		 1gtnR-3cb5A:
9.95
1gtnS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.88A 1gtnS-3cb5A:
undetectable
1gtnT-3cb5A:
undetectable		 1gtnS-3cb5A:
9.95
1gtnT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.93A 1gtnT-3cb5A:
undetectable
1gtnU-3cb5A:
undetectable		 1gtnT-3cb5A:
9.95
1gtnU-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1gtnU-3cb5A:
undetectable
1gtnV-3cb5A:
undetectable		 1gtnU-3cb5A:
9.95
1gtnV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 12 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.92A 1gtnL-3cb5A:
undetectable
1gtnV-3cb5A:
undetectable		 1gtnL-3cb5A:
9.95
1gtnV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.80A 1utdB-3cb5A:
undetectable
1utdC-3cb5A:
undetectable		 1utdB-3cb5A:
9.95
1utdC-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
GLY A 295
 None
 0.95A 1utdE-3cb5A:
undetectable
1utdF-3cb5A:
undetectable		 1utdE-3cb5A:
9.95
1utdF-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.80A 1utdF-3cb5A:
undetectable
1utdG-3cb5A:
undetectable		 1utdF-3cb5A:
9.95
1utdG-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.80A 1utdJ-3cb5A:
undetectable
1utdK-3cb5A:
undetectable		 1utdJ-3cb5A:
9.95
1utdK-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1utdO-3cb5A:
undetectable
1utdP-3cb5A:
undetectable		 1utdO-3cb5A:
9.95
1utdP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 1utdP-3cb5A:
undetectable
1utdQ-3cb5A:
undetectable		 1utdP-3cb5A:
9.95
1utdQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 1utdQ-3cb5A:
undetectable
1utdR-3cb5A:
undetectable		 1utdQ-3cb5A:
9.95
1utdR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
GLY A 295
 None
 0.97A 1utdS-3cb5A:
undetectable
1utdT-3cb5A:
undetectable		 1utdS-3cb5A:
9.95
1utdT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 1utdS-3cb5A:
undetectable
1utdT-3cb5A:
undetectable		 1utdS-3cb5A:
9.95
1utdT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.94A 1utdT-3cb5A:
undetectable
1utdU-3cb5A:
undetectable		 1utdT-3cb5A:
9.95
1utdU-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 1utdU-3cb5A:
undetectable
1utdV-3cb5A:
undetectable		 1utdU-3cb5A:
9.95
1utdV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.98A 1utdL-3cb5A:
undetectable
1utdV-3cb5A:
undetectable		 1utdL-3cb5A:
9.95
1utdV-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 MET A 222
TRP A 249
THR A 252
CYH A 281
 None
 1.32A 1uw6P-3cb5A:
undetectable
1uw6T-3cb5A:
undetectable		 1uw6P-3cb5A:
19.27
1uw6T-3cb5A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 414
GLY A 295
GLN A 317
ILE A 415
PHE A 321
 None
 1.13A 2akeA-3cb5A:
undetectable		 2akeA-3cb5A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 414
GLY A 295
GLN A 317
ILE A 415
PHE A 321
 None
 1.17A 2azxA-3cb5A:
undetectable		 2azxA-3cb5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU A  81
ILE A 122
GLU A  74
ILE A 105
 None
 0.92A 2azxA-3cb5A:
undetectable		 2azxA-3cb5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 414
GLY A 295
GLN A 317
ILE A 415
PHE A 321
 None
 1.18A 2azxB-3cb5A:
undetectable		 2azxB-3cb5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 6 LEU A 385
VAL A 371
ILE A 330
ILE A 417
 None
 0.89A 2piwA-3cb5A:
undetectable		 2piwA-3cb5A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A  70
ASP A 150
LEU A  73
HIS A  58
 None
 1.32A 2qxsB-3cb5A:
undetectable		 2qxsB-3cb5A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 282
ILE A 412
LEU A 338
ILE A 254
GLY A 392
 None
 1.23A 2v0mA-3cb5A:
undetectable		 2v0mA-3cb5A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 7 GLN A  33
VAL A  40
LEU A  18
LYS A  75
 None
 0.95A 3g8iA-3cb5A:
undetectable		 3g8iA-3cb5A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 VAL A 371
VAL A 353
ILE A 415
GLY A 357
 None
 0.83A 3hjoA-3cb5A:
undetectable		 3hjoA-3cb5A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 8 VAL A 371
VAL A 353
ILE A 415
GLY A 357
 None
 0.84A 3hjoB-3cb5A:
undetectable		 3hjoB-3cb5A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 5 ASP A  27
THR A  30
LEU A  31
LYS A 171
 None
 1.44A 4a3pA-3cb5A:
undetectable		 4a3pA-3cb5A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 5 TYR A 407
LEU A 409
LEU A 348
ARG A 345
 None
 1.09A 4em2A-3cb5A:
0.1		 4em2A-3cb5A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		3 / 3 TYR A 261
ARG A 272
HIS A 275
 None
 1.24A 4fubA-3cb5A:
undetectable		 4fubA-3cb5A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 TRP A  60
SER A 367
ALA A 174
LEU A 173
ALA A 101
 None
 1.21A 4l6v1-3cb5A:
undetectable
4l6v6-3cb5A:
undetectable		 4l6v1-3cb5A:
19.71
4l6v6-3cb5A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 TRP A  60
SER A 367
ALA A 174
LEU A 173
ALA A 101
 None
 1.18A 4l6va-3cb5A:
undetectable
4l6vf-3cb5A:
undetectable		 4l6va-3cb5A:
19.71
4l6vf-3cb5A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 11 GLY A 259
PHE A 300
SER A 204
TYR A 437
ASP A 277
 None
 1.28A 4rtrA-3cb5A:
undetectable		 4rtrA-3cb5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB101_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ARG A  14
LEU A 173
TYR A  51
TRP A  60
LEU A 379
 None
 1.42A 4x3uA-3cb5A:
undetectable		 4x3uA-3cb5A:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		3 / 3 MET A 195
ASP A 413
PHE A 425
 None
 1.05A 4xeyA-3cb5A:
undetectable		 4xeyA-3cb5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		3 / 3 MET A 195
ASP A 413
PHE A 425
 None
 1.05A 4xeyB-3cb5A:
undetectable		 4xeyB-3cb5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		3 / 3 PHE A 321
ILE A 415
ASP A 326
 None
 0.73A 5cswB-3cb5A:
undetectable		 5cswB-3cb5A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5eeuD-3cb5A:
undetectable
5eeuE-3cb5A:
undetectable		 5eeuD-3cb5A:
9.95
5eeuE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eeuN-3cb5A:
undetectable
5eeuO-3cb5A:
undetectable		 5eeuN-3cb5A:
9.95
5eeuO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5eeuO-3cb5A:
undetectable
5eeuP-3cb5A:
undetectable		 5eeuO-3cb5A:
9.95
5eeuP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eeuP-3cb5A:
undetectable
5eeuQ-3cb5A:
undetectable		 5eeuP-3cb5A:
9.95
5eeuQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eeuS-3cb5A:
undetectable
5eeuT-3cb5A:
undetectable		 5eeuS-3cb5A:
9.95
5eeuT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eevA-3cb5A:
undetectable
5eevB-3cb5A:
undetectable		 5eevA-3cb5A:
9.95
5eevB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eevD-3cb5A:
undetectable
5eevE-3cb5A:
undetectable		 5eevD-3cb5A:
9.95
5eevE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eevN-3cb5A:
undetectable
5eevO-3cb5A:
undetectable		 5eevN-3cb5A:
9.95
5eevO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5eevO-3cb5A:
undetectable
5eevP-3cb5A:
undetectable		 5eevO-3cb5A:
9.95
5eevP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eevP-3cb5A:
undetectable
5eevQ-3cb5A:
undetectable		 5eevP-3cb5A:
9.95
5eevQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eevR-3cb5A:
undetectable
5eevS-3cb5A:
undetectable		 5eevR-3cb5A:
9.95
5eevS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eevS-3cb5A:
undetectable
5eevT-3cb5A:
undetectable		 5eevS-3cb5A:
9.95
5eevT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eewA-3cb5A:
undetectable
5eewB-3cb5A:
undetectable		 5eewA-3cb5A:
9.95
5eewB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5eewD-3cb5A:
undetectable
5eewE-3cb5A:
undetectable		 5eewD-3cb5A:
9.95
5eewE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.96A 5eewF-3cb5A:
undetectable
5eewG-3cb5A:
undetectable		 5eewF-3cb5A:
9.95
5eewG-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eewN-3cb5A:
undetectable
5eewO-3cb5A:
undetectable		 5eewN-3cb5A:
9.95
5eewO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5eewO-3cb5A:
undetectable
5eewP-3cb5A:
undetectable		 5eewO-3cb5A:
9.95
5eewP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eewP-3cb5A:
undetectable
5eewQ-3cb5A:
undetectable		 5eewP-3cb5A:
9.95
5eewQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eewQ-3cb5A:
undetectable
5eewR-3cb5A:
undetectable		 5eewQ-3cb5A:
9.95
5eewR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eewR-3cb5A:
undetectable
5eewS-3cb5A:
undetectable		 5eewR-3cb5A:
9.95
5eewS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eewS-3cb5A:
undetectable
5eewT-3cb5A:
undetectable		 5eewS-3cb5A:
9.95
5eewT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eexA-3cb5A:
undetectable
5eexB-3cb5A:
undetectable		 5eexA-3cb5A:
9.95
5eexB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5eexD-3cb5A:
undetectable
5eexE-3cb5A:
undetectable		 5eexD-3cb5A:
9.95
5eexE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.96A 5eexF-3cb5A:
undetectable
5eexG-3cb5A:
undetectable		 5eexF-3cb5A:
9.95
5eexG-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eexN-3cb5A:
undetectable
5eexO-3cb5A:
undetectable		 5eexN-3cb5A:
9.95
5eexO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5eexO-3cb5A:
undetectable
5eexP-3cb5A:
undetectable		 5eexO-3cb5A:
9.95
5eexP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eexP-3cb5A:
undetectable
5eexQ-3cb5A:
undetectable		 5eexP-3cb5A:
9.95
5eexQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eexQ-3cb5A:
undetectable
5eexR-3cb5A:
undetectable		 5eexQ-3cb5A:
9.95
5eexR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eexR-3cb5A:
undetectable
5eexS-3cb5A:
undetectable		 5eexR-3cb5A:
9.95
5eexS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eexS-3cb5A:
undetectable
5eexT-3cb5A:
undetectable		 5eexS-3cb5A:
9.95
5eexT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eeyA-3cb5A:
undetectable
5eeyB-3cb5A:
undetectable		 5eeyA-3cb5A:
9.95
5eeyB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5eeyD-3cb5A:
undetectable
5eeyE-3cb5A:
undetectable		 5eeyD-3cb5A:
9.95
5eeyE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.96A 5eeyF-3cb5A:
undetectable
5eeyG-3cb5A:
undetectable		 5eeyF-3cb5A:
9.95
5eeyG-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eeyN-3cb5A:
undetectable
5eeyO-3cb5A:
undetectable		 5eeyN-3cb5A:
9.95
5eeyO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5eeyO-3cb5A:
undetectable
5eeyP-3cb5A:
undetectable		 5eeyO-3cb5A:
9.95
5eeyP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eeyP-3cb5A:
undetectable
5eeyQ-3cb5A:
undetectable		 5eeyP-3cb5A:
9.95
5eeyQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eeyQ-3cb5A:
undetectable
5eeyR-3cb5A:
undetectable		 5eeyQ-3cb5A:
9.95
5eeyR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eeyR-3cb5A:
undetectable
5eeyS-3cb5A:
undetectable		 5eeyR-3cb5A:
9.95
5eeyS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eeyS-3cb5A:
undetectable
5eeyT-3cb5A:
undetectable		 5eeyS-3cb5A:
9.95
5eeyT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eezA-3cb5A:
undetectable
5eezB-3cb5A:
undetectable		 5eezA-3cb5A:
9.95
5eezB-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5eezD-3cb5A:
undetectable
5eezE-3cb5A:
undetectable		 5eezD-3cb5A:
9.95
5eezE-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5eezF-3cb5A:
undetectable
5eezG-3cb5A:
undetectable		 5eezF-3cb5A:
9.95
5eezG-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eezN-3cb5A:
undetectable
5eezO-3cb5A:
undetectable		 5eezN-3cb5A:
9.95
5eezO-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5eezO-3cb5A:
undetectable
5eezP-3cb5A:
undetectable		 5eezO-3cb5A:
9.95
5eezP-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5eezP-3cb5A:
undetectable
5eezQ-3cb5A:
undetectable		 5eezP-3cb5A:
9.95
5eezQ-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eezQ-3cb5A:
undetectable
5eezR-3cb5A:
undetectable		 5eezQ-3cb5A:
9.95
5eezR-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5eezR-3cb5A:
undetectable
5eezS-3cb5A:
undetectable		 5eezR-3cb5A:
9.95
5eezS-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5eezS-3cb5A:
undetectable
5eezT-3cb5A:
undetectable		 5eezS-3cb5A:
9.95
5eezT-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5eezT-3cb5A:
undetectable
5eezU-3cb5A:
undetectable		 5eezT-3cb5A:
9.95
5eezU-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef0A-3cb5A:
undetectable
5ef0B-3cb5A:
undetectable		 5ef0A-3cb5A:
9.95
5ef0B-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5ef0D-3cb5A:
undetectable
5ef0E-3cb5A:
undetectable		 5ef0D-3cb5A:
9.95
5ef0E-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef0F-3cb5A:
undetectable
5ef0G-3cb5A:
undetectable		 5ef0F-3cb5A:
9.95
5ef0G-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef0N-3cb5A:
undetectable
5ef0O-3cb5A:
undetectable		 5ef0N-3cb5A:
9.95
5ef0O-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5ef0O-3cb5A:
undetectable
5ef0P-3cb5A:
undetectable		 5ef0O-3cb5A:
9.95
5ef0P-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5ef0P-3cb5A:
undetectable
5ef0Q-3cb5A:
undetectable		 5ef0P-3cb5A:
9.95
5ef0Q-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef0Q-3cb5A:
undetectable
5ef0R-3cb5A:
undetectable		 5ef0Q-3cb5A:
9.95
5ef0R-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5ef0R-3cb5A:
undetectable
5ef0S-3cb5A:
undetectable		 5ef0R-3cb5A:
9.95
5ef0S-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef0S-3cb5A:
undetectable
5ef0T-3cb5A:
undetectable		 5ef0S-3cb5A:
9.95
5ef0T-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef1A-3cb5A:
undetectable
5ef1B-3cb5A:
undetectable		 5ef1A-3cb5A:
9.95
5ef1B-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef1D-3cb5A:
undetectable
5ef1E-3cb5A:
undetectable		 5ef1D-3cb5A:
9.95
5ef1E-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef1F-3cb5A:
undetectable
5ef1G-3cb5A:
undetectable		 5ef1F-3cb5A:
9.95
5ef1G-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5ef1N-3cb5A:
undetectable
5ef1O-3cb5A:
undetectable		 5ef1N-3cb5A:
9.95
5ef1O-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5ef1O-3cb5A:
undetectable
5ef1P-3cb5A:
undetectable		 5ef1O-3cb5A:
9.95
5ef1P-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5ef1P-3cb5A:
undetectable
5ef1Q-3cb5A:
undetectable		 5ef1P-3cb5A:
9.95
5ef1Q-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef1Q-3cb5A:
undetectable
5ef1R-3cb5A:
undetectable		 5ef1Q-3cb5A:
9.95
5ef1R-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5ef1R-3cb5A:
undetectable
5ef1S-3cb5A:
undetectable		 5ef1R-3cb5A:
9.95
5ef1S-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef1S-3cb5A:
undetectable
5ef1T-3cb5A:
undetectable		 5ef1S-3cb5A:
9.95
5ef1T-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.94A 5ef1T-3cb5A:
undetectable
5ef1U-3cb5A:
undetectable		 5ef1T-3cb5A:
9.95
5ef1U-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef2A-3cb5A:
undetectable
5ef2B-3cb5A:
undetectable		 5ef2A-3cb5A:
9.95
5ef2B-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5ef2D-3cb5A:
undetectable
5ef2E-3cb5A:
undetectable		 5ef2D-3cb5A:
9.95
5ef2E-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef2F-3cb5A:
undetectable
5ef2G-3cb5A:
undetectable		 5ef2F-3cb5A:
9.95
5ef2G-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef2N-3cb5A:
undetectable
5ef2O-3cb5A:
undetectable		 5ef2N-3cb5A:
9.95
5ef2O-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5ef2O-3cb5A:
undetectable
5ef2P-3cb5A:
undetectable		 5ef2O-3cb5A:
9.95
5ef2P-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef2P-3cb5A:
undetectable
5ef2Q-3cb5A:
undetectable		 5ef2P-3cb5A:
9.95
5ef2Q-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef2Q-3cb5A:
undetectable
5ef2R-3cb5A:
undetectable		 5ef2Q-3cb5A:
9.95
5ef2R-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5ef2R-3cb5A:
undetectable
5ef2S-3cb5A:
undetectable		 5ef2R-3cb5A:
9.95
5ef2S-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef2S-3cb5A:
undetectable
5ef2T-3cb5A:
undetectable		 5ef2S-3cb5A:
9.95
5ef2T-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.94A 5ef2T-3cb5A:
undetectable
5ef2U-3cb5A:
undetectable		 5ef2T-3cb5A:
9.95
5ef2U-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 GLY A 295
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef3A-3cb5A:
undetectable
5ef3B-3cb5A:
undetectable		 5ef3A-3cb5A:
9.95
5ef3B-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.94A 5ef3D-3cb5A:
undetectable
5ef3E-3cb5A:
undetectable		 5ef3D-3cb5A:
9.95
5ef3E-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 SER A 191
ALA A 187
THR A 426
THR A 414
ILE A 184
 None
 0.95A 5ef3F-3cb5A:
undetectable
5ef3G-3cb5A:
undetectable		 5ef3F-3cb5A:
9.95
5ef3G-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef3N-3cb5A:
undetectable
5ef3O-3cb5A:
undetectable		 5ef3N-3cb5A:
9.95
5ef3O-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.95A 5ef3O-3cb5A:
undetectable
5ef3P-3cb5A:
undetectable		 5ef3O-3cb5A:
9.95
5ef3P-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.96A 5ef3P-3cb5A:
undetectable
5ef3Q-3cb5A:
undetectable		 5ef3P-3cb5A:
9.95
5ef3Q-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef3Q-3cb5A:
undetectable
5ef3R-3cb5A:
undetectable		 5ef3Q-3cb5A:
9.95
5ef3R-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.98A 5ef3R-3cb5A:
undetectable
5ef3S-3cb5A:
undetectable		 5ef3R-3cb5A:
9.95
5ef3S-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		5 / 10 ALA A 187
THR A 426
THR A 414
ILE A 184
SER A 191
 None
 0.97A 5ef3S-3cb5A:
undetectable
5ef3T-3cb5A:
undetectable		 5ef3S-3cb5A:
9.95
5ef3T-3cb5A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 6 GLU A 363
ALA A 170
LEU A 173
SER A 368
 None
 1.12A 5phhA-3cb5A:
undetectable		 5phhA-3cb5A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3cb5 FACT COMPLEX SUBUNIT
SPT16
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG A 354
ALA A 373
ILE A 337
LEU A 356
 None
 1.02A 5te8A-3cb5A:
undetectable		 5te8A-3cb5A:
24.53