SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 THR A  40
PRO A  43
THR A  42
 None
 0.95A 1dscC-3cbuA:
undetectable		 1dscC-3cbuA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 LEU A 176
LEU A 179
ALA A 138
PHE A 134
THR A 187
 None
 1.26A 3gwuA-3cbuA:
undetectable		 3gwuA-3cbuA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A  97
LEU A 100
THR A 101
TYR A 130
 None
 0.67A 3jusA-3cbuA:
undetectable		 3jusA-3cbuA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A  97
LEU A 100
THR A 101
TYR A 130
 None
 0.67A 3jusA-3cbuA:
undetectable		 3jusA-3cbuA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A  97
LEU A 100
THR A 101
TYR A 130
 None
 0.73A 3jusB-3cbuA:
undetectable		 3jusB-3cbuA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 7 ASP A  38
ILE A  51
GLY A  55
THR A  40
 None
 1.00A 4zxiA-3cbuA:
undetectable		 4zxiA-3cbuA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3cbu PROBABLE GST-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A 106
GLU A  99
THR A 167
ASN A  11
 None
 1.24A 6c71B-3cbuA:
undetectable		 6c71B-3cbuA:
15.81