SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cc8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		4 / 8 GLU A  60
ASP A  80
ILE A  81
LEU A 105
 None
 0.91A 1hmyA-3cc8A:
6.9		 1hmyA-3cc8A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		3 / 3 ALA A 139
VAL A 137
TRP A 146
 None
 0.88A 1micA-3cc8A:
undetectable
1micB-3cc8A:
undetectable		 1micA-3cc8A:
9.38
1micB-3cc8A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 LEU A  25
THR A  54
VAL A  56
ASP A  37
VAL A  35
 None
 1.41A 1o76A-3cc8A:
undetectable		 1o76A-3cc8A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 HIS A  27
ILE A  28
LEU A  45
ILE A 129
SER A 179
 None
 1.16A 1zq9A-3cc8A:
9.5		 1zq9A-3cc8A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C7V_B_MTXB1272_1
(PTERIDINE REDUCTASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 PHE A 171
TYR A 176
LEU A 105
PRO A 108
GLU A 103
 None
None
None
None
NI  A 231 (-3.1A)
 1.21A 2c7vB-3cc8A:
5.9		 2c7vB-3cc8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C7V_C_MTXC1272_1
(PTERIDINE REDUCTASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 PHE A 171
TYR A 176
LEU A 105
PRO A 108
GLU A 103
 None
None
None
None
NI  A 231 (-3.1A)
 1.12A 2c7vC-3cc8A:
5.4		 2c7vC-3cc8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 LEU A 105
ILE A  38
LEU A  36
ILE A 119
PHE A  98
 None
 1.06A 2ygqA-3cc8A:
undetectable		 2ygqA-3cc8A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  39
ALA A  44
LEU A  45
ALA A  61
VAL A 101
 None
 0.90A 2yvlB-3cc8A:
12.2		 2yvlB-3cc8A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_A_P77A203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 ASP A 100
SER A 128
PHE A 218
LEU A 154
ASP A 155
 None
None
None
None
NI  A 231 (-4.2A)
 1.43A 3m0wA-3cc8A:
undetectable
3m0wB-3cc8A:
undetectable
3m0wI-3cc8A:
undetectable
3m0wJ-3cc8A:
undetectable		 3m0wA-3cc8A:
19.02
3m0wB-3cc8A:
19.02
3m0wI-3cc8A:
19.02
3m0wJ-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 ASP A 100
SER A 128
PHE A 218
LEU A 154
ASP A 155
 None
None
None
None
NI  A 231 (-4.2A)
 1.48A 3m0wC-3cc8A:
undetectable
3m0wD-3cc8A:
undetectable
3m0wE-3cc8A:
undetectable
3m0wF-3cc8A:
undetectable		 3m0wC-3cc8A:
19.02
3m0wD-3cc8A:
19.02
3m0wE-3cc8A:
19.02
3m0wF-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_D_P77D203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 LEU A 154
ASP A 155
PHE A 218
ASP A 100
SER A 128
 None
NI  A 231 (-4.2A)
None
None
None
 1.45A 3m0wA-3cc8A:
undetectable
3m0wB-3cc8A:
undetectable
3m0wC-3cc8A:
undetectable
3m0wD-3cc8A:
undetectable		 3m0wA-3cc8A:
19.02
3m0wB-3cc8A:
19.02
3m0wC-3cc8A:
19.02
3m0wD-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 8 ASP A 100
SER A 128
PHE A 218
LEU A 154
ASP A 155
 None
None
None
None
NI  A 231 (-4.2A)
 1.46A 3m0wE-3cc8A:
undetectable
3m0wF-3cc8A:
undetectable
3m0wG-3cc8A:
undetectable
3m0wH-3cc8A:
undetectable		 3m0wE-3cc8A:
19.02
3m0wF-3cc8A:
19.02
3m0wG-3cc8A:
19.02
3m0wH-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 9 LEU A 154
ASP A 155
PHE A 218
ASP A 100
SER A 128
 None
NI  A 231 (-4.2A)
None
None
None
 1.45A 3m0wC-3cc8A:
undetectable
3m0wD-3cc8A:
undetectable
3m0wE-3cc8A:
undetectable
3m0wF-3cc8A:
undetectable		 3m0wC-3cc8A:
19.02
3m0wD-3cc8A:
19.02
3m0wE-3cc8A:
19.02
3m0wF-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 LEU A 154
ASP A 155
PHE A 218
ASP A 100
SER A 128
 None
NI  A 231 (-4.2A)
None
None
None
 1.43A 3m0wE-3cc8A:
undetectable
3m0wF-3cc8A:
undetectable
3m0wG-3cc8A:
undetectable
3m0wH-3cc8A:
undetectable		 3m0wE-3cc8A:
19.02
3m0wF-3cc8A:
19.02
3m0wG-3cc8A:
19.02
3m0wH-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 LEU A 154
ASP A 155
ASP A 100
SER A 128
PHE A 218
 None
NI  A 231 (-4.2A)
None
None
None
 1.46A 3m0wA-3cc8A:
undetectable
3m0wB-3cc8A:
undetectable
3m0wI-3cc8A:
undetectable
3m0wJ-3cc8A:
undetectable		 3m0wA-3cc8A:
19.02
3m0wB-3cc8A:
19.02
3m0wI-3cc8A:
19.02
3m0wJ-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 LEU A 105
VAL A 101
PHE A  98
VAL A 111
PHE A 162
 None
 1.33A 3u9fB-3cc8A:
undetectable
3u9fC-3cc8A:
undetectable		 3u9fB-3cc8A:
19.17
3u9fC-3cc8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 11 LEU A 105
VAL A 101
PHE A  98
VAL A 111
PHE A 162
 None
 1.29A 3u9fN-3cc8A:
undetectable
3u9fO-3cc8A:
undetectable		 3u9fN-3cc8A:
19.17
3u9fO-3cc8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 PHE A 162
LEU A 105
VAL A 101
PHE A  98
VAL A 111
 None
 1.38A 3u9fP-3cc8A:
undetectable
3u9fS-3cc8A:
undetectable		 3u9fP-3cc8A:
19.17
3u9fS-3cc8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  39
ILE A  81
ASP A 100
HIS A 104
LEU A 105
 None
None
None
NI  A 231 (-3.2A)
None
 0.86A 3uj6A-3cc8A:
14.5		 3uj6A-3cc8A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  99
ASN A  21
GLU A  60
VAL A 101
HIS A 104
 None
None
None
None
NI  A 231 (-3.2A)
 1.23A 4azsA-3cc8A:
10.9		 4azsA-3cc8A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 8 GLY A  43
GLY A  58
TYR A  88
LEU A  36
VAL A  35
 None
 1.39A 4fgzA-3cc8A:
14.5		 4fgzA-3cc8A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		4 / 6 TYR A 185
GLU A 214
TYR A 220
PHE A 164
 None
 1.47A 4twdG-3cc8A:
undetectable
4twdH-3cc8A:
undetectable		 4twdG-3cc8A:
20.95
4twdH-3cc8A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		4 / 7 ASN A 165
LEU A 168
ARG A 169
LEU A 172
 None
 0.71A 4wg0B-3cc8A:
undetectable
4wg0C-3cc8A:
undetectable		 4wg0B-3cc8A:
7.07
4wg0C-3cc8A:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		4 / 7 GLU A 223
ILE A  28
LEU A  73
ILE A  97
 None
 0.99A 4xumA-3cc8A:
undetectable		 4xumA-3cc8A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 VAL A 111
PHE A  98
LEU A  73
VAL A  56
GLY A  99
 None
 1.45A 6brdA-3cc8A:
3.0		 6brdA-3cc8A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3cc8 PUTATIVE
METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 LEU A  25
ILE A 221
ILE A  49
VAL A  35
ILE A  28
 None
 0.94A 6emuA-3cc8A:
undetectable		 6emuA-3cc8A:
26.86