SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ccf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 10 LEU A 227
GLU A 232
ALA A 147
LEU A 152
ALA A 212
 None
 1.23A 1ie4A-3ccfA:
undetectable
1ie4C-3ccfA:
undetectable		 1ie4A-3ccfA:
17.99
1ie4C-3ccfA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		3 / 3 GLY A  46
ASP A  67
ASN A 105
 None
 0.38A 1vq1A-3ccfA:
12.0		 1vq1A-3ccfA:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 10 TYR A  80
GLY A  48
THR A  49
ALA A  76
VAL A  63
 None
 1.34A 2coiA-3ccfA:
undetectable
2coiB-3ccfA:
undetectable		 2coiA-3ccfA:
21.18
2coiB-3ccfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 10 VAL A  63
TYR A  80
GLY A  48
THR A  49
ALA A  76
 None
 1.33A 2coiA-3ccfA:
undetectable
2coiB-3ccfA:
undetectable		 2coiA-3ccfA:
21.18
2coiB-3ccfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 TYR A  80
GLY A  48
THR A  49
ALA A  76
VAL A  63
 None
 1.30A 2cojA-3ccfA:
undetectable
2cojB-3ccfA:
undetectable		 2cojA-3ccfA:
21.18
2cojB-3ccfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 5 ILE A 118
PRO A 114
PHE A 135
ILE A 254
 None
 1.11A 2hjhA-3ccfA:
4.8		 2hjhA-3ccfA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ASP A  44
GLY A  46
GLY A  48
LEU A  52
ASN A 105
 None
 0.91A 2nxeA-3ccfA:
17.6		 2nxeA-3ccfA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ASP A  44
LEU A  45
GLY A  46
GLY A  48
ASN A 105
 None
 0.58A 2nxeA-3ccfA:
17.6		 2nxeA-3ccfA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ASP A  44
LEU A  45
GLY A  46
GLY A  48
ASN A 105
 None
 0.55A 2nxeB-3ccfA:
17.6		 2nxeB-3ccfA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 6 THR A  49
ASP A  67
ASN A  68
ASP A  89
 None
 0.63A 2okcA-3ccfA:
12.3		 2okcA-3ccfA:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		8 / 8 HIS A 109
GLY A 136
ASN A 140
TRP A 166
TRP A 207
PHE A 211
TYR A 249
ARG A 251
 BEZ  A 261 (-3.7A)
BEZ  A 261 ( 3.7A)
BEZ  A 261 (-3.1A)
BEZ  A 261 (-3.7A)
BEZ  A 261 ( 4.6A)
BEZ  A 261 (-3.6A)
BEZ  A 261 (-4.2A)
BEZ  A 261 (-3.9A)
 0.00A 3ccfA-3ccfA:
41.2		 3ccfA-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 8 HIS A 109
GLY A 136
TRP A 110
PHE A 211
TYR A 249
ARG A 251
 BEZ  A 261 (-3.7A)
BEZ  A 261 ( 3.7A)
None
BEZ  A 261 (-3.6A)
BEZ  A 261 (-4.2A)
BEZ  A 261 (-3.9A)
 1.47A 3ccfA-3ccfA:
41.2		 3ccfA-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		8 / 8 HIS A 109
ASN A 140
ILE A 141
TRP A 166
TRP A 207
PHE A 211
TYR A 249
ARG A 251
 BEZ  A 261 (-3.7A)
BEZ  A 261 (-3.1A)
None
BEZ  A 261 (-3.7A)
BEZ  A 261 ( 4.6A)
BEZ  A 261 (-3.6A)
BEZ  A 261 (-4.2A)
BEZ  A 261 (-3.9A)
 0.67A 3ccfB-3ccfA:
35.6		 3ccfB-3ccfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 8 ILE A 144
TRP A 166
TRP A 207
PHE A 211
 None
BEZ  A 261 (-3.7A)
BEZ  A 261 ( 4.6A)
BEZ  A 261 (-3.6A)
 1.21A 3ccfB-3ccfA:
35.6		 3ccfB-3ccfA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ASP A  44
LEU A  45
GLY A  46
LEU A  52
ASP A  67
 None
 0.69A 3cjtC-3ccfA:
17.9		 3cjtC-3ccfA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 12 LEU A  45
GLY A  46
GLY A  48
LEU A  52
ASN A 105
LEU A 108
 None
 1.13A 3cjtO-3ccfA:
17.9		 3cjtO-3ccfA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.63A 3g88A-3ccfA:
14.3		 3g88A-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.61A 3g88B-3ccfA:
14.3		 3g88B-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.59A 3g89A-3ccfA:
14.2		 3g89A-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.57A 3g89B-3ccfA:
14.2		 3g89B-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.62A 3g8bA-3ccfA:
14.2		 3g8bA-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
ALA A  90
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.58A 3g8bB-3ccfA:
12.9		 3g8bB-3ccfA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		3 / 3 GLY A  48
ASP A  67
ASP A  89
 None
 0.44A 3ou7C-3ccfA:
16.6		 3ou7C-3ccfA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ALA A 214
PHE A 215
TYR A 249
ILE A 141
LEU A 145
 None
None
BEZ  A 261 (-4.2A)
None
None
 0.99A 3rukA-3ccfA:
undetectable		 3rukA-3ccfA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 6 GLU A  28
GLY A  27
LEU A  52
GLU A 134
 None
 0.99A 3w9tB-3ccfA:
undetectable		 3w9tB-3ccfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 6 GLU A  28
GLY A  27
LEU A  52
GLU A 134
 None
 0.98A 3w9tE-3ccfA:
undetectable		 3w9tE-3ccfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 6 GLU A  28
GLY A  27
LEU A  52
GLU A 134
 None
 0.98A 3w9tF-3ccfA:
undetectable		 3w9tF-3ccfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 11 ASP A  44
GLY A  46
GLY A  48
ASP A  67
ASN A 105
 None
 0.68A 4dcmA-3ccfA:
14.6		 4dcmA-3ccfA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
MET A  72
ASP A  89
 None
 0.58A 4iv8A-3ccfA:
18.5		 4iv8A-3ccfA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASP A  67
MET A  72
ASP A  89
 None
 0.60A 4iv8B-3ccfA:
18.5		 4iv8B-3ccfA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ALA A  69
ALA A  90
MET A 107
 None
 0.66A 4kicA-3ccfA:
16.5		 4kicA-3ccfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ALA A  69
ALA A  90
MET A 107
 None
 0.72A 4kicB-3ccfA:
15.6		 4kicB-3ccfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 6 ARG A  91
ALA A 117
ASP A  89
LEU A 108
 None
 1.06A 4ot2A-3ccfA:
undetectable		 4ot2A-3ccfA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ILE A 171
GLY A 172
PRO A 169
VAL A 175
ILE A 254
 None
 1.02A 4rvdA-3ccfA:
16.1		 4rvdA-3ccfA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 ILE A 171
GLY A 172
PRO A 169
VAL A 175
ILE A 254
 None
 1.05A 4rvgA-3ccfA:
16.2		 4rvgA-3ccfA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 7 ALA A 124
ASP A  89
ARG A  91
GLU A 113
 None
 0.78A 5bs8A-3ccfA:
undetectable
5bs8C-3ccfA:
undetectable
5bs8D-3ccfA:
undetectable		 5bs8A-3ccfA:
20.55
5bs8C-3ccfA:
20.55
5bs8D-3ccfA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 7 ALA A 124
ASP A  89
ARG A  91
GLU A 113
 None
 0.78A 5btdA-3ccfA:
undetectable
5btdB-3ccfA:
undetectable
5btdC-3ccfA:
undetectable		 5btdA-3ccfA:
20.55
5btdB-3ccfA:
22.64
5btdC-3ccfA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 7 ALA A 124
ASP A  89
ARG A  91
GLU A 113
 None
 0.76A 5btdA-3ccfA:
undetectable
5btdC-3ccfA:
undetectable
5btdD-3ccfA:
undetectable		 5btdA-3ccfA:
20.55
5btdC-3ccfA:
20.55
5btdD-3ccfA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		4 / 4 ASN A 105
ILE A 171
TYR A 187
PHE A 183
 None
 1.37A 5igvA-3ccfA:
undetectable		 5igvA-3ccfA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 GLY A  46
GLY A  48
ASN A  68
ASP A  89
ALA A 106
 None
None
None
None
BEZ  A 261 ( 4.7A)
 0.73A 5kpcB-3ccfA:
14.5		 5kpcB-3ccfA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 12 PHE A 215
LEU A 148
ALA A 212
PRO A 165
PHE A 211
ILE A 141
 None
None
None
None
BEZ  A 261 (-3.6A)
None
 1.46A 5ljeA-3ccfA:
undetectable		 5ljeA-3ccfA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		5 / 12 LEU A 235
ILE A 144
ILE A 208
MET A 204
HIS A 109
 None
None
None
None
BEZ  A 261 (-3.7A)
 1.21A 5y2tB-3ccfA:
undetectable		 5y2tB-3ccfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 12 ASP A  44
GLY A  46
GLY A  48
ALA A  69
ASP A  89
PHE A 103
 None
 0.96A 6nj9K-3ccfA:
9.7		 6nj9K-3ccfA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE
(Trichormus
variabilis) 		6 / 12 ASP A  44
GLY A  46
GLY A  48
GLN A  51
ALA A  69
ASP A  89
 None
 0.79A 6nj9K-3ccfA:
9.7		 6nj9K-3ccfA:
20.28