SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ccq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		5 / 12 LEU C 156
VAL C 153
LEU C 207
ALA C 210
PHE C 194
 None
 1.05A 1gseB-3ccqC:
undetectable		 1gseB-3ccqC:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		4 / 7 SER C 197
ASP C 198
GLU C 242
GLU C 245
 None
 1.19A 1knyA-3ccqC:
undetectable
1knyB-3ccqC:
undetectable		 1knyA-3ccqC:
21.82
1knyB-3ccqC:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		4 / 8 SER C 197
ASP C 198
GLU C 242
GLU C 245
 None
 1.08A 1knyA-3ccqC:
undetectable
1knyB-3ccqC:
undetectable		 1knyA-3ccqC:
21.82
1knyB-3ccqC:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		4 / 7 GLY C 227
ALA C 224
ASP C 222
ARG C 231
 None
None
G  0 672 ( 2.9A)
None
 0.81A 3ur0B-3ccqC:
undetectable		 3ur0B-3ccqC:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		5 / 11 SER C 238
LEU C 240
THR C 236
GLU C  15
ALA C   3
 None
 1.13A 4e0fA-3ccqC:
undetectable		 4e0fA-3ccqC:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		5 / 12 ASP C  29
ILE C  31
ARG C  27
GLU C 221
GLY C  32
 None
None
G  0 657 ( 3.3A)
None
None
 1.29A 5il1A-3ccqC:
undetectable		 5il1A-3ccqC:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		5 / 12 ASP C  29
ILE C  31
ARG C  27
GLU C 221
GLY C  32
 None
None
G  0 657 ( 3.3A)
None
None
 1.27A 5k7uA-3ccqC:
undetectable		 5k7uA-3ccqC:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		4 / 7 VAL C 139
VAL C  16
PRO C  19
ALA C   3
 None
 0.71A 5ospA-3ccqC:
undetectable		 5ospA-3ccqC:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3ccq 50S RIBOSOMAL
PROTEIN L4P
(Haloarcula
marismortui) 		4 / 8 ILE C  31
ASN C 219
PRO C 137
THR C 118
 None
G  0 672 ( 3.6A)
None
None
 0.90A 5x23A-3ccqC:
undetectable		 5x23A-3ccqC:
19.25