SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		4 / 8 LEU A 312
TYR A 283
MET A 316
VAL A 336
 None
 0.98A 1fduB-3cddA:
undetectable		 1fduB-3cddA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		3 / 3 ARG A  94
THR A 152
VAL A 101
 None
 0.89A 1hxbA-3cddA:
undetectable		 1hxbA-3cddA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		5 / 10 VAL A  70
ILE A  65
GLY A  66
GLY A  67
THR A  72
 None
 0.97A 1k6cA-3cddA:
undetectable		 1k6cA-3cddA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		3 / 3 TRP A  78
VAL A  79
PRO A  80
 None
 0.52A 1rg1A-3cddA:
undetectable		 1rg1A-3cddA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		3 / 3 TRP A  78
VAL A  79
PRO A  80
 None
 0.52A 1rh0A-3cddA:
undetectable		 1rh0A-3cddA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		5 / 11 TYR A 283
MET A 280
GLY A 201
ALA A 199
VAL A 305
 None
 1.45A 2cojA-3cddA:
undetectable
2cojB-3cddA:
undetectable		 2cojA-3cddA:
19.76
2cojB-3cddA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		3 / 3 ARG A  94
THR A 152
VAL A 101
 None
 0.85A 2q64A-3cddA:
undetectable		 2q64A-3cddA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		3 / 3 ARG A  94
THR A 152
VAL A 101
 None
 0.87A 2qakA-3cddA:
undetectable		 2qakA-3cddA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		5 / 12 PHE A 142
ILE A 178
ILE A 147
GLU A 151
VAL A 166
 None
 1.16A 4a97B-3cddA:
undetectable
4a97C-3cddA:
undetectable		 4a97B-3cddA:
22.08
4a97C-3cddA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN
(Shewanella
oneidensis) 		5 / 12 LEU A 100
LEU A 168
HIS A 154
ILE A 178
ALA A 161
 None
 1.42A 5xprA-3cddA:
undetectable		 5xprA-3cddA:
20.38