SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 7 ARG A 116
ASP A 531
ASP A 515
ARG A 422
 None
 1.48A 1ceaB-3cdiA:
undetectable		 1ceaB-3cdiA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 5 THR A 378
THR A 376
GLU A 453
HIS A 402
 None
 1.37A 1d4fB-3cdiA:
undetectable		 1d4fB-3cdiA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 LEU A 501
LEU A 511
GLY A 512
ALA A 545
PHE A 516
 None
 1.09A 1gs4A-3cdiA:
undetectable		 1gs4A-3cdiA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 11 GLY A 425
SER A 462
ASP A 531
GLN A 529
ILE A 122
 None
 1.24A 1jzsA-3cdiA:
3.5		 1jzsA-3cdiA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 8 TYR A 403
GLU A 423
SER A 409
TYR A 408
 None
 1.21A 1nx9B-3cdiA:
undetectable		 1nx9B-3cdiA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 ALA A 322
LEU A 304
LEU A 316
ASN A 262
ARG A 268
 None
 1.30A 2ceoB-3cdiA:
undetectable		 2ceoB-3cdiA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 GLY A 156
ALA A 157
VAL A  84
VAL A 140
ILE A 118
 None
 1.04A 2f8gA-3cdiA:
undetectable		 2f8gA-3cdiA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 ALA A 464
VAL A 410
HIS A 426
PHE A 405
SER A 452
 None
 1.45A 2gl0A-3cdiA:
1.7
2gl0C-3cdiA:
1.6		 2gl0A-3cdiA:
13.85
2gl0C-3cdiA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 HIS A 426
PHE A 405
SER A 452
ALA A 464
VAL A 410
 None
 1.43A 2gl0D-3cdiA:
1.6
2gl0E-3cdiA:
undetectable		 2gl0D-3cdiA:
13.85
2gl0E-3cdiA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 GLU A 213
LEU A 435
GLY A 427
VAL A 466
ALA A 469
 None
 1.25A 2kceA-3cdiA:
undetectable		 2kceA-3cdiA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 7 VAL A  56
ILE A 155
ALA A 159
VAL A  54
 None
 0.64A 2xrzB-3cdiA:
undetectable		 2xrzB-3cdiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 THR A 376
VAL A 478
GLY A 380
THR A 381
 None
 0.96A 3cflA-3cdiA:
undetectable		 3cflA-3cdiA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 GLY A 178
ALA A 227
MET A 224
LEU A 193
GLU A 195
 None
 1.16A 3ckkA-3cdiA:
undetectable		 3ckkA-3cdiA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 ILE A 556
SER A 465
GLY A 486
SER A 460
LEU A 350
 None
 1.12A 3ik6B-3cdiA:
undetectable
3ik6E-3cdiA:
undetectable		 3ik6B-3cdiA:
16.67
3ik6E-3cdiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 SER A 460
LEU A 350
ILE A 556
SER A 465
GLY A 486
 None
 1.09A 3ik6B-3cdiA:
undetectable
3ik6E-3cdiA:
undetectable		 3ik6B-3cdiA:
16.67
3ik6E-3cdiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 SER A 460
LEU A 350
ILE A 556
SER A 465
GLY A 486
 None
 1.13A 3iluB-3cdiA:
undetectable
3iluE-3cdiA:
undetectable		 3iluB-3cdiA:
16.67
3iluE-3cdiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		6 / 12 VAL A 212
ILE A 556
GLY A 551
ALA A 519
ALA A 485
CYH A 467
 None
 1.23A 3sufD-3cdiA:
undetectable		 3sufD-3cdiA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 11 GLY A 459
SER A 457
PHE A 405
GLY A 427
ASN A 404
 None
 1.11A 3v3nA-3cdiA:
undetectable		 3v3nA-3cdiA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 11 GLY A 459
SER A 457
PHE A 405
GLY A 427
ASN A 404
 None
 1.11A 3v3nD-3cdiA:
undetectable		 3v3nD-3cdiA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		3 / 3 ARG A 106
GLU A  88
THR A  90
 None
 0.69A 3v4tA-3cdiA:
undetectable		 3v4tA-3cdiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 7 LEU A 117
ALA A 153
VAL A 143
ILE A 114
 None
 0.89A 3wsjB-3cdiA:
undetectable		 3wsjB-3cdiA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 VAL A  39
VAL A 238
ASN A 187
ILE A 151
 None
 1.43A 4cutA-3cdiA:
1.4		 4cutA-3cdiA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 6 ALA A 159
GLY A 250
LEU A 245
VAL A 246
 None
 0.97A 4dubA-3cdiA:
3.8		 4dubA-3cdiA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 5 VAL A 269
ARG A 268
GLU A 307
LEU A 311
 None
 1.31A 4hojA-3cdiA:
undetectable		 4hojA-3cdiA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		3 / 3 GLU A  88
ILE A 151
ALA A 138
 None
 0.47A 4wnwB-3cdiA:
2.2		 4wnwB-3cdiA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 5 ARG A 432
GLY A 433
GLU A 215
SER A 452
 None
 1.25A 4z3oA-3cdiA:
undetectable
4z3oB-3cdiA:
undetectable		 4z3oA-3cdiA:
24.70
4z3oB-3cdiA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 PRO A 171
PHE A 130
ILE A 166
PHE A 126
ASN A 169
 None
 1.36A 5hgcA-3cdiA:
undetectable		 5hgcA-3cdiA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 7 GLY A 520
GLY A 486
LEU A 429
GLU A 221
 None
 0.85A 5izfA-3cdiA:
undetectable		 5izfA-3cdiA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 VAL A 238
VAL A 237
TYR A  34
GLN A  33
 None
 1.30A 5qggA-3cdiA:
undetectable		 5qggA-3cdiA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 VAL A 238
VAL A 237
TYR A  34
GLN A  33
 None
 1.29A 5qgoA-3cdiA:
undetectable		 5qgoA-3cdiA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 VAL A 238
VAL A 237
TYR A  34
GLN A  33
 None
 1.32A 5qgpA-3cdiA:
undetectable		 5qgpA-3cdiA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 VAL A 238
VAL A 237
TYR A  34
GLN A  33
 None
 1.33A 5qgqA-3cdiA:
undetectable		 5qgqA-3cdiA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 4 VAL A 238
VAL A 237
TYR A  34
GLN A  33
 None
 1.30A 5qhbA-3cdiA:
undetectable		 5qhbA-3cdiA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 12 VAL A 352
ALA A 563
GLY A 558
HIS A 555
ALA A 483
 None
 0.84A 5xv7A-3cdiA:
undetectable		 5xv7A-3cdiA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 8 PHE A 366
LEU A 365
LEU A 471
ALA A 472
 None
 0.87A 5y7pE-3cdiA:
undetectable		 5y7pE-3cdiA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 SER A 460
LEU A 350
ILE A 556
SER A 465
GLY A 486
 None
 1.24A 6dlzA-3cdiA:
undetectable
6dlzD-3cdiA:
undetectable		 6dlzA-3cdiA:
10.86
6dlzD-3cdiA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 ILE A 556
SER A 465
GLY A 486
SER A 460
LEU A 350
 None
 1.25A 6dlzB-3cdiA:
undetectable
6dlzC-3cdiA:
undetectable		 6dlzB-3cdiA:
10.86
6dlzC-3cdiA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 SER A 460
LEU A 350
ILE A 556
SER A 465
GLY A 486
 None
 1.25A 6dm1A-3cdiA:
undetectable
6dm1D-3cdiA:
undetectable		 6dm1A-3cdiA:
10.86
6dm1D-3cdiA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		5 / 10 ILE A 556
SER A 465
GLY A 486
SER A 460
LEU A 350
 None
 1.25A 6dm1B-3cdiA:
undetectable
6dm1C-3cdiA:
undetectable		 6dm1B-3cdiA:
10.86
6dm1C-3cdiA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3cdi POLYNUCLEOTIDE
PHOSPHORYLASE
(Escherichia
coli) 		4 / 6 ILE A 424
ALA A 115
ARG A 116
ASP A 531
 None
 1.07A 6hu9m-3cdiA:
undetectable
6hu9q-3cdiA:
1.7		 6hu9m-3cdiA:
22.63
6hu9q-3cdiA:
12.38