SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		5 / 9 LEU B  44
ILE B  67
GLY B  70
ILE B  26
ILE B  53
 None
 1.06A 2avoA-3cdkB:
undetectable		 2avoA-3cdkB:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 5 PRO A 208
PRO A 178
ILE A 179
TYR A 211
 None
 0.98A 2jkjD-3cdkA:
undetectable		 2jkjD-3cdkA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 5 PRO A 208
PRO A 178
ILE A 179
TYR A 211
 None
 0.98A 2jkjF-3cdkA:
undetectable		 2jkjF-3cdkA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		5 / 9 GLY B 164
THR B 163
ALA B 114
LEU B 171
LEU B 160
 None
 1.29A 2npnA-3cdkB:
undetectable		 2npnA-3cdkB:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		5 / 9 ALA A 189
VAL A 215
GLY A 218
LEU A 167
ALA A 161
 None
 0.99A 2z0yA-3cdkA:
undetectable		 2z0yA-3cdkA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 6 PHE A 176
GLY A  26
ALA A 180
PRO A 178
 None
 0.93A 3bgdA-3cdkA:
undetectable		 3bgdA-3cdkA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 6 ASP A 162
LEU A 167
LEU A   7
HIS A 214
 None
 1.25A 3bj8C-3cdkA:
undetectable
3bj8D-3cdkA:
undetectable		 3bj8C-3cdkA:
20.16
3bj8D-3cdkA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		5 / 12 GLU B 109
GLY B 111
PHE B 178
ASP B 112
VAL B 107
 None
 1.14A 3nvkF-3cdkB:
undetectable
3nvkJ-3cdkB:
2.6		 3nvkF-3cdkB:
18.75
3nvkJ-3cdkB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		3 / 3 ASN B  68
ALA B  69
LYS B  71
 None
 0.99A 3runA-3cdkB:
undetectable		 3runA-3cdkB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 7 VAL A  51
LEU A  63
LEU A  66
ILE A 155
 None
 0.97A 3u5kB-3cdkA:
undetectable		 3u5kB-3cdkA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 8 VAL A  51
LEU A  63
LEU A  66
ILE A 155
 None
 0.90A 3u5kC-3cdkA:
undetectable		 3u5kC-3cdkA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		5 / 10 ILE A 149
SER A  78
ASN A  54
ILE A 109
ALA A 183
 None
 1.29A 3u6tA-3cdkA:
undetectable		 3u6tA-3cdkA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 5 VAL A  51
LEU A  63
LEU A  66
ILE A 155
 None
 0.90A 4a9jA-3cdkA:
undetectable		 4a9jA-3cdkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 5 VAL A  51
LEU A  63
LEU A  66
ILE A 155
 None
 0.91A 4a9jB-3cdkA:
undetectable		 4a9jB-3cdkA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis;
Bacillus
subtilis) 		5 / 12 PHE A  28
GLY B  25
ASN B  23
GLN B  45
ILE B  26
 None
 1.34A 4djfA-3cdkA:
undetectable		 4djfA-3cdkA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		4 / 8 ASN B  68
PRO B  55
TYR B  82
LEU B  66
 None
 0.97A 4jjkA-3cdkB:
undetectable		 4jjkA-3cdkB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		4 / 8 GLY B 103
THR B 163
LEU B 132
ASN B 115
 None
 1.00A 4m5mA-3cdkB:
undetectable		 4m5mA-3cdkB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		4 / 7 ALA B 100
GLY B 128
ALA B 129
THR B 163
 None
 0.71A 4r1zB-3cdkB:
undetectable		 4r1zB-3cdkB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		5 / 12 ALA A  14
ALA A  25
ILE A 155
ILE A  72
LEU A  49
 None
 1.01A 4r3aA-3cdkA:
undetectable		 4r3aA-3cdkA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		5 / 11 GLN B  45
GLY B 128
GLY B 127
ASN A  54
ILE B  26
 None
 1.45A 4zvmA-3cdkB:
2.5
4zvmB-3cdkB:
2.6		 4zvmA-3cdkB:
24.80
4zvmB-3cdkB:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		3 / 3 ASN B 134
ASP B 112
GLY B 111
 None
 0.31A 5fctB-3cdkB:
undetectable		 5fctB-3cdkB:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		5 / 12 ILE A 186
GLY A 184
HIS A 214
SER A  40
ILE A  41
 None
 1.12A 5igyA-3cdkA:
undetectable		 5igyA-3cdkA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Bacillus
subtilis) 		4 / 8 VAL B 107
ASP B 112
GLN B 110
GLY B 183
 None
 0.93A 5w3jB-3cdkB:
undetectable		 5w3jB-3cdkB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Bacillus
subtilis) 		4 / 8 VAL A  51
LEU A  63
LEU A  66
ILE A 155
 None
 0.92A 5y1yA-3cdkA:
undetectable		 5y1yA-3cdkA:
17.01