SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D06_A_ESTA304_1 (SULFOTRANSFERASE 1A1)	3cdl	TRANSCRIPTIONAL REGULATOR AEFR (Pseudomonas syringae group genomosp. 3)	5 / 10	LYS A 90 LYS A 128 HIS A 157 ALA A 103 VAL A 107	None	1.35A	2d06A-3cdlA: undetectable	2d06A-3cdlA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DQY_C_CHDC3_0 (LIVER CARBOXYLESTERASE 1)	3cdl	TRANSCRIPTIONAL REGULATOR AEFR (Pseudomonas syringae group genomosp. 3)	4 / 6	TRP A 195 LEU A 193 LEU A 144 VAL A 147	None	1.09A	2dqyC-3cdlA: undetectable	2dqyC-3cdlA: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRZ_B_ACTB1463_0 (DEOXYRIBODIPYRIMIDIN E PHOTOLYASE)	3cdl	TRANSCRIPTIONAL REGULATOR AEFR (Pseudomonas syringae group genomosp. 3)	4 / 7	VAL A 43 ILE A 32 ALA A 36 VAL A 38	None	0.52A	2xrzB-3cdlA: undetectable	2xrzB-3cdlA: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	3cdl	TRANSCRIPTIONAL REGULATOR AEFR (Pseudomonas syringae group genomosp. 3)	4 / 7	ARG A 143 LEU A 144 ALA A 152 GLN A 155	None	1.08A	6b89A-3cdlA: undetectable	6b89A-3cdlA: 20.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2D06_A_ESTA304_1","SULFOTRANSFERASE 1A1","3cdl","TRANSCRIPTIONAL REGULATOR AEFR","Pseudomonas syringae group genomosp. 3",5,"LYS A  90;LYS A 128;HIS A 157;ALA A 103;VAL A 107","None","1.35A","2d06A-3cdlA:undetectable","2d06A-3cdlA:21.16"],["2DQY_C_CHDC3_0","LIVER CARBOXYLESTERASE 1","3cdl","TRANSCRIPTIONAL REGULATOR AEFR","Pseudomonas syringae group genomosp. 3",4,"TRP A 195;LEU A 193;LEU A 144;VAL A 147","None","1.09A","2dqyC-3cdlA:undetectable","2dqyC-3cdlA:15.47"],["2XRZ_B_ACTB1463_0","DEOXYRIBODIPYRIMIDINE PHOTOLYASE","3cdl","TRANSCRIPTIONAL REGULATOR AEFR","Pseudomonas syringae group genomosp. 3",4,"VAL A  43;ILE A  32;ALA A  36;VAL A  38","None","0.52A","2xrzB-3cdlA:undetectable","2xrzB-3cdlA:18.12"],["6B89_B_NOVB403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","3cdl","TRANSCRIPTIONAL REGULATOR AEFR","Pseudomonas syringae group genomosp. 3",4,"ARG A 143;LEU A 144;ALA A 152;GLN A 155","None","1.08A","6b89A-3cdlA:undetectable","6b89A-3cdlA:20.40"]]