SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cdx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 11 GLY A  63
HIS A  62
ILE A  99
GLY A 110
SER A 126
 None
CA  A 401 (-3.4A)
None
None
None
 1.14A 1gtfQ-3cdxA:
undetectable
1gtfR-3cdxA:
undetectable		 1gtfQ-3cdxA:
11.68
1gtfR-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 11 GLY A  63
HIS A  62
ILE A  99
GLY A 110
SER A 126
 None
CA  A 401 (-3.4A)
None
None
None
 1.15A 1gtfS-3cdxA:
undetectable
1gtfT-3cdxA:
undetectable		 1gtfS-3cdxA:
11.68
1gtfT-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 224
VAL A 220
ALA A 183
GLY A  68
LEU A 210
 None
 1.03A 1kiaC-3cdxA:
undetectable		 1kiaC-3cdxA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 9 ASP A 112
GLY A 119
SER A 196
ASP A 146
THR A 199
 None
 1.35A 1m4gB-3cdxA:
undetectable		 1m4gB-3cdxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 224
VAL A 220
ALA A 183
GLY A  68
LEU A 210
 None
 1.04A 1nbhB-3cdxA:
undetectable		 1nbhB-3cdxA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A  63
HIS A  62
ILE A  99
GLY A 110
SER A 126
 None
CA  A 401 (-3.4A)
None
None
None
 1.12A 1utdE-3cdxA:
undetectable
1utdF-3cdxA:
undetectable		 1utdE-3cdxA:
11.68
1utdF-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 8 ARG A 226
GLY A 256
THR A 248
ALA A 249
ALA A 255
 None
 1.40A 2ej3A-3cdxA:
undetectable		 2ej3A-3cdxA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 8 ARG A 226
GLY A 256
THR A 248
ALA A 249
ALA A 255
 None
 1.40A 2ej3C-3cdxA:
undetectable		 2ej3C-3cdxA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H9T_H_SVRH301_1
(THROMBIN)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 11 ARG A 328
ARG A 273
VAL A 269
GLY A 315
GLU A 286
 None
 1.48A 2h9tH-3cdxA:
undetectable		 2h9tH-3cdxA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 11 HIS A 238
VAL A 241
GLY A 231
ILE A 232
VAL A  88
 None
 1.08A 2uxpB-3cdxA:
undetectable		 2uxpB-3cdxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 7 ASP A 146
HIS A 148
LEU A 133
ILE A  99
 None
CA  A 401 (-3.3A)
None
None
 0.98A 3avpA-3cdxA:
undetectable		 3avpA-3cdxA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  57
ALA A 177
ALA A 183
VAL A 241
MET A 239
 None
 1.03A 3czhB-3cdxA:
undetectable		 3czhB-3cdxA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 THR A 157
GLY A 215
ILE A 227
GLN A 250
THR A 257
 None
 1.12A 3eeyC-3cdxA:
undetectable		 3eeyC-3cdxA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 THR A 157
GLY A 215
ILE A 227
GLN A 250
THR A 257
 None
 1.12A 3eeyE-3cdxA:
undetectable		 3eeyE-3cdxA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 THR A 157
GLY A 215
ILE A 227
GLN A 250
THR A 257
 None
 1.14A 3eeyF-3cdxA:
undetectable		 3eeyF-3cdxA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 309
VAL A 326
GLY A 275
LEU A 307
PRO A 306
 None
 1.28A 3mecA-3cdxA:
undetectable		 3mecA-3cdxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		6 / 12 ASN A 114
LEU A  91
GLU A  65
GLY A  68
ILE A  42
VAL A  61
 None
None
CA  A 401 (-2.0A)
None
None
None
 1.31A 3nk7A-3cdxA:
undetectable		 3nk7A-3cdxA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		6 / 12 ASN A 114
LEU A  91
GLU A  65
GLY A  68
ILE A  42
VAL A  61
 None
None
CA  A 401 (-2.0A)
None
None
None
 1.27A 3nk7B-3cdxA:
undetectable		 3nk7B-3cdxA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		6 / 12 ASN A 114
LEU A  91
GLY A  59
GLU A  65
GLY A  68
VAL A  61
 None
None
None
CA  A 401 (-2.0A)
None
None
 1.48A 3nk7B-3cdxA:
undetectable		 3nk7B-3cdxA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 7 ASP A 109
VAL A  40
ILE A  42
SER A 106
 None
 0.94A 3pglA-3cdxA:
undetectable		 3pglA-3cdxA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 10 THR A 160
ASN A 186
HIS A 259
GLY A 182
ALA A 183
 None
 1.35A 3pp7B-3cdxA:
undetectable		 3pp7B-3cdxA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 8 ALA A 271
ILE A 296
LEU A 309
ALA A 321
 None
 0.69A 3r9tA-3cdxA:
undetectable		 3r9tA-3cdxA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		6 / 10 GLY A  68
ALA A  71
ASP A  74
ILE A 227
VAL A 235
ILE A 232
 None
 1.11A 4dqfB-3cdxA:
undetectable		 4dqfB-3cdxA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  30
VAL A 108
PRO A  97
THR A  58
GLY A  59
 None
 1.18A 4hvcB-3cdxA:
undetectable		 4hvcB-3cdxA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 ASP A 330
THR A 327
GLY A 110
SER A 153
TYR A 154
 None
 1.29A 4kn2A-3cdxA:
undetectable		 4kn2A-3cdxA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_B_LYAB304_1
(FOLATE RECEPTOR BETA)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 ASP A 330
THR A 327
GLY A 110
SER A 153
TYR A 154
 None
 1.29A 4kn2B-3cdxA:
undetectable		 4kn2B-3cdxA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 ASP A 330
THR A 327
GLY A 110
SER A 153
TYR A 154
 None
 1.29A 4kn2C-3cdxA:
undetectable		 4kn2C-3cdxA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 VAL A 187
GLU A  65
HIS A  62
THR A  58
GLY A  60
 None
CA  A 401 (-2.0A)
CA  A 401 (-3.4A)
None
None
 1.45A 4olfA-3cdxA:
undetectable		 4olfA-3cdxA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 8 ALA A 130
GLY A 123
VAL A 108
SER A 106
 None
 0.78A 4r20A-3cdxA:
undetectable		 4r20A-3cdxA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 11 GLY A 151
ASP A 112
ILE A 113
ASN A 114
TYR A  66
 None
 1.32A 4rtrA-3cdxA:
undetectable		 4rtrA-3cdxA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 11 GLY A 151
ASP A 112
ILE A 113
SER A 126
TYR A  66
 None
 1.45A 4rtrA-3cdxA:
undetectable		 4rtrA-3cdxA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 151
ASP A 112
ILE A 113
ASN A 114
TYR A  66
 None
 1.24A 4rtsA-3cdxA:
undetectable		 4rtsA-3cdxA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 6 TYR A  66
HIS A 152
GLY A 216
ARG A 219
 None
 1.22A 4zbqA-3cdxA:
undetectable		 4zbqA-3cdxA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A  60
GLY A  59
THR A  58
GLU A  65
ILE A 113
 None
None
None
CA  A 401 (-2.0A)
None
 1.22A 4zvmA-3cdxA:
2.0
4zvmB-3cdxA:
2.2		 4zvmA-3cdxA:
21.10
4zvmB-3cdxA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 110
SER A 126
GLY A  63
HIS A  62
ILE A  99
 None
None
None
CA  A 401 (-3.4A)
None
 1.12A 5ef0A-3cdxA:
undetectable
5ef0B-3cdxA:
undetectable		 5ef0A-3cdxA:
11.68
5ef0B-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 110
SER A 126
GLY A  63
HIS A  62
ILE A  99
 None
None
None
CA  A 401 (-3.4A)
None
 1.12A 5ef1A-3cdxA:
undetectable
5ef1B-3cdxA:
undetectable		 5ef1A-3cdxA:
11.68
5ef1B-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 110
SER A 126
GLY A  63
HIS A  62
ILE A  99
 None
None
None
CA  A 401 (-3.4A)
None
 1.12A 5ef2A-3cdxA:
undetectable
5ef2B-3cdxA:
undetectable		 5ef2A-3cdxA:
11.68
5ef2B-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 110
SER A 126
GLY A  63
HIS A  62
ILE A  99
 None
None
None
CA  A 401 (-3.4A)
None
 1.11A 5ef3A-3cdxA:
undetectable
5ef3B-3cdxA:
undetectable		 5ef3A-3cdxA:
11.68
5ef3B-3cdxA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 7 VAL A 332
ALA A 321
GLY A 324
VAL A 326
 None
 0.93A 5fpdA-3cdxA:
undetectable		 5fpdA-3cdxA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 7 ASN A 161
SER A 159
ALA A 183
GLY A 228
 None
 0.82A 5fpdB-3cdxA:
undetectable		 5fpdB-3cdxA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 7 VAL A 332
ALA A 321
GLY A 324
VAL A 326
 None
 0.93A 5fpdB-3cdxA:
undetectable		 5fpdB-3cdxA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 ASN A 221
GLY A 224
ASP A 155
VAL A 317
SER A 159
 None
 1.00A 5vopA-3cdxA:
undetectable		 5vopA-3cdxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  30
VAL A 108
PRO A  97
THR A  58
GLY A  59
 None
 1.23A 5xipA-3cdxA:
undetectable		 5xipA-3cdxA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  30
VAL A 108
PRO A  97
THR A  58
GLY A  59
 None
 1.15A 5xipC-3cdxA:
undetectable		 5xipC-3cdxA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  30
VAL A 108
PRO A  97
THR A  58
GLY A  59
 None
 1.15A 5xiqA-3cdxA:
undetectable		 5xiqA-3cdxA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  30
VAL A 108
PRO A  97
THR A  58
GLY A  59
 None
 1.14A 5xiqD-3cdxA:
undetectable		 5xiqD-3cdxA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  79
LEU A 236
ASN A 234
ILE A  72
ALA A  71
 None
 1.00A 5xiwB-3cdxA:
undetectable		 5xiwB-3cdxA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 6 ASP A  64
ARG A 104
ASP A 112
CYH A 116
 None
CA  A 401 ( 4.2A)
None
None
 0.89A 6mn5D-3cdxA:
undetectable		 6mn5D-3cdxA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		4 / 7 ASP A  64
ARG A 104
ASP A 112
CYH A 116
 None
CA  A 401 ( 4.2A)
None
None
 1.10A 6mn5E-3cdxA:
undetectable		 6mn5E-3cdxA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE
(Rhodobacter
sphaeroides) 		5 / 12 VAL A 187
GLU A  65
HIS A  62
THR A  58
GLY A  60
 None
CA  A 401 (-2.0A)
CA  A 401 (-3.4A)
None
None
 1.39A 6mn8A-3cdxA:
undetectable		 6mn8A-3cdxA:
21.40