SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ce2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 8 PHE A 425
ALA A 542
PHE A 546
ILE A 541
 None
 0.97A 1gm7A-3ce2A:
undetectable
1gm7B-3ce2A:
undetectable		 1gm7A-3ce2A:
15.90
1gm7B-3ce2A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		5 / 12 MET A 442
SER A 338
LEU A 339
LEU A 334
THR A 391
 None
 1.48A 1ya3B-3ce2A:
undetectable		 1ya3B-3ce2A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 7 ALA A 256
TYR A 261
TYR A 534
TYR A 279
 None
 1.05A 2ajvH-3ce2A:
undetectable
2ajvL-3ce2A:
undetectable		 2ajvH-3ce2A:
17.31
2ajvL-3ce2A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		5 / 12 ALA A 372
HIS A 400
GLU A 401
HIS A 404
GLU A 428
 None
ZN  A 703 (-3.3A)
ZN  A 703 ( 4.7A)
ZN  A 703 (-3.4A)
ZN  A 703 (-2.9A)
 0.65A 2c6nA-3ce2A:
16.8		 2c6nA-3ce2A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 6 ASP A 479
ASP A 284
THR A 280
LYS A 287
 None
 1.03A 2j2pE-3ce2A:
undetectable
2j2pF-3ce2A:
undetectable		 2j2pE-3ce2A:
15.88
2j2pF-3ce2A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		3 / 3 GLU A 232
ASP A 514
TYR A 312
 None
 0.61A 2yvlB-3ce2A:
undetectable		 2yvlB-3ce2A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 8 LEU A 472
GLN A 470
PHE A 506
LEU A 502
 None
 0.99A 3asoC-3ce2A:
3.5
3asoJ-3ce2A:
undetectable		 3asoC-3ce2A:
18.99
3asoJ-3ce2A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		3 / 3 HIS A 481
GLU A 485
HIS A 482
 None
None
ZN  A 701 (-3.4A)
 0.88A 3ba0A-3ce2A:
undetectable		 3ba0A-3ce2A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		3 / 3 HIS A 400
GLU A 401
HIS A 404
 ZN  A 703 (-3.3A)
ZN  A 703 ( 4.7A)
ZN  A 703 (-3.4A)
 0.12A 3kecB-3ce2A:
undetectable		 3kecB-3ce2A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 6 SER A 475
THR A 280
ILE A 283
THR A 498
 None
 1.05A 4acbC-3ce2A:
undetectable		 4acbC-3ce2A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 8 SER A  40
GLU A 100
ASP A 104
TYR A  28
 None
 1.07A 4qb9D-3ce2A:
undetectable		 4qb9D-3ce2A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		5 / 12 LEU A 350
GLN A 352
ILE A 398
VAL A 360
VAL A 384
 None
 1.08A 5dpdA-3ce2A:
undetectable		 5dpdA-3ce2A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		3 / 3 SER A 375
LEU A 350
MET A 406
 None
 0.78A 5ikrB-3ce2A:
1.6		 5ikrB-3ce2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 6 LEU A 150
PHE A 154
HIS A 137
PHE A 417
 None
 0.92A 5vkqB-3ce2A:
2.7
5vkqC-3ce2A:
2.7		 5vkqB-3ce2A:
16.42
5vkqC-3ce2A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 6 LEU A 150
PHE A 154
HIS A 137
PHE A 417
 None
 0.93A 5vkqC-3ce2A:
2.7
5vkqD-3ce2A:
2.7		 5vkqC-3ce2A:
16.42
5vkqD-3ce2A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		5 / 12 TYR A 326
ILE A 335
LEU A 438
GLY A 390
LEU A 392
 None
 1.19A 5zwrA-3ce2A:
undetectable		 5zwrA-3ce2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		3 / 3 TYR A 561
HIS A 407
MET A 406
 None
 1.03A 6af6A-3ce2A:
2.5		 6af6A-3ce2A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		5 / 12 HIS A 381
VAL A  86
ARG A  13
PHE A 328
GLY A 358
 None
 1.35A 6brdA-3ce2A:
undetectable		 6brdA-3ce2A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 4 GLN A 535
THR A 538
THR A 277
LEU A 574
 None
 1.48A 6f3mA-3ce2A:
undetectable		 6f3mA-3ce2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		4 / 4 GLN A 535
THR A 538
THR A 277
LEU A 574
 None
 1.46A 6f3mC-3ce2A:
undetectable		 6f3mC-3ce2A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		3 / 3 LEU A  74
SER A  76
PHE A  75
 None
 0.58A 6fgcA-3ce2A:
undetectable		 6fgcA-3ce2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3ce2 PUTATIVE PEPTIDASE
(Chlamydia
abortus) 		5 / 12 LEU A 245
ILE A 524
ALA A 483
LEU A 472
ASP A 479
 None
 1.22A 6ie8A-3ce2A:
undetectable		 6ie8A-3ce2A:
16.23