SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ced'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 7 PHE A 270
LEU A 309
LEU A 311
ARG A 331
 None
 0.99A 2jn3A-3cedA:
undetectable		 2jn3A-3cedA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		3 / 3 LEU A 309
LEU A 268
ARG A 331
 None
 0.50A 3hcnB-3cedA:
undetectable		 3hcnB-3cedA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 7 ILE A 313
ARG A 267
MET A 335
LEU A 328
 None
 0.92A 5b1aA-3cedA:
undetectable
5b1aJ-3cedA:
undetectable		 5b1aA-3cedA:
11.49
5b1aJ-3cedA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 7 ILE A 313
ARG A 267
MET A 335
LEU A 328
 None
 0.93A 5b3sA-3cedA:
undetectable
5b3sJ-3cedA:
undetectable		 5b3sA-3cedA:
11.49
5b3sJ-3cedA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 5 TYR A 287
ILE A 289
GLY A 322
PHE A 321
 None
 0.70A 5kmdC-3cedA:
undetectable
5kmdD-3cedA:
undetectable		 5kmdC-3cedA:
15.09
5kmdD-3cedA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 6 GLY A 322
PHE A 321
TYR A 287
ILE A 289
 None
 0.91A 5kmfA-3cedA:
undetectable
5kmfC-3cedA:
undetectable		 5kmfA-3cedA:
15.09
5kmfC-3cedA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		5 / 10 VAL A 333
LEU A 311
ARG A 267
GLY A 307
PHE A 270
 None
 1.21A 5mxbA-3cedA:
undetectable		 5mxbA-3cedA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 7 ILE A 313
ARG A 267
MET A 335
LEU A 328
 None
 0.96A 5zcpA-3cedA:
undetectable
5zcpJ-3cedA:
undetectable		 5zcpA-3cedA:
11.49
5zcpJ-3cedA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ced METHIONINE IMPORT
ATP-BINDING PROTEIN
METN 2
(Staphylococcus
aureus) 		4 / 7 ILE A 313
ARG A 267
MET A 335
LEU A 328
 None
 0.97A 5zcqA-3cedA:
undetectable
5zcqJ-3cedA:
undetectable		 5zcqA-3cedA:
11.49
5zcqJ-3cedA:
24.36