SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ceg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3ceg BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 7 ALA A4706
THR A4707
ALA A4711
PRO A4592
 None
 0.89A 2ql8A-3cegA:
undetectable
2ql8B-3cegA:
undetectable		 2ql8A-3cegA:
16.51
2ql8B-3cegA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 3ceg BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 4 VAL A4625
TYR A4699
PRO A4592
PHE A4627
 None
 1.23A 3d91B-3cegA:
0.0		 3d91B-3cegA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 3ceg BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 5 GLY A4688
ARG A4687
GLU A4675
PHE A4678
 None
 1.27A 4r82A-3cegA:
undetectable
4r82B-3cegA:
undetectable		 4r82A-3cegA:
20.13
4r82B-3cegA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ceg BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 6
(Homo
sapiens) 		4 / 6 TYR A4603
PRO A4613
LEU A4550
TYR A4608
 None
 1.27A 4z4cA-3cegA:
undetectable		 4z4cA-3cegA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3ceg BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 6
(Homo
sapiens) 		5 / 12 ILE A4703
LEU A4769
VAL A4708
THR A4619
LEU A4617
 None
 1.24A 6b54A-3cegA:
undetectable		 6b54A-3cegA:
20.06