SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 5 LEU A 139
SER A 808
LEU A 683
GLY A 485
NBG  A   1 ( 4.2A)
None
None
None
1.05A 1a4lB-3cemA:
undetectable
1a4lB-3cemA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 4 THR A 240
PRO A 229
THR A 228
PRO A 231
None
1.37A 1a7yA-3cemA:
undetectable
1a7yC-3cemA:
undetectable
1a7yA-3cemA:
2.15
1a7yC-3cemA:
2.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.78A 1c8lA-3cemA:
67.4
1c8lA-3cemA:
80.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.81A 1gfzA-3cemA:
65.8
1gfzA-3cemA:
80.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
None
0.29A 1l5qA-3cemA:
58.7
1l5qA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
None
0.84A 1l5qA-3cemA:
58.7
1l5qA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 4 TRP A 174
HIS A 614
LYS A 617
MET A 618
None
0.22A 1l5qA-3cemA:
58.7
1l5qA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
None
0.35A 1l5qB-3cemA:
58.5
1l5qB-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
None
0.84A 1l5qB-3cemA:
58.5
1l5qB-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
3 / 3 TRP A 174
HIS A 614
MET A 618
None
0.27A 1l5qB-3cemA:
58.5
1l5qB-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
10 / 11 ASN A 282
PHE A 285
LEU A 380
GLU A 382
TYR A 573
ALA A 610
GLY A 612
TYR A 613
ARG A 770
PHE A 771
None
0.66A 1l5rA-3cemA:
58.5
1l5rA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
7 / 11 ASN A 282
PHE A 285
LEU A 380
HIS A 571
TYR A 573
ALA A 610
GLY A 612
None
1.14A 1l5rA-3cemA:
58.5
1l5rA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 11 TYR A 573
ALA A 609
TYR A 613
ARG A 770
PHE A 771
None
1.37A 1l5rA-3cemA:
58.5
1l5rA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
None
0.35A 1l7xA-3cemA:
58.8
1l7xA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
None
0.89A 1l7xA-3cemA:
58.8
1l7xA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
3 / 3 TRP A 174
HIS A 614
LYS A 617
None
0.25A 1l7xA-3cemA:
58.8
1l7xA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
None
0.39A 1l7xB-3cemA:
58.0
1l7xB-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
None
0.90A 1l7xB-3cemA:
58.0
1l7xB-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_A_ACRA992_1
(MALTODEXTRIN
PHOSPHORYLASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 10 ASN A 133
LEU A 136
ASP A 339
HIS A 341
HIS A 571
ALA A 610
None
NBG  A   1 (-4.1A)
None
None
None
None
0.99A 2ecpA-3cemA:
54.7
2ecpA-3cemA:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_B_ACRB992_1
(MALTODEXTRIN
PHOSPHORYLASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 10 ASN A 133
LEU A 136
ASP A 339
HIS A 341
HIS A 571
ALA A 610
None
NBG  A   1 (-4.1A)
None
None
None
None
0.96A 2ecpB-3cemA:
53.4
2ecpB-3cemA:
44.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
3 / 3 ASN A 133
LEU A 136
HIS A 341
None
NBG  A   1 (-4.1A)
None
0.87A 2q6fB-3cemA:
undetectable
2q6fB-3cemA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 11 LEU A 425
ARG A 427
ILE A 414
LEU A 474
ASP A 470
None
1.23A 2q6hA-3cemA:
0.5
2q6hA-3cemA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 ASP A 306
PHE A 196
TYR A  83
THR A 240
AVD  A 833 ( 4.9A)
AVD  A 833 (-4.2A)
None
None
1.39A 2q6kA-3cemA:
undetectable
2q6kA-3cemA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 11 LEU A 425
ARG A 427
ILE A 414
LEU A 474
ASP A 470
None
1.26A 2qeiA-3cemA:
1.8
2qeiA-3cemA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 6 LEU A 117
PHE A  31
LEU A  55
ASP A  50
None
0.66A 2wm3A-3cemA:
4.2
2wm3A-3cemA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 6 VAL A 455
ASP A 339
TYR A  84
ASN A 484
NBG  A   1 ( 4.5A)
None
None
NBG  A   1 (-3.3A)
1.47A 2zs9A-3cemA:
undetectable
2zs9A-3cemA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 8 GLY A 675
THR A 676
GLU A 672
GLY A 694
ALA A 695
PLP  A 832 ( 3.3A)
PLP  A 832 (-3.8A)
NBG  A   1 (-3.5A)
None
None
1.14A 3aruA-3cemA:
undetectable
3aruA-3cemA:
21.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 5 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
None
0.22A 3bcrA-3cemA:
66.9
3bcrA-3cemA:
80.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.86A 3dd1A-3cemA:
57.5
3dd1A-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.86A 3dd1B-3cemA:
58.7
3dd1B-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.88A 3ddsA-3cemA:
57.4
3ddsA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.87A 3ddsB-3cemA:
58.5
3ddsB-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.88A 3ddwA-3cemA:
57.6
3ddwA-3cemA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.89A 3ddwB-3cemA:
58.9
3ddwB-3cemA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 5 LEU A 502
LYS A 538
LEU A 534
GLU A 533
None
1.16A 3h5gA-3cemA:
undetectable
3h5gB-3cemA:
undetectable
3h5gA-3cemA:
3.09
3h5gB-3cemA:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 6 SER A 146
GLY A 809
GLU A 701
GLU A 702
None
1.12A 3k9fA-3cemA:
undetectable
3k9fB-3cemA:
undetectable
3k9fD-3cemA:
2.2
3k9fA-3cemA:
21.00
3k9fB-3cemA:
21.00
3k9fD-3cemA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
3 / 3 ASN A 440
ASN A 407
GLU A 433
None
0.69A 3kpdC-3cemA:
undetectable
3kpdC-3cemA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 6 SER A 812
LEU A 683
THR A 487
ARG A 489
None
1.35A 3thrB-3cemA:
2.8
3thrB-3cemA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 12 THR A 487
PHE A 811
GLY A 809
GLY A 677
ASN A 696
None
None
None
PLP  A 832 (-3.8A)
None
1.27A 3v3oA-3cemA:
2.1
3v3oA-3cemA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 6 PHE A 479
LEU A 474
PRO A 476
GLU A 473
None
1.41A 3vlnA-3cemA:
undetectable
3vlnA-3cemA:
15.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 8 TRP A 361
ARG A 398
GLU A 401
GLU A 405
None
0.35A 4bqfB-3cemA:
55.4
4bqfB-3cemA:
44.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 8 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.10A 4d33A-3cemA:
undetectable
4d33A-3cemA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.09A 4d33B-3cemA:
undetectable
4d33B-3cemA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 8 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.02A 4d39A-3cemA:
undetectable
4d39A-3cemA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.09A 4d39B-3cemA:
undetectable
4d39B-3cemA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EBK_B_TOYB302_1
(AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 9 GLU A 572
TYR A 613
ALA A 616
GLU A 382
ASP A 283
None
None
None
None
NBG  A   1 ( 4.5A)
1.46A 4ebkA-3cemA:
0.4
4ebkB-3cemA:
0.4
4ebkA-3cemA:
15.98
4ebkB-3cemA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 8 ASN A 481
PHE A 479
VAL A 452
HIS A 459
ALA A 673
None
None
None
None
NBG  A   1 (-3.7A)
1.41A 4eyzA-3cemA:
undetectable
4eyzA-3cemA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 8 ASN A 481
PHE A 479
VAL A 452
HIS A 459
ALA A 673
None
None
None
None
NBG  A   1 (-3.7A)
1.40A 4eyzB-3cemA:
undetectable
4eyzB-3cemA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 11 ILE A 119
ALA A  54
LEU A  55
THR A  58
VAL A  59
None
0.94A 4g1bB-3cemA:
3.4
4g1bB-3cemA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
3 / 3 ASP A 331
LYS A 324
LEU A 359
None
1.08A 4ptjA-3cemA:
undetectable
4ptjA-3cemA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 9 ILE A 657
ASN A 541
LEU A 534
LEU A 492
ILE A 503
None
1.24A 4r38C-3cemA:
undetectable
4r38C-3cemA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 ASN A 101
TYR A  52
LEU A  55
PHE A  31
None
1.24A 4yv5A-3cemA:
undetectable
4yv5A-3cemA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 12 ALA A 140
GLY A 132
GLY A 137
GLY A 135
LEU A 131
None
None
None
PLP  A 832 (-3.9A)
None
0.81A 5c0oH-3cemA:
2.3
5c0oH-3cemA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 6 SER A 245
ASP A 181
ARG A 184
GLY A 186
None
1.07A 5cdqA-3cemA:
undetectable
5cdqC-3cemA:
undetectable
5cdqD-3cemA:
undetectable
5cdqA-3cemA:
21.32
5cdqC-3cemA:
21.32
5cdqD-3cemA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_D_EVPD102_1
(DNA TOPOISOMERASE
2-ALPHA)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 4 GLY A 130
ASP A 180
ARG A 649
MET A  99
None
1.43A 5gwkB-3cemA:
1.2
5gwkB-3cemA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 8 TYR A  84
PHE A 143
ILE A 824
TRP A 825
None
0.89A 5hw8H-3cemA:
undetectable
5hw8H-3cemA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
3 / 3 LYS A 608
ASP A 283
ILE A 623
None
NBG  A   1 ( 4.5A)
None
0.75A 5kc4E-3cemA:
undetectable
5kc4E-3cemA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 4 GLN A 219
THR A 218
LEU A 293
LEU A 395
None
1.25A 5m5kB-3cemA:
3.9
5m5kB-3cemA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 LEU A 652
ILE A 125
GLU A 124
ASP A 128
None
0.91A 5n5dA-3cemA:
3.2
5n5dA-3cemA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
7 / 10 GLY A 135
HIS A 377
VAL A 455
ASN A 484
LYS A 574
GLU A 672
GLY A 675
PLP  A 832 (-3.9A)
NBG  A   1 (-3.8A)
NBG  A   1 ( 4.5A)
NBG  A   1 (-3.3A)
PLP  A 832 (-2.8A)
NBG  A   1 (-3.5A)
PLP  A 832 ( 3.3A)
0.70A 5vncC-3cemA:
17.5
5vncC-3cemA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 10 LEU A 396
LEU A 349
LEU A 337
ALA A 343
LEU A 444
None
1.26A 5y7pB-3cemA:
undetectable
5y7pB-3cemA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 12 LEU A 581
PHE A 750
PHE A 749
LEU A 622
VAL A 626
None
1.31A 6a93B-3cemA:
undetectable
6a93B-3cemA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 ARG A 310
TYR A 157
LEU A 144
TYR A  83
AVD  A 833 (-4.0A)
None
None
None
1.36A 6g2pA-3cemA:
2.7
6g2pA-3cemA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 12 GLY A 134
GLY A 135
ASP A 339
VAL A 455
ASN A 484
GLY A 675
PLP  A 832 (-3.6A)
PLP  A 832 (-3.9A)
None
NBG  A   1 ( 4.5A)
NBG  A   1 (-3.3A)
PLP  A 832 ( 3.3A)
0.74A 6gneA-3cemA:
23.4
6gneA-3cemA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 12 GLU A  88
GLY A 134
GLY A 135
VAL A 455
ASN A 484
GLY A 675
None
PLP  A 832 (-3.6A)
PLP  A 832 (-3.9A)
NBG  A   1 ( 4.5A)
NBG  A   1 (-3.3A)
PLP  A 832 ( 3.3A)
0.70A 6gneB-3cemA:
23.2
6gneB-3cemA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 12 GLU A  88
GLY A 135
ASP A 339
VAL A 455
ASN A 484
GLY A 675
None
PLP  A 832 (-3.9A)
None
NBG  A   1 ( 4.5A)
NBG  A   1 (-3.3A)
PLP  A 832 ( 3.3A)
0.80A 6gneB-3cemA:
23.2
6gneB-3cemA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 12 ASP A 339
HIS A 341
ASN A 484
GLU A 672
GLY A 675
None
None
NBG  A   1 (-3.3A)
NBG  A   1 (-3.5A)
PLP  A 832 ( 3.3A)
0.77A 6gnfA-3cemA:
22.9
6gnfA-3cemA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 12 ASP A 339
HIS A 341
ASN A 484
GLU A 672
GLY A 675
None
None
NBG  A   1 (-3.3A)
NBG  A   1 (-3.5A)
PLP  A 832 ( 3.3A)
0.76A 6gnfC-3cemA:
23.2
6gnfC-3cemA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
5 / 12 GLY A 134
LEU A 136
ASP A 339
HIS A 341
ASN A 484
PLP  A 832 (-3.6A)
NBG  A   1 (-4.1A)
None
None
NBG  A   1 (-3.3A)
0.89A 6gngA-3cemA:
22.2
6gngA-3cemA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 12 GLU A  88
GLY A 135
HIS A 377
VAL A 455
GLU A 672
GLY A 675
None
PLP  A 832 (-3.9A)
NBG  A   1 (-3.8A)
NBG  A   1 ( 4.5A)
NBG  A   1 (-3.5A)
PLP  A 832 ( 3.3A)
0.64A 6gngA-3cemA:
22.2
6gngA-3cemA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 12 GLU A  88
GLY A 134
GLY A 135
LEU A 136
HIS A 341
ARG A 569
None
PLP  A 832 (-3.6A)
PLP  A 832 (-3.9A)
NBG  A   1 (-4.1A)
None
None
1.47A 6gngB-3cemA:
22.2
6gngB-3cemA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
6 / 12 GLU A  88
GLY A 134
GLY A 135
LEU A 136
HIS A 341
ASN A 284
None
PLP  A 832 (-3.6A)
PLP  A 832 (-3.9A)
NBG  A   1 (-4.1A)
None
NBG  A   1 (-3.5A)
1.30A 6gngB-3cemA:
22.2
6gngB-3cemA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 8 VAL A 781
GLN A 566
ILE A 689
GLU A 664
None
0.95A 6hzpA-3cemA:
undetectable
6hzpA-3cemA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 5 GLY A 137
LEU A 136
SER A  86
TYR A  84
None
NBG  A   1 (-4.1A)
None
None
0.96A 6ji6A-3cemA:
undetectable
6ji6A-3cemA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo
sapiens)
4 / 7 ARG A 398
ALA A 364
THR A 368
ILE A 346
None
0.96A 6ma7A-3cemA:
undetectable
6ma7A-3cemA:
7.43