SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ceu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 176
GLU A  15
ILE A  19
LEU A 172
 None
 1.46A 1q0yH-3ceuA:
undetectable
1q0yL-3ceuA:
undetectable		 1q0yH-3ceuA:
20.00
1q0yL-3ceuA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 8 GLU A  15
LEU A  45
SER A  42
PHE A  11
THR A  37
 None
 1.44A 3ax9A-3ceuA:
undetectable		 3ax9A-3ceuA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  19
LEU A  22
LEU A  27
VAL A   5
THR A   7
 None
 1.04A 3dcjA-3ceuA:
undetectable
3dcjB-3ceuA:
undetectable		 3dcjA-3ceuA:
20.09
3dcjB-3ceuA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 150
PHE A 112
GLY A 173
LEU A 175
PHE A 194
 None
 1.29A 3tbgA-3ceuA:
undetectable		 3tbgA-3ceuA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 GLU A  15
LEU A  45
SER A  42
PHE A  11
THR A  37
 None
 1.44A 3unaB-3ceuA:
undetectable		 3unaB-3ceuA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A  27
ASP A  28
ILE A  57
ILE A   4
PHE A  23
 None
 1.00A 4odrA-3ceuA:
undetectable
4odrB-3ceuA:
undetectable		 4odrA-3ceuA:
20.81
4odrB-3ceuA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A  27
ASP A  28
ILE A  57
ILE A   4
PHE A  23
 None
 1.02A 4odrA-3ceuA:
undetectable
4odrB-3ceuA:
undetectable		 4odrA-3ceuA:
20.81
4odrB-3ceuA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 166
ARG A 135
ALA A 131
LEU A 134
 None
 1.04A 4rkuA-3ceuA:
undetectable
4rkuJ-3ceuA:
undetectable		 4rkuA-3ceuA:
14.48
4rkuJ-3ceuA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 166
ARG A 135
ALA A 131
LEU A 134
 None
 1.08A 4xk8A-3ceuA:
undetectable		 4xk8A-3ceuA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ALA A  78
HIS A  75
ARG A  79
HIS A  96
 None
 1.26A 5db5A-3ceuA:
undetectable
5db5B-3ceuA:
undetectable		 5db5A-3ceuA:
17.80
5db5B-3ceuA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 164
ILE A 116
GLY A 168
PHE A 166
 None
 0.85A 5h3aA-3ceuA:
undetectable		 5h3aA-3ceuA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3ceu THIAMINE PHOSPHATE
PYROPHOSPHORYLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 158
GLY A 173
ILE A 153
ASN A 154
VAL A 170
 None
 1.37A 5hjiA-3ceuA:
2.0		 5hjiA-3ceuA:
21.25