SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cew'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_A_SPMA202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	3cew	UNCHARACTERIZED CUPIN PROTEIN (Bacteroides fragilis)	4 / 8	TRP A 75 ILE A 51 GLU A 49 ILE A 54	None	0.94A	4mj8A-3cewA: undetectable	4mj8A-3cewA: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYQ_A_3CJA607_1 (LACTOPEROXIDASE)	3cew	UNCHARACTERIZED CUPIN PROTEIN (Bacteroides fragilis)	3 / 3	GLN A 100 HIS A 45 ARG A 84	ZN A 201 ( 4.8A) ZN A 201 (-3.4A) None	1.04A	4qyqA-3cewA: undetectable	4qyqA-3cewA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYQ_B_3CJB607_1 (LACTOPEROXIDASE)	3cew	UNCHARACTERIZED CUPIN PROTEIN (Bacteroides fragilis)	3 / 3	GLN A 100 HIS A 45 ARG A 84	ZN A 201 ( 4.8A) ZN A 201 (-3.4A) None	1.00A	4qyqB-3cewA: undetectable	4qyqB-3cewA: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PAH_A_LDPA600_1 (PHENYLALANINE 4-MONOOXYGENASE)	3cew	UNCHARACTERIZED CUPIN PROTEIN (Bacteroides fragilis)	4 / 4	HIS A 45 HIS A 43 TYR A 52 GLU A 50	ZN A 201 (-3.4A) ZN A 201 (-3.5A) None ZN A 201 (-2.2A)	1.34A	5pahA-3cewA: undetectable	5pahA-3cewA: 17.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4MJ8_A_SPMA202_1","SPERMIDINE N1-ACETYLTRANSFERASE","3cew","UNCHARACTERIZED CUPIN PROTEIN","Bacteroides fragilis",4,"TRP A  75;ILE A  51;GLU A  49;ILE A  54","None","0.94A","4mj8A-3cewA:undetectable","4mj8A-3cewA:21.67"],["4QYQ_A_3CJA607_1","LACTOPEROXIDASE","3cew","UNCHARACTERIZED CUPIN PROTEIN","Bacteroides fragilis",3,"GLN A 100;HIS A  45;ARG A  84"," ZN A 201 ( 4.8A); ZN A 201 (-3.4A);None","1.04A","4qyqA-3cewA:undetectable","4qyqA-3cewA:11.00"],["4QYQ_B_3CJB607_1","LACTOPEROXIDASE","3cew","UNCHARACTERIZED CUPIN PROTEIN","Bacteroides fragilis",3,"GLN A 100;HIS A  45;ARG A  84"," ZN A 201 ( 4.8A); ZN A 201 (-3.4A);None","1.00A","4qyqB-3cewA:undetectable","4qyqB-3cewA:11.00"],["5PAH_A_LDPA600_1","PHENYLALANINE 4-MONOOXYGENASE","3cew","UNCHARACTERIZED CUPIN PROTEIN","Bacteroides fragilis",4,"HIS A  45;HIS A  43;TYR A  52;GLU A  50"," ZN A 201 (-3.4A); ZN A 201 (-3.5A);None; ZN A 201 (-2.2A)","1.34A","5pahA-3cewA:undetectable","5pahA-3cewA:17.86"]]