SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 PHE A 618
ILE A 620
LEU A 492
VAL A 514
 None
 0.82A 1fslA-3cf0A:
undetectable		 1fslA-3cf0A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 PRO A 648
PRO A 520
GLY A 521
CYH A 522
 None
ADP  A 900 ( 4.9A)
ADP  A 900 (-3.4A)
None
 0.85A 1h4oB-3cf0A:
undetectable		 1h4oB-3cf0A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 PRO A 648
PRO A 520
GLY A 521
CYH A 522
 None
ADP  A 900 ( 4.9A)
ADP  A 900 (-3.4A)
None
 0.82A 1h4oG-3cf0A:
undetectable		 1h4oG-3cf0A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ASP A 669
PHE A 736
VAL A 666
 None
 0.77A 1kijB-3cf0A:
undetectable		 1kijB-3cf0A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 PRO A 648
PRO A 520
GLY A 521
CYH A 522
 None
ADP  A 900 ( 4.9A)
ADP  A 900 (-3.4A)
None
 0.85A 1oc3A-3cf0A:
undetectable		 1oc3A-3cf0A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 ALA A 530
LEU A 527
GLY A 523
GLY A 480
 None
None
ADP  A 900 (-2.8A)
ADP  A 900 (-3.7A)
 0.87A 1rukH-3cf0A:
undetectable
1rukL-3cf0A:
undetectable		 1rukH-3cf0A:
19.80
1rukL-3cf0A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		5 / 9 GLU A 546
ILE A 542
ILE A 540
GLU A 561
ILE A 562
 None
 1.29A 2j9dA-3cf0A:
0.0
2j9dB-3cf0A:
0.2
2j9dC-3cf0A:
0.0		 2j9dA-3cf0A:
21.63
2j9dB-3cf0A:
21.63
2j9dC-3cf0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		5 / 10 GLU A 546
ILE A 542
GLU A 466
GLU A 561
ILE A 562
 None
 1.39A 2j9dD-3cf0A:
undetectable
2j9dE-3cf0A:
undetectable
2j9dF-3cf0A:
undetectable		 2j9dD-3cf0A:
21.63
2j9dE-3cf0A:
21.63
2j9dF-3cf0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		5 / 10 GLU A 546
ILE A 542
ILE A 540
GLU A 561
ILE A 562
 None
 1.33A 2j9dD-3cf0A:
undetectable
2j9dE-3cf0A:
undetectable
2j9dF-3cf0A:
undetectable		 2j9dD-3cf0A:
21.63
2j9dE-3cf0A:
21.63
2j9dF-3cf0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		5 / 10 GLU A 561
ILE A 562
GLU A 546
ILE A 542
ILE A 540
 None
 1.34A 2j9dD-3cf0A:
undetectable
2j9dE-3cf0A:
undetectable
2j9dF-3cf0A:
undetectable		 2j9dD-3cf0A:
21.63
2j9dE-3cf0A:
21.63
2j9dF-3cf0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 ASP A 484
SER A 652
CYH A 522
LEU A 647
 None
 1.03A 3m0wE-3cf0A:
undetectable
3m0wF-3cf0A:
1.4
3m0wG-3cf0A:
1.6
3m0wH-3cf0A:
undetectable		 3m0wE-3cf0A:
18.03
3m0wF-3cf0A:
18.03
3m0wG-3cf0A:
18.03
3m0wH-3cf0A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 THR A 623
GLY A 621
LEU A 639
ILE A 633
 None
 0.65A 3nbqB-3cf0A:
undetectable		 3nbqB-3cf0A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 8 THR A 623
GLY A 621
LEU A 639
ILE A 633
 None
 0.55A 3nbqC-3cf0A:
undetectable		 3nbqC-3cf0A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		5 / 12 ALA A 622
LEU A 639
ILE A 601
PHE A 563
MET A 608
 None
 1.47A 3qt0A-3cf0A:
undetectable		 3qt0A-3cf0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 586
ARG A 599
TRP A 551
 None
 1.17A 4b7nA-3cf0A:
undetectable		 4b7nA-3cf0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 586
ARG A 599
TRP A 551
 None
 1.20A 4cpzC-3cf0A:
undetectable		 4cpzC-3cf0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 586
ARG A 599
TRP A 551
 None
 1.17A 4cpzE-3cf0A:
undetectable		 4cpzE-3cf0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 586
ARG A 599
TRP A 551
 None
 1.14A 4cpzF-3cf0A:
undetectable		 4cpzF-3cf0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 586
ARG A 599
TRP A 551
 None
 1.08A 4cpzG-3cf0A:
undetectable		 4cpzG-3cf0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 586
ARG A 599
TRP A 551
 None
 1.21A 4cpzH-3cf0A:
undetectable		 4cpzH-3cf0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		3 / 3 ARG A 700
LEU A 697
GLU A 701
 None
 0.62A 4l3gF-3cf0A:
undetectable		 4l3gF-3cf0A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Mus
musculus) 		4 / 6 VAL A 493
LEU A 574
ILE A 542
PHE A 576
 None
 0.68A 5jw1A-3cf0A:
undetectable		 5jw1A-3cf0A:
20.68