SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		5 / 12 GLY B 112
TYR B 188
LEU B  75
LEU B 176
LEU B 141
 None
 1.28A 1fm6D-3cfiB:
undetectable		 1fm6D-3cfiB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		5 / 12 ASN B  86
LEU B 120
VAL B 145
GLU B 175
LEU B 176
 None
 1.23A 2bxfA-3cfiB:
undetectable		 2bxfA-3cfiB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		5 / 12 ASN B  86
LEU B 120
VAL B 145
GLU B 175
LEU B 176
 None
 1.25A 2bxfB-3cfiB:
undetectable		 2bxfB-3cfiB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 4 ILE B  58
GLN B  62
ILE B  89
LEU B 166
 None
 1.34A 3dzyD-3cfiB:
undetectable		 3dzyD-3cfiB:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 7 PHE B  91
LEU B  82
SER B  84
TRP B 125
 None
 0.86A 3hs6B-3cfiB:
undetectable		 3hs6B-3cfiB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 7 PHE B  91
LEU B  82
TRP B 125
VAL B 138
 None
 0.78A 3hs6B-3cfiB:
undetectable		 3hs6B-3cfiB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3cfi NANOBODY NBEPSIJ_11
TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Lama
glama;
Vibrio
vulnificus) 		5 / 12 GLU B 121
PHE C  27
GLY C  26
ASP B  83
ARG C  71
 None
 0.92A 3jzjA-3cfiB:
undetectable		 3jzjA-3cfiB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
NANOBODY NBEPSIJ_11
(Vibrio
vulnificus;
Lama
glama) 		3 / 3 ASP B  83
ARG B 114
ARG C  71
 None
 0.82A 3k37A-3cfiB:
2.0		 3k37A-3cfiB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 7 PHE B  91
ARG B 186
ILE B 184
LEU B 120
 None
 0.92A 3nxuA-3cfiB:
undetectable		 3nxuA-3cfiB:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 3cfi NANOBODY NBEPSIJ_11
(Lama
glama) 		4 / 5 SER C  84
ARG C  86
PRO C  87
VAL C 115
 None
 1.36A 3sufC-3cfiC:
undetectable		 3sufC-3cfiC:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 8 ASN B  98
PRO B  99
PHE B 103
TRP B 124
 None
 1.45A 5amkA-3cfiB:
undetectable		 5amkA-3cfiB:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 8 PHE B  91
ALA B  59
LEU B  74
LEU B  75
 None
 0.94A 5dzkd-3cfiB:
undetectable
5dzkr-3cfiB:
undetectable		 5dzkd-3cfiB:
19.91
5dzkr-3cfiB:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 8 PHE B  91
ALA B  59
LEU B  74
LEU B  75
 None
 0.91A 5dzkF-3cfiB:
undetectable
5dzkT-3cfiB:
undetectable		 5dzkF-3cfiB:
19.91
5dzkT-3cfiB:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
(Vibrio
vulnificus) 		4 / 8 ARG B 151
ASN B 160
PHE B 152
ASP B 154
 None
 1.23A 6auuB-3cfiB:
undetectable		 6auuB-3cfiB:
19.51