SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cfu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3cfu UNCHARACTERIZED
LIPOPROTEIN YJHA
(Bacillus
subtilis) 		4 / 5 SER A 171
VAL A 169
SER A 147
VAL A 145
 None
 1.21A 2j9cA-3cfuA:
undetectable
2j9cB-3cfuA:
undetectable
2j9cC-3cfuA:
undetectable		 2j9cA-3cfuA:
26.04
2j9cB-3cfuA:
26.04
2j9cC-3cfuA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 3cfu UNCHARACTERIZED
LIPOPROTEIN YJHA
(Bacillus
subtilis) 		5 / 12 LEU A 170
VAL A  82
LEU A 209
VAL A 115
ILE A 113
 None
 0.89A 3em6B-3cfuA:
undetectable		 3em6B-3cfuA:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3cfu UNCHARACTERIZED
LIPOPROTEIN YJHA
(Bacillus
subtilis) 		4 / 8 PRO A 144
LEU A 184
VAL A 142
SER A 141
 None
 1.20A 4qknA-3cfuA:
undetectable		 4qknA-3cfuA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3cfu UNCHARACTERIZED
LIPOPROTEIN YJHA
(Bacillus
subtilis) 		5 / 12 GLY A 131
ALA A 191
ASP A 192
GLY A 158
GLY A 157
 None
 0.78A 6dj1A-3cfuA:
undetectable		 6dj1A-3cfuA:
23.81