SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cfy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 LEU A  17
LEU A  14
SER A  11
 None
 0.61A 1tlmA-3cfyA:
undetectable		 1tlmA-3cfyA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 6 ASP A 108
GLU A  25
TYR A  27
LYS A 111
 None
 0.94A 1yc2A-3cfyA:
5.1
1yc2B-3cfyA:
5.0
1yc2E-3cfyA:
4.8		 1yc2A-3cfyA:
20.16
1yc2B-3cfyA:
20.16
1yc2E-3cfyA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 LEU A  56
GLY A  61
ILE A  50
VAL A  77
 None
 0.91A 3wriA-3cfyA:
undetectable		 3wriA-3cfyA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 HIS A 117
ALA A 121
SER A  76
GLU A 124
 None
 0.81A 4hyfA-3cfyA:
undetectable		 4hyfA-3cfyA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 117
ALA A 121
SER A  76
GLU A 124
 None
 0.83A 4hyfB-3cfyA:
undetectable		 4hyfB-3cfyA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 117
ALA A 121
SER A  76
GLU A 124
 None
 0.82A 4hyfC-3cfyA:
undetectable		 4hyfC-3cfyA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 3cfy PUTATIVE LUXO
REPRESSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 GLY A  96
ASP A  66
ILE A  78
PRO A  47
ILE A  68
 None
 1.09A 4njvD-3cfyA:
undetectable		 4njvD-3cfyA:
19.86