SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cg4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H4O_A_BEZA1162_0 (PEROXIREDOXIN 5)	3cg4	RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE) (Methanospirillum hungatei)	5 / 10	PRO A 60 GLY A 61 LEU A 55 THR A 67 GLY A 38	None	1.13A	1h4oA-3cg4A: undetectable 1h4oB-3cg4A: undetectable	1h4oA-3cg4A: 22.78 1h4oB-3cg4A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_B_ECLB600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3cg4	RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE) (Methanospirillum hungatei)	4 / 8	LEU A 85 THR A 86 TYR A 105 ILE A 68	None None GOL A 203 ( 4.9A) None	0.82A	3jusB-3cg4A: undetectable	3jusB-3cg4A: 16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	3cg4	RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE) (Methanospirillum hungatei)	4 / 8	ASP A 13 ASP A 56 ASP A 12 ILE A 106	MG A 201 (-2.9A) MG A 201 (-2.6A) MG A 201 ( 4.2A) None	1.02A	4xjeA-3cg4A: undetectable	4xjeA-3cg4A: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CFS_A_TOYA203_1 (AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN)	3cg4	RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE) (Methanospirillum hungatei)	4 / 8	ASP A 13 ASP A 56 ASP A 12 ILE A 106	MG A 201 (-2.9A) MG A 201 (-2.6A) MG A 201 ( 4.2A) None	1.04A	5cfsA-3cg4A: undetectable	5cfsA-3cg4A: 20.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1H4O_A_BEZA1162_0","PEROXIREDOXIN 5","3cg4","RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE)","Methanospirillum hungatei",5,"PRO A  60;GLY A  61;LEU A  55;THR A  67;GLY A  38","None","1.13A","1h4oA-3cg4A:undetectable;1h4oB-3cg4A:undetectable","1h4oA-3cg4A:22.78;1h4oB-3cg4A:22.78"],["3JUS_B_ECLB600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3cg4","RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE)","Methanospirillum hungatei",4,"LEU A  85;THR A  86;TYR A 105;ILE A  68","None;None;GOL A 203 ( 4.9A);None","0.82A","3jusB-3cg4A:undetectable","3jusB-3cg4A:16.70"],["4XJE_A_TOYA202_1","AADB","3cg4","RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE)","Methanospirillum hungatei",4,"ASP A  13;ASP A  56;ASP A  12;ILE A 106"," MG A 201 (-2.9A); MG A 201 (-2.6A); MG A 201 ( 4.2A);None","1.02A","4xjeA-3cg4A:undetectable","4xjeA-3cg4A:20.94"],["5CFS_A_TOYA203_1","AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN","3cg4","RESPONSE REGULATOR RECEIVER DOMAIN PROTEIN (CHEY-LIKE)","Methanospirillum hungatei",4,"ASP A  13;ASP A  56;ASP A  12;ILE A 106"," MG A 201 (-2.9A); MG A 201 (-2.6A); MG A 201 ( 4.2A);None","1.04A","5cfsA-3cg4A:undetectable","5cfsA-3cg4A:20.94"]]