SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cgl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 5 PRO A 152
LEU A 157
THR A 147
ARG A 221
 None
 0.97A 1i2wA-3cglA:
undetectable		 1i2wA-3cglA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 6 TYR A  91
GLU A 148
ILE A 122
TYR A 120
 None
None
None
CRQ  A  66 ( 4.5A)
 1.09A 1maaB-3cglA:
undetectable
1maaD-3cglA:
undetectable		 1maaB-3cglA:
16.70
1maaD-3cglA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 7 TYR A  91
LEU A 113
TYR A 120
ILE A   8
 None
None
CRQ  A  66 ( 4.5A)
None
 1.16A 1tuvA-3cglA:
undetectable		 1tuvA-3cglA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		3 / 3 LEU A  54
PHE A  27
ARG A  95
 None
None
CRQ  A  66 ( 3.0A)
 0.90A 1xdkB-3cglA:
undetectable		 1xdkB-3cglA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 8 ASN A 109
ILE A 111
PHE A  72
TYR A 120
 CRQ  A  66 ( 4.1A)
None
None
CRQ  A  66 ( 4.5A)
 1.14A 3ccfB-3cglA:
undetectable		 3ccfB-3cglA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 7 THR A  92
GLU A  94
VAL A 180
VAL A 156
 None
 0.56A 3em0B-3cglA:
undetectable		 3em0B-3cglA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 7 GLU A 148
HIS A 194
VAL A  73
ALA A 218
 None
 1.05A 3kp6B-3cglA:
undetectable		 3kp6B-3cglA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		5 / 10 PHE A  22
PHE A  27
PHE A 124
THR A 140
PHE A 129
 None
 1.34A 3t3qA-3cglA:
undetectable		 3t3qA-3cglA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		3 / 3 LYS A 199
VAL A 201
HIS A 215
 None
 0.47A 3tj7A-3cglA:
undetectable		 3tj7A-3cglA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		5 / 12 PHE A  56
ASN A 205
LEU A  46
VAL A  48
ILE A  29
 None
 0.68A 4k39A-3cglA:
undetectable		 4k39A-3cglA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		3 / 3 PRO A 191
MET A 190
TYR A  82
 None
 0.78A 4qa0B-3cglA:
undetectable		 4qa0B-3cglA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		3 / 3 PRO A 191
MET A 190
TYR A  82
 None
 0.80A 4qa0A-3cglA:
undetectable		 4qa0A-3cglA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		3 / 3 PRO A 191
MET A 190
TYR A  82
 None
 0.85A 4qa2B-3cglA:
undetectable		 4qa2B-3cglA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 5 LEU A 150
TYR A 151
LEU A 157
TYR A 181
 None
 1.40A 5ki6A-3cglA:
undetectable		 5ki6A-3cglA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483
(Discosoma
striata) 		4 / 8 VAL A  44
LEU A  46
ILE A 122
ASN A 109
 CRQ  A  66 ( 4.3A)
None
None
CRQ  A  66 ( 4.1A)
 0.82A 5nujA-3cglA:
undetectable		 5nujA-3cglA:
13.88