SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ch2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		4 / 4 SER X 816
ILE X 814
VAL X 764
THR X 607
 None
 1.13A 1u70A-3ch2X:
undetectable		 1u70A-3ch2X:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		3 / 3 ILE X 598
ILE X 648
LEU X 585
 None
 0.54A 2prgA-3ch2X:
undetectable		 2prgA-3ch2X:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GF2_A_SALA147_1
(146AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		4 / 4 TYR X 798
LEU X 575
ARG X 574
TYR X 603
 None
 1.48A 3gf2A-3ch2X:
0.0		 3gf2A-3ch2X:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		5 / 10 TYR X 663
LEU X 622
THR X 595
ILE X 648
ILE X 598
 None
 1.42A 3kcxA-3ch2X:
undetectable		 3kcxA-3ch2X:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		4 / 7 ASN X 626
GLN X 590
PRO X 673
TYR X 661
 None
 1.19A 3ugrA-3ch2X:
undetectable		 3ugrA-3ch2X:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		5 / 11 ILE X 733
ALA X 600
GLU X 606
GLY X 797
ASN X 765
 None
 1.26A 4e47B-3ch2X:
undetectable		 4e47B-3ch2X:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		4 / 4 ALA X 600
VAL X 732
GLY X 730
THR X 607
 None
 0.92A 4ubeA-3ch2X:
undetectable		 4ubeA-3ch2X:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		4 / 8 PHE X 811
SER X 708
ALA X 760
GLY X 756
 None
 0.97A 4xk8a-3ch2X:
undetectable		 4xk8a-3ch2X:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 3ch2 SERINE-REPEAT
ANTIGEN PROTEIN
(Plasmodium
falciparum) 		4 / 5 LYS X 780
GLU X 778
GLY X 777
SER X 775
 None
 1.40A 5jhdJ-3ch2X:
undetectable		 5jhdJ-3ch2X:
18.98