SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ch7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		4 / 8 GLU A  76
LEU A 137
ALA A  42
VAL A 156
 None
 0.66A 1a29A-3ch7A:
undetectable		 1a29A-3ch7A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 THR A 169
PHE A   4
LEU A 232
VAL A 265
ALA A 261
 None
 1.49A 1q23D-3ch7A:
undetectable
1q23E-3ch7A:
undetectable		 1q23D-3ch7A:
22.22
1q23E-3ch7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		4 / 8 GLY A 125
GLY A 122
GLY A 121
LEU A 123
 None
 0.66A 1qzzA-3ch7A:
undetectable		 1qzzA-3ch7A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 9 TYR A  53
LEU A 218
VAL A 216
ILE A  25
VAL A  24
 None
 1.46A 2l8mA-3ch7A:
undetectable		 2l8mA-3ch7A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		4 / 7 GLY A 122
GLY A 121
SER A 116
LEU A  78
 None
 0.75A 2oa1B-3ch7A:
undetectable		 2oa1B-3ch7A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 9 LEU A  52
LEU A  43
ALA A  94
LEU A  96
PHE A  71
 None
 1.23A 2vcvI-3ch7A:
undetectable		 2vcvI-3ch7A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 GLY A  46
VAL A 228
GLY A 164
ALA A 220
ALA A 261
 None
 1.12A 3keeB-3ch7A:
undetectable		 3keeB-3ch7A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 VAL A 265
LEU A 232
GLY A 260
ALA A 261
LEU A 257
 None
 1.17A 3pghA-3ch7A:
undetectable		 3pghA-3ch7A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 ILE A  25
VAL A  69
ALA A 212
LEU A 204
VAL A 208
 None
 1.15A 3w67C-3ch7A:
undetectable		 3w67C-3ch7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 GLY A 162
HIS A 168
ASP A 166
MET A 195
GLY A 167
 None
 1.15A 4qa2B-3ch7A:
2.7		 4qa2B-3ch7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 7 GLY A 251
VAL A 156
ASP A 157
ILE A 158
VAL A 159
 None
 1.34A 5ik1A-3ch7A:
undetectable		 5ik1A-3ch7A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 GLY A 162
SER A  44
VAL A 231
VAL A 216
LEU A 255
 None
 1.00A 5kocA-3ch7A:
undetectable		 5kocA-3ch7A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		5 / 12 GLY A 162
SER A  44
VAL A 231
VAL A 216
LEU A 255
 None
 1.03A 5kocB-3ch7A:
undetectable		 5kocB-3ch7A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		3 / 3 VAL A 202
VAL A 188
GLN A 131
 None
 0.72A 5qgwA-3ch7A:
undetectable		 5qgwA-3ch7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		3 / 3 VAL A 202
VAL A 188
GLN A 131
 None
 0.71A 5qh9A-3ch7A:
undetectable		 5qh9A-3ch7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		3 / 3 VAL A 202
VAL A 188
GLN A 131
 None
 0.71A 5qhfA-3ch7A:
undetectable		 5qhfA-3ch7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		4 / 8 LEU A 161
LEU A 218
ALA A 219
LEU A 257
 None
 0.70A 5y7pE-3ch7A:
undetectable		 5y7pE-3ch7A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3ch7 6-PHOSPHOGLUCONOLACT
ONASE
(Leishmania
braziliensis) 		3 / 3 TYR A  53
ALA A  21
LEU A 160
 None
 0.69A 6d9kF-3ch7A:
undetectable		 6d9kF-3ch7A:
15.98