SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3chi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		3 / 3 TRP A 191
ALA A 105
VAL A 194
 None
 0.90A 1bdwA-3chiA:
undetectable
1bdwB-3chiA:
undetectable		 1bdwA-3chiA:
3.82
1bdwB-3chiA:
3.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 8 ARG A 244
VAL A 116
GLY A 115
MET A 113
 None
 0.99A 1hrkA-3chiA:
undetectable		 1hrkA-3chiA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 8 ARG A 244
VAL A 116
GLY A 115
MET A 113
 None
 0.99A 1hrkB-3chiA:
undetectable		 1hrkB-3chiA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifA-3chiA:
undetectable		 1kifA-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifB-3chiA:
undetectable		 1kifB-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifC-3chiA:
undetectable		 1kifC-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifD-3chiA:
undetectable		 1kifD-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifE-3chiA:
undetectable		 1kifE-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifF-3chiA:
undetectable		 1kifF-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifG-3chiA:
undetectable		 1kifG-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 1kifH-3chiA:
undetectable		 1kifH-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 ASP A 185
LEU A 171
ALA A 108
LEU A 111
 None
 1.08A 1nh8A-3chiA:
undetectable		 1nh8A-3chiA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.13A 1ve9A-3chiA:
undetectable		 1ve9A-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_B_BEZB1352_0
(D-AMINO ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 4 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.16A 1ve9B-3chiA:
0.0		 1ve9B-3chiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		5 / 6 LEU A 206
TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.30A 2du8A-3chiA:
undetectable		 2du8A-3chiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		5 / 6 LEU A 206
TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.29A 2du8B-3chiA:
undetectable		 2du8B-3chiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 TYR A  93
TYR A  61
ILE A  65
ARG A  96
 None
 1.08A 2du8G-3chiA:
undetectable		 2du8G-3chiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 5 LEU A 206
ALA A 204
LEU A 224
MET A 142
 None
 1.21A 2oaxA-3chiA:
2.2		 2oaxA-3chiA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		3 / 3 GLU A 101
HIS A 230
GLU A 196
 FEO  A 501 (-2.1A)
FEO  A 501 (-3.2A)
FEO  A 501 (-2.1A)
 0.70A 2x45B-3chiA:
undetectable		 2x45B-3chiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		3 / 3 GLU A 196
HIS A 139
GLU A 101
 FEO  A 501 (-2.1A)
FEO  A 501 (-3.3A)
FEO  A 501 (-2.1A)
 0.64A 2x45B-3chiA:
undetectable		 2x45B-3chiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		3 / 3 GLU A 101
HIS A 230
GLU A 196
 FEO  A 501 (-2.1A)
FEO  A 501 (-3.2A)
FEO  A 501 (-2.1A)
 0.70A 2x45C-3chiA:
undetectable		 2x45C-3chiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		3 / 3 GLU A 196
HIS A 139
GLU A 101
 FEO  A 501 (-2.1A)
FEO  A 501 (-3.3A)
FEO  A 501 (-2.1A)
 0.64A 2x45C-3chiA:
undetectable		 2x45C-3chiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 6 LEU A 257
VAL A 320
PHE A 324
VAL A 194
 None
 1.10A 3soaA-3chiA:
undetectable		 3soaA-3chiA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 7 GLY A 192
ALA A 193
GLU A 196
THR A 197
 None
None
FEO  A 501 (-2.1A)
None
 0.65A 4r1zB-3chiA:
2.0		 4r1zB-3chiA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		5 / 12 VAL A  32
LEU A 189
ARG A 239
THR A 197
GLY A 231
 None
 1.24A 6brdA-3chiA:
undetectable		 6brdA-3chiA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3chi P-AMINOBENZOATE
N-OXYGENASE
(Streptomyces
thioluteus) 		4 / 8 ASP A 148
ARG A 151
GLU A  95
GLU A 158
 None
 1.29A 6mn4C-3chiA:
undetectable		 6mn4C-3chiA:
23.73