SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ci0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3ci0 PSEUDOPILIN GSPI
(Escherichia
coli) 		4 / 7 LEU I  51
TYR I  52
THR I  83
TRP I 111
 None
 1.11A 1afsA-3ci0I:
undetectable		 1afsA-3ci0I:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3ci0 PSEUDOPILIN GSPI
(Escherichia
coli) 		4 / 7 LEU I  51
TYR I  52
THR I  83
TRP I 111
 None
 1.11A 1afsB-3ci0I:
undetectable		 1afsB-3ci0I:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		3 / 3 ARG K  30
SER K  44
TYR K  43
 None
 0.74A 1x70A-3ci0K:
4.0		 1x70A-3ci0K:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 218
ALA K 221
LEU K 119
ALA K 118
LEU K 271
 None
 0.99A 1xdkA-3ci0K:
undetectable		 1xdkA-3ci0K:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 218
ALA K 221
LEU K 119
ALA K 118
LEU K 271
 None
 0.98A 1xdkE-3ci0K:
undetectable		 1xdkE-3ci0K:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 218
ALA K 221
LEU K 119
ALA K 118
LEU K 271
 None
 1.02A 1xiuA-3ci0K:
undetectable		 1xiuA-3ci0K:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3ci0 PSEUDOPILIN GSPI
PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 8 SER K  49
PHE I 112
TYR I  52
LEU I  81
 None
 0.76A 2bfpC-3ci0K:
undetectable		 2bfpC-3ci0K:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 5 LEU K  55
ILE K 297
LEU K 296
SER K 295
 None
 0.82A 2byoA-3ci0K:
2.6		 2byoA-3ci0K:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3ci0 PSEUDOPILIN GSPI
PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 8 SER K  49
VAL K  87
TYR I  52
ASN I  85
 None
 1.12A 2wekA-3ci0K:
undetectable		 2wekA-3ci0K:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3ci0 PSEUDOPILIN GSPJ
(Escherichia
coli) 		4 / 5 ARG J  92
MET J  58
THR J  56
LEU J 188
 None
 1.40A 3ag2J-3ci0J:
undetectable		 3ag2J-3ci0J:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		3 / 3 LEU K 211
VAL K  65
ARG K 239
 None
 0.67A 3b0wB-3ci0K:
undetectable		 3b0wB-3ci0K:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ALA K  94
LEU K  67
LEU K  59
ARG K 299
PHE K 278
 None
 1.11A 3datA-3ci0K:
undetectable		 3datA-3ci0K:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 8 LYS K 193
ARG K 129
MET K 178
GLU K 314
 None
 1.17A 3dh0A-3ci0K:
undetectable		 3dh0A-3ci0K:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 218
ALA K 221
LEU K 119
ALA K 118
LEU K 271
 None
 1.12A 3dzyA-3ci0K:
undetectable		 3dzyA-3ci0K:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3ci0 PSEUDOPILIN GSPI
PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 8 SER K  49
PHE I 112
TYR I  52
LEU I  81
 None
 0.64A 3jq7B-3ci0K:
undetectable		 3jq7B-3ci0K:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 3ci0 PSEUDOPILIN GSPI
PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 8 SER K  49
PHE I 112
TYR I  52
LEU I  81
 None
 0.65A 3jq7C-3ci0K:
undetectable		 3jq7C-3ci0K:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 6 LEU K 291
SER K  44
TYR K  43
ALA K  45
 None
 1.04A 3ravA-3ci0K:
undetectable		 3ravA-3ci0K:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 TRP K 279
LEU K 199
LEU K 172
ILE K 175
PHE K 140
 None
 1.38A 4a79A-3ci0K:
undetectable		 4a79A-3ci0K:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 TRP K 279
LEU K 199
LEU K 172
ILE K 175
PHE K 140
 None
 1.40A 4a79B-3ci0K:
undetectable		 4a79B-3ci0K:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 6 ALA K 100
ASN K  99
LEU K 101
GLU K 177
 None
 1.04A 4g24A-3ci0K:
undetectable		 4g24A-3ci0K:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 7 ILE K 206
LEU K 267
ALA K 221
ILE K 218
 None
 0.84A 4y03A-3ci0K:
undetectable		 4y03A-3ci0K:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 5 VAL K 113
TYR K 277
ILE K 297
THR K 210
 None
 1.25A 4ze1A-3ci0K:
undetectable		 4ze1A-3ci0K:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3ci0 PSEUDOPILIN GSPJ
PSEUDOPILIN GSPK
(Escherichia
coli;
Escherichia
coli) 		5 / 12 GLY J  93
GLN J 138
TYR J 112
THR K 312
GLN K 311
 None
 1.26A 5hg0A-3ci0J:
undetectable		 5hg0A-3ci0J:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 218
ALA K 221
LEU K 119
ALA K 118
LEU K 271
 None
 0.95A 5uanA-3ci0K:
undetectable		 5uanA-3ci0K:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ci0 PSEUDOPILIN GSPJ
(Escherichia
coli) 		4 / 5 ARG J  92
MET J  58
THR J  56
LEU J 188
 None
 1.45A 5x1bW-3ci0J:
undetectable		 5x1bW-3ci0J:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 218
ALA K 221
LEU K 119
ALA K 118
LEU K 271
 None
 1.12A 6a5zD-3ci0K:
undetectable		 6a5zD-3ci0K:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		5 / 12 ILE K 208
VAL K 270
LEU K 267
LEU K 219
LEU K 222
 None
 1.11A 6ajiA-3ci0K:
undetectable		 6ajiA-3ci0K:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3ci0 PSEUDOPILIN GSPI
PSEUDOPILIN GSPJ
PSEUDOPILIN GSPK
(Escherichia
coli;
Escherichia
coli;
Escherichia
coli) 		4 / 5 GLU I  45
LEU K  41
HIS K 310
THR J  52
 None
 1.30A 6dyoA-3ci0I:
undetectable		 6dyoA-3ci0I:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3ci0 PSEUDOPILIN GSPK
(Escherichia
coli) 		4 / 7 ASP K 142
ASP K 144
GLN K 148
TYR K 158
 CA  K 401 ( 2.1A)
CA  K 401 ( 2.4A)
CA  K 401 (-2.8A)
None
 1.10A 6g31G-3ci0K:
undetectable		 6g31G-3ci0K:
14.43